Patents by Inventor Anthony DORE

Anthony DORE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VEGF-Aassay
    Patent number: 9459263
    Abstract: The invention provides a method for enriching the level of VEGF-A121 isoform in a sample by selectively removing the VEGF-A165 isoform from the sample using a neuropilin-1 pull-down procedure, then determining the total amount of VEGF-A remaining afterward. The invention provides methods of treating a patient suffering from a disease which may benefit from the administration of a VEGF antagonist by determining the level or ratio of VEGF-A121 in the patient's circulation. Methods of diagnosis, prognosis, monitoring, and patient stratification are also provided.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: October 4, 2016
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Nicholas Papadopoulos, Anthony Dore, Douglas MacDonald
  • VEGF-A121 ASSAY
    Publication number: 20150330999
    Abstract: The invention provides a method for enriching the level of VEGF-A121 isoform in a sample by selectively removing the VEGF-A165 isoform from the sample using a neuropilin-1 pull-down procedure, then determining the total amount of VEGF-A remaining afterward. The invention provides methods of treating a patient suffering from a disease which may benefit from the administration of a VEGF antagonist by determining the level or ratio of VEGF-A121 in the patient's circulation. Methods of diagnosis, prognosis, monitoring, and patient stratification are also provided.
    Type: Application
    Filed: July 28, 2015
    Publication date: November 19, 2015
    Inventors: Nicholas PAPADOPOULOS, Anthony DORE, Douglas MACDONALD
  • VEGF-A121 ASSAY
    Publication number: 20150330998
    Abstract: The invention provides a method for enriching the level of VEGF-A121 isoform in a sample by selectively removing the VEGF-A165 isoform from the sample using a neuropilin-1 pull-down procedure, then determining the total amount of VEGF-A remaining afterward. The invention provides methods of treating a patient suffering from a disease which may benefit from the administration of a VEGF antagonist by determining the level or ratio of VEGF-A121 in the patient's circulation. Methods of diagnosis, prognosis, monitoring, and patient stratification are also provided.
    Type: Application
    Filed: July 28, 2015
    Publication date: November 19, 2015
    Inventors: Nicholas PAPADOPOULOS, Anthony DORE, Douglas MACDONALD
  • VEGF-Aassay
    Patent number: 9116159
    Abstract: The invention provides a method for determining the level of VEGF-A121 isoform in a sample by selectively removing the VEGF-A165 isoform from the sample using a neuropilin-1 pull-down procedure, then determining the total amount of VEGF-A remaining afterward. The invention provides methods of treating a patient suffering from a disease which may benefit from the administration of a VEGF antagonist by determining the level of VEGF-A121 in the patient's circulation. Methods of diagnosis, prognosis, monitoring, and patient stratification are also provided.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: August 25, 2015
    Assignee: REGENERON PHARMACEUTICALS, INC.
    Inventors: Nicholas Papadopoulos, Anthony Dore, Douglas MacDonald
  • VEGF-A121 ASSAY
    Publication number: 20130315907
    Abstract: The invention provides a method for determining the level of VEGF-A121 isoform in a sample by selectively removing the VEGF-A165 isoform from the sample using a neuropilin-1 pull-down procedure, then determining the total amount of VEGF-A remaining afterward. The invention provides methods of treating a patient suffering from a disease which may benefit from the administration of a VEGF antagonist by determining the level of VEGF-A121 in the patient's circulation. Methods of diagnosis, prognosis, monitoring, and patient stratification are also provided.
    Type: Application
    Filed: May 22, 2013
    Publication date: November 28, 2013
    Inventors: Nicholas PAPADOPOULOS, Anthony DORE, Douglas MACDONALD