Patents by Inventor Anthony Daniyan

Anthony Daniyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-36 SECRETING IMMUNORESPONSIVE CELLS AND USES THEREOF
    Publication number: 20240108705
    Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing increased level of IL-36. In certain embodiments, the engineered immunoresponsive cells are antigen-directed and have enhanced immune-activating properties.
    Type: Application
    Filed: August 10, 2023
    Publication date: April 4, 2024
    Applicant: Memorial Sloan-Kettering Cancer Center
    Inventors: Anthony Daniyan, Renier J. Brentjens
  • IL-36 secreting immunoresponsive cells and uses thereof
    Patent number: 11766474
    Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing increased level of IL-36. In certain embodiments, the engineered immunoresponsive cells are antigen-directed and have enhanced immune-activating properties.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: September 26, 2023
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Anthony Daniyan, Renier J. Brentjens
  • IL-33 SECRETING IMMUNORESPONSIVE CELLS AND USES THEREOF
    Publication number: 20230242879
    Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing increased level of IL-33. In certain embodiments, the engineered immunoresponsive cells are antigen-directed and have enhanced immune-activating properties.
    Type: Application
    Filed: March 23, 2023
    Publication date: August 3, 2023
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Anthony Daniyan, Renier J. Brentjens
  • CHIMERIC ANTIGEN RECEPTORS WITH CD28 MUTATIONS AND USE THEREOF
    Publication number: 20230051064
    Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) comprising a mutated CD28 intracellular motif, and cells comprising such CARs. The presently disclosed subject matter further relates to the use of said cells for treating diseases, e.g., for treating cancers.
    Type: Application
    Filed: August 5, 2022
    Publication date: February 16, 2023
    Applicant: Memorial Sloan-Kettering Cancer Center
    Inventors: Anthony Daniyan, Renier J. Brentjens
  • ANTIGEN RECOGNIZING RECEPTORS TARGETING CD371 AND USES THEREOF
    Publication number: 20220213211
    Abstract: The presently disclosed subject matter provides for antigen-recognizing receptors that specifically target CD371 and cells comprising such CD371-targeted antigen-recognizing receptors. The presently disclosed subject matter further provides uses of the CD371-targeted antigen-recognizing receptors for treatment.
    Type: Application
    Filed: March 11, 2022
    Publication date: July 7, 2022
    Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER, TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, INC., SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH, MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES
    Inventors: Anthony Daniyan, Renier J. Brentjens, Ivo C. Lorenz, Mary Ann Pohl
  • ANTI-CD371 ANTIBODIES AND USES THEREOF
    Publication number: 20220195064
    Abstract: The presently disclosed subject matter provides antibodies or antigen-binding fragments thereof that bind to CD371 and methods of using such antibodies or antigen-binding fragments thereof same.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 23, 2022
    Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER, TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, INC., SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH, MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES
    Inventors: Anthony Daniyan, Renier J. Brentjens, Ivo C. Lorenz, Mary Ann Pohl
  • IL-33 SECRETING IMMUNORESPONSIVE CELLS AND USES THEREOF
    Publication number: 20200399598
    Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing increased level of IL-33. In certain embodiments, the engineered immunoresponsive cells are antigen-directed and have enhanced immune-activating properties.
    Type: Application
    Filed: May 13, 2020
    Publication date: December 24, 2020
    Applicant: Memorial Sloan-Kettering Cancer Center
    Inventors: Anthony Daniyan, Renier J. Brentjens
  • IL-36 SECRETING IMMUNORESPONSIVE CELLS AND USES THEREOF
    Publication number: 20200330574
    Abstract: The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing increased level of IL-36. In certain embodiments, the engineered immunoresponsive cells are antigen-directed and have enhanced immune-activating properties.
    Type: Application
    Filed: May 13, 2020
    Publication date: October 22, 2020
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Anthony Daniyan, Renier J. Brentjens