Patents by Inventor Anthony F. Heald

Anthony F. Heald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazolopyridine compounds, and intermediates, useful as anxiolytic agents
    Patent number: 4645838
    Abstract: Compounds of the formula (I): ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.7 and R.sup.8 are as described herein, D is oxygen, n is 1 or 2 and the physiologically acceptable salts thereof useful in reducing anxiety in an animal such as man. The compounds are potent anxiolytics having reduced side effects compared to known anxiolytics. Also pharmaceutical compositions, intermediates and methods of treatment and synthesis are described.
    Type: Grant
    Filed: June 25, 1984
    Date of Patent: February 24, 1987
    Assignee: ICI Americas Inc.
    Inventors: Thomas M. Bare, Anthony F. Heald
  • CNS-Depressant pyrazolopyridines
    Patent number: 4511568
    Abstract: Compounds of the formula (I): ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.7 and R.sup.8 are as described herein, D is oxygen or NR.sup.6, n is 1 or 2 and the physiologically acceptable salts thereof useful in reducing anxiety in an animal such as man. The compounds are potent anxiolytics having reduced side effects compared to known anxiolytics. Also pharmaceutical compositions, intermediates and methods of treatment and synthesis are described.
    Type: Grant
    Filed: April 15, 1983
    Date of Patent: April 16, 1985
    Assignee: ICI Americas Inc.
    Inventors: Thomas M. Bare, Anthony F. Heald
  • Nitrobenzofuran derivatives
    Patent number: 4469870
    Abstract: Nitrobenzofurazan derivatives having the formula ##STR1## are provided wherein R.sub.1 and R.sub.2 each is hydrogen, lower alkyl or phenyl-lower alkyl; R.sub.3 is hydrogen, hydroxy or lower alkyl; R.sub.4 is hydrogen or lower alkyl; m is 2 or 3; and n is 0, 1 or 2; these compounds are useful analytical tools.
    Type: Grant
    Filed: April 28, 1983
    Date of Patent: September 4, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Callixtus E. Ita, Anthony F. Heald, Peter Egli
  • Nitrobenzofurazan derivatives
    Patent number: 4395556
    Abstract: Nitrobenzofurazan derivatives having the formula ##STR1## are provided wherein R.sub.1 and R.sub.2 each is hydrogen, lower alkyl or phenyl-lower alkyl; R.sub.3 is hydrogen, hydroxy or lower alkyl; R.sub.4 is hydrogen or lower alkyl; m is 2 or 3; and n is 0, 1 or 2; these compounds are useful analytical tools.
    Type: Grant
    Filed: February 4, 1982
    Date of Patent: July 26, 1983
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Callixtus E. Ita, Anthony F. Heald, Peter Egli
  • Pyrazolo[3,4-b]pyridine compounds
    Patent number: 4364948
    Abstract: Certain pyrazolo[3,4-b]pyridine compounds which are useful for their activity in the central nervous system of warm-blooded animals, of the following formula (I) ##STR1## wherein R.sub.1 is lower alkyl;R.sub.a is hydrogen and R.sub.b is hydroxy or R.sub.a and R.sub.b combine to form a .dbd.O group;R.sub.5 is hydrogen or lower alkyl; andR.sub.6 is lower alkyl,and the pharmaceutically-acceptable salts thereof.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: December 21, 1982
    Assignee: ICI Americas Inc.
    Inventors: Anthony F. Heald, Richard A. Wildonger