Patents by Inventor Anthony Fallon

Anthony Fallon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human tissue plasminogen activator analogue having substitutions at amino acid positions 66, 67 and 68
    Patent number: 5232847
    Abstract: Tissue plasminogen activator (t-PA) analogues have at least one substitution in the growth factor (GF) domain that at least partially reduces hepatic receptor binding without substantially jeopardising physico-chemical stability in blood or fibrinolytic activity. This results in a longer plasma half life. Substitutions in the beta-sheet encompassing residues 63-72, especially at Leu 66 and/or Tyr 67 and/or Phe 68, are particularly preferred.
    Type: Grant
    Filed: December 11, 1990
    Date of Patent: August 3, 1993
    Assignee: British Bio-Technology Limited
    Inventors: Richard M. Edwards, Keith Dawson, Anthony Fallon, Stewart Craig