Patents by Inventor ANTHONY DOYLE
ANTHONY DOYLE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250033950Abstract: A portable fuel metering system (PMU) is described. The PMU has one or more flow meters capable of metering the flow of fluids, such as fuel, as the fluid is transferred from a source to a receiver. The PMU may include a telemetry unit configured to transmit parameters related to the fuel transfer to remote location. The PMU may be configured in a light, portable package that may be carried by one or two people. The PMU may include a power generator that is configured to use the flow of fluid to the PMU to generate power for the PMU's operation.Type: ApplicationFiled: October 10, 2024Publication date: January 30, 2025Inventors: Thomas Smith, John Donovan, Emerson Ornstein, Brian Doyle, Anthony George
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Publication number: 20240301076Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.Type: ApplicationFiled: May 16, 2024Publication date: September 12, 2024Inventors: Doris Shim Siew Chen, Lynn Dorothy Poulton, Adam Clarke, David Jose Simon Laine, Matthew Pollard, Bridget Ann Cooksey, Anthony Doyle, Jason William Gill
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Patent number: 12018084Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.Type: GrantFiled: April 12, 2022Date of Patent: June 25, 2024Assignee: Cephalon LLCInventors: Doris Shim Siew Chen, Lynn Dorothy Poulton, Adam Clarke, David Jose Simon Laine, Matthew Pollard, Bridget Ann Cooksey, Anthony Doyle, Jason William Gill
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Patent number: 11673016Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example. build muscle strength and/or reduce muscle tremors.Type: GrantFiled: August 6, 2021Date of Patent: June 13, 2023Assignee: LACEUP ATHLETICS LLCInventors: Jay Ciccarone, Anthony Doyle, Jr.
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Publication number: 20220348671Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.Type: ApplicationFiled: April 12, 2022Publication date: November 3, 2022Inventors: Doris Shim Siew Chen, Lynn Dorothy Poulton, Adam Clarke, David Jose Simon Laine, Matthew Pollard, Bridget Ann Cooksey, Anthony Doyle, Jason William Gill
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Publication number: 20220220184Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.Type: ApplicationFiled: March 31, 2022Publication date: July 14, 2022Inventors: Collette Behrens, Anthony Doyle, Adam Clarke, Matthew Pollard, Teresa Domagala
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Patent number: 11332534Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.Type: GrantFiled: July 31, 2019Date of Patent: May 17, 2022Assignee: Cephalon, Inc.Inventors: Doris Shim Siew Chen, Lynn Dorothy Poulton, Adam Clarke, David Jose Simon Laine, Matthew Pollard, Bridget Ann Cooksey, Anthony Doyle, Jason William Gill
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Patent number: 11319356Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.Type: GrantFiled: December 11, 2019Date of Patent: May 3, 2022Assignee: Teva Pharmaceuticals Australia Pty LtdInventors: Collette Behrens, Anthony Doyle, Adam Clarke, Matthew Pollard, Teresa Domagala
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Publication number: 20210361995Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example. build muscle strength and/or reduce muscle tremors.Type: ApplicationFiled: August 6, 2021Publication date: November 25, 2021Inventors: Jay Ciccarone, Anthony Doyle, JR.
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Publication number: 20210355205Abstract: Disclosed herein are fully human antibody molecules that immunospecifically bind to human IL-5. The antibody molecules can bind to human IL-5 with an equilibrium affinity constant (KD) of at least about 40 pM as determined by surface plasmon resonance.Type: ApplicationFiled: July 26, 2021Publication date: November 18, 2021Inventors: Mark Terence Liddament, Anthony Doyle, Adam Clarke, David Jose Simon Laine, Bridget Ann Cooksey
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Patent number: 11111292Abstract: Disclosed herein are fully human antibody molecules that immunospecifically bind to human IL-5. The antibody molecules can bind to human IL-5 with an equilibrium affinity constant (KD) of at least about 40 pM as determined by surface plasmon resonance.Type: GrantFiled: December 20, 2017Date of Patent: September 7, 2021Assignee: CEPHALON, INC.Inventors: Mark Terence Liddament, Anthony Doyle, Adam Clarke, David Jose Simon Laine, Bridget Ann Cooksey
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Patent number: 11083925Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example, build muscle strength and/or reduce muscle tremors.Type: GrantFiled: March 9, 2018Date of Patent: August 10, 2021Assignee: LACEUP ATHLETICS LLCInventors: Jay Ciccarone, Anthony Doyle, Jr.
