Patents by Inventor Anthony G. CHRISTODOULOU

Anthony G. CHRISTODOULOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240353513
    Abstract: A method of non-invasively assessing mitochondrial function in live tissue of a subject includes providing periodic hypoxia challenges to the subject during a cyclic oxygenation period, acquiