Abstract: A computing device includes an appliance status table to store at least one of reliability and performance data for one or more network functions virtualization (NFV) appliances and one or more legacy network appliances. The computing device includes a load controller to configure an Internet Protocol (IP) filter rule to select a packet for which processing of the packet is to be migrated from a selected one of the one or more legacy network appliances to a selected one of the one or more NFV appliances, and to update the appliance status table with received at least one of reliability and performance data for the one or more legacy network appliances and the one or more NFV appliances. The computing device includes a packet distributor to receive the packet, to select one of the one or more NFV appliances based at least in part on the appliance status table, and to send the packet to the selected NFV appliance. Other embodiments are described herein.

Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example. build muscle strength and/or reduce muscle tremors.

Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.

Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.

Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.

Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.

Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example. build muscle strength and/or reduce muscle tremors.

Abstract: Disclosed herein are fully human antibody molecules that immunospecifically bind to human IL-5. The antibody molecules can bind to human IL-5 with an equilibrium affinity constant (KD) of at least about 40 pM as determined by surface plasmon resonance.

Abstract: Disclosed herein are fully human antibody molecules that immunospecifically bind to human IL-5. The antibody molecules can bind to human IL-5 with an equilibrium affinity constant (KD) of at least about 40 pM as determined by surface plasmon resonance.

Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example, build muscle strength and/or reduce muscle tremors.

Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.

Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.

Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.

Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example, build muscle strength and/or reduce muscle tremors.

Abstract: This invention relates generally to a muscle activating and exercising device and a method of activating and exercising muscles of the human body. More particularly, it relates to an elongated device that is pliable enough to be wrapped around an object. Such device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis rack). The present invention also relates to a method of activating muscles using a pliable device. Through such a method, a user can, for example. build muscle strength and/or reduce muscle tremors.

Abstract: Disclosed herein are fully human antibody molecules that immunospecifically bind to human IL-5. The antibody molecules can bind to human IL-5 with an equilibrium affinity constant (KD) of at least about 40 pM as determined by surface plasmon resonance.

Abstract: A dimmer switch for an LED light source utilizes a thyristor-type device (“TTD”) having a first terminal, a second terminal, and a gate terminal. A low-voltage power supply converts alternating voltage into a direct voltage and is connected in parallel with the TTD. Gate current supplying circuitry is provided to supply current to the gate of the TTD, the gate current supplying circuitry powered by the low-voltage power supply and including a variable input device operable to vary a voltage waveform at the gate of the TTD in order to vary a voltage waveform provided at the second terminal.

Abstract: This invention relates to an insulated article. The insulated articles comprise either a twin walled construction and/or a protective pouch of packaging material encompassing a layer of insulating material. The insulating material comprises an aerogel material such as silica aerogel material and the function of the insulation is to minimize energy usage in the articles. One particularly preferred article is an oven constructed with an inner and an outer wall and a layer of aerogel insulation encapsulated in a packaging material therebetween. A transparent insulation may be used for the front door of the oven or alternatively a camera capturing images inside the oven may be provided in conjunction with a visual display for displaying the images captured by the camera. The energy consumption of the oven is reduced significantly. Similar techniques can also be applied to other articles of manufacture including hot water cylinders, beverage and food containers, radiators and fireplace surrounds to name a few.

Abstract: A control circuit for controlling current through a load comprises a first terminal for connection to an alternating voltage source, a second terminal for connection to the load and a thyristor-type device having a gate terminal, connected between the first and second terminals. Voltage regulation means is provided for converting alternating voltage into a direct voltage and is connected between the first and second terminals in parallel with the thyristor-type device. Gate current supplying means is provided to supply current to the gate of the thyristor-type device, the gate current supplying means being powered by the voltage regulation means and including a variable input device operable to vary a voltage waveform at the gate of the thyristor-type device in order to vary the voltage waveform provided at the second terminal.

Abstract: This invention relates to an energy saving electric kettle. The energy saving electric kettle comprises a liquid container having a charging inlet, a discharge outlet and a heating element for heating the contents of the container. The container comprises an inner wall, an outer wall and an insulation layer therebetween. The insulation layer comprises an aerogel material. Preferably, the aerogel material is a glass fibre continuous filament silica aerogel which is particularly suitable for this purpose and is efficient in operation. After boiling, the kettle maintains the water at a higher temperature for longer and furthermore will significantly reduce the energy requirement on re-boiling of the kettle.