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Publication number: 20200102364Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.Type: ApplicationFiled: December 11, 2019Publication date: April 2, 2020Inventors: Collette Behrens, Anthony Doyle, Adam Clarke, Matthew Pollard, Teresa Domagala
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Publication number: 20200040089Abstract: Disclosed herein are human antibody molecules that immunospecifically bind to human CXCR2. The disclosed human antibody molecules are potent and selective antagonists of CXCR2 functions and prevent the recruitment of neutrophils into tissues without strongly depleting circulating neutrophil numbers. Pharmaceutical compositions, nucleic acid molecules, vectors, cells, and uses of the disclosed antibodies are also provided.Type: ApplicationFiled: July 31, 2019Publication date: February 6, 2020Inventors: Doris Shim Siew Chen, Lynn Dorothy Poulton, Adam Clarke, David Jose Simon Laine, Matthew Pollard, Bridget Ann Cooksey, Anthony Doyle, Jason William Gill
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Patent number: 10544199Abstract: The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon ? 2b (IFN?2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFN?2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFN?2b.Type: GrantFiled: October 23, 2015Date of Patent: January 28, 2020Assignee: Teva Pharmaceuticals Australia Pty LtdInventors: Collette Behrens, Anthony Doyle, Adam Clarke, Matthew Pollard, Teresa Domagala
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Publication number: 20180256935Abstract: This invention relates generally to a muscle activating and exercising device and a method of activating and exercising muscles of the human body. More particularly, it relates to an elongated device that is pliable enough to be wrapped around an object. Such device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis rack). The present invention also relates to a method of activating muscles using a pliable device. Through such a method, a user can, for example. build muscle strength and/or reduce muscle tremors.Type: ApplicationFiled: March 13, 2017Publication date: September 13, 2018Inventors: JAY CICCARONE, ANTHONY A. DOYLE, JR.
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Publication number: 20180256934Abstract: A muscle activating and exercising device and a method of activating and exercising muscles of the human body. The device includes an outer material and at least one flexible inner material. The device is an elongated device that is pliable enough to be wrapped around an object. The device also has an outer surface that creates a frictional fit between the device and the wrapped object. The wrapped object could be, for example, a wrist or ankle on a human limb or a location on a portion of sports equipment (e.g., a lacrosse stick, baseball bat, hockey stick, golf club or tennis racket). The method includes a method of activating muscles using the device. Through such a method, a user can, for example, build muscle strength and/or reduce muscle tremors.Type: ApplicationFiled: March 9, 2018Publication date: September 13, 2018Applicant: LacedUp Athletics LLCInventors: Jay Ciccarone, Anthony Doyle, JR.
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Publication number: 20180186873Abstract: Disclosed herein are fully human antibody molecules that immunospecifically bind to human IL-5. The antibody molecules can bind to human IL-5 with an equilibrium affinity constant (KD) of at least about 40 pM as determined by surface plasmon resonance.Type: ApplicationFiled: December 20, 2017Publication date: July 5, 2018Inventors: Mark Terence Liddament, Anthony Doyle, Adam Clarke, David Jose Simon Laine, Bridget Ann Cooksey
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Patent number: 9674906Abstract: A dimmer switch for an LED light source utilizes a thyristor-type device (“TTD”) having a first terminal, a second terminal, and a gate terminal. A low-voltage power supply converts alternating voltage into a direct voltage and is connected in parallel with the TTD. Gate current supplying circuitry is provided to supply current to the gate of the TTD, the gate current supplying circuitry powered by the low-voltage power supply and including a variable input device operable to vary a voltage waveform at the gate of the TTD in order to vary a voltage waveform provided at the second terminal.Type: GrantFiled: January 26, 2016Date of Patent: June 6, 2017Assignee: Lily Digital LLPInventor: Anthony Doyle
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Publication number: 20160213190Abstract: This invention relates to an insulated article. The insulated articles comprise either a twin walled construction and/or a protective pouch of packaging material encompassing a layer of insulating material. The insulating material comprises an aerogel material such as silica aerogel material and the function of the insulation is to minimize energy usage in the articles. One particularly preferred article is an oven constructed with an inner and an outer wall and a layer of aerogel insulation encapsulated in a packaging material therebetween. A transparent insulation may be used for the front door of the oven or alternatively a camera capturing images inside the oven may be provided in conjunction with a visual display for displaying the images captured by the camera. The energy consumption of the oven is reduced significantly. Similar techniques can also be applied to other articles of manufacture including hot water cylinders, beverage and food containers, radiators and fireplace surrounds to name a few.Type: ApplicationFiled: April 25, 2014Publication date: July 28, 2016Inventors: Anthony Doyle, David Doherty