Abstract: An in-the-wall wet-wipe dispenser comprises a water-tight container with a stack of pre-moistened wet-wipes therein. The container may be any shape, including rectangular or cylindrical. The distal end of the container is inserted through a hole in the sheet-rock and into the void behind the sheet-rock. When the container is secured in place, the opening of the container extends slightly out of the hole in the wall, or is at least proximate to the hole in the sheetrock. A flexible diaphragm with an iris (opening) advantageously covers the opening of the container. A front panel with a trap door conceals the hole in the wall. The trap-door conceals an extraction portal, which may include a hole in the front panel, the iris, or both. A tissue is withdrawn from the container through an extraction portal. When the trap door is closed, it inhibits evaporation of moisture from the container.