Abstract: Disclosed embodiments relate to a wound dressing which can contain and release oxygen. The wound dressing may include one or more perfluorocarbon layers, a membrane electrolytic assembly, one or more dressing layers, and a durable binding layer. The one or more perfluorocarbon layers may contain nonafluorohexyltriethoxysilane, 1H, 1H, 2H, 2H-perfluorodecyltriethoxysilane, 1H, 1H, 2H, 2H-perfluorooctyltriethoxysilane, or pentafluorophenyltriethoxysilane. The wound dressing may also include other layers.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, an activator layer such as an acid providing layer and nitric oxide source layer, such as a nitrite providing layer. The activator layer may include acidic groups and may be hydrogel, xerogel, or other suitable material. The nitric oxide source layer may include a nitrite salt. Nitrite ions of the nitric oxide source layer may react with the acidic groups of the activating layer to generate nitric oxide. The wound dressing may further include a composite layer, such as a layer with an acquisition distribution layer embedded within an activator gel layer. Additional composite layers may include various absorbent materials embedded within an activator gel layer.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, a nitric oxide source layer, such as a nitrite providing layer, an absorbent layer such as a foam, and a gel material adhered to the absorbent layer. The gel material may include perforations in a cured pattern structure. The perforations may define a plurality of fluid channels extending through the gel material. The gel material may form an active wound contact layer for use in generating nitric oxide.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, an activator layer such as an acid providing layer and nitric oxide source layer, such as a nitrite providing layer. The activator layer may include acidic groups and may be hydrogel, xerogel, or other suitable material. The activator layer may include a copolymer of monomers with one or more covalently linked multifunctional groups.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, an activator layer such as an acid providing layer and nitric oxide source layer, such as a nitrite providing layer. The activator layer may include acidic groups and may be hydrogel, xerogel, or other suitable material. The nitric oxide source layer may include a nitrite salt. Nitrite ions of the nitric oxide source layer may react with the acidic groups of the activating layer to generate nitric oxide. The activating layer may include a window at the center, and a central absorbent material may be positioned at the window. Various separating layers may also be incorporated into the dressing to control the interaction between activating layer and nitric oxide source layer.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing comprises a cover layer, an acid providing layer and a nitrite providing layer. The acid providing layer comprises acidic groups and may be hydrogel or Xerogel. The nitrite providing layer comprises a nitrite salt. The wound dressing may also include other layers, one or more acquisition distribution layers or masking layers. The masking layers can at least partially prevent visualization of the layer below the masking layer. Nitrite ions of the nitrite providing layer may react with the acidic groups of the acid providing layer to generate nitric oxide. The acid providing layer further includes one or more material layers to reduce the adhesiveness of the acid providing layer. The acid providing layer can also include perforations.

Abstract: Disclosed embodiments relate to wound care materials and methods that comprise a self-gelling composition, configured to form a gel upon contacting fluid. The self-gelling composition is a substantially homogeneous mixture, and comprises fluid-absorbent particles loaded with iodine-based antimicrobial agent, a dehydrated hydrogel powder, and a polymer base, configured to allow dispensing the self-gelling composition from a syringe or tube and to prevent the self-gelling composition from gelling prior to contacting fluid. The gel performs one or more of the following tasks during a wear time, when applied at the wound: absorbing fluid or exudate, releasing iodine-based antimicrobial agent, achieving antimicrobial activities at the wound, remaining structurally integral and cohesive, protecting the wound from exposure to microorganisms, and facilitating healing. After a wear time of at least three days, the gel can be removed in two pieces or less and leave less than 5% residue by weight.