Abstract: A medical device that includes an outer body configured to visually mark a target tissue such that the target tissue is detectable by an imaging system. The medical device includes a sensor disposed within the outer body, wherein the sensor is configured to detect radiation at the target site.

Abstract: The present invention relates to an improved online auction reservation system and method which allows a user to bid for, obtain and reserve a booth/table/location at a selected venue in that network. A computing device associated with the network interconnects a plurality of venues through the network, allowing user to attempt to obtain reservations on selected date at a selected venue within the network. The users can then select a specified reservation location within that selected venue, and an on-line auction process ensues from different users within the network to secure a specified reservation location and time within the selected venue. The auction bids are assessed from amongst the bidders to establish a highest bid for that reservation within the selected venue, and the reservation is ultimately awarded to the highest bidder.

Abstract: The present invention concerns methods and compositions for prophylactic or therapeutic treatment of skin disorders by administering therapeutically or prophylactically effective amounts of a probiotic. The present invention is also concerned with the treatment of symptoms of skin disorders.

Abstract: A method of treating an inflammatory condition involving TNF-? in a mammal by administering to a patient a composition with an effective amount of an isolated alkaline protease in an amount effective to inactive TNF-?. The invention also involves compositions, including pharmaceutical compositions containing an isolated alkaline protease in an amount effective to inactive TNF-? especially those from Aspergillus oryzae and/or serve as a transepithial carrier.

Abstract: Compositions that may be usefully employed to alleviate symptoms resulting from deficiencies in carbohydrate enzymes, together with methods for the treatment of disorders that are characterized by such deficiencies, such as autism, are provided. The compositions preferably comprise transglucosidase isolated from A. niger.

Abstract: A method of treating an inflammatory condition involving TNF-? in a mammal by administering to a patient a composition with an effective amount of an isolated alkaline protease in an amount effective to inactive TNF-?. The invention also involves compositions, including pharmaceutical compositions containing an isolated alkaline protease in an amount effective to inactive TNF-? especially those from Aspergillus oryzae.

Abstract: Compositions that may be usefully employed to alleviate symptoms resulting from deficiencies in carbohydrate enzymes, together with methods for the treatment of disorders that are characterized by such deficiencies, such as autism, are provided. The compositions preferably comprise transglucosidase isolated from A. niger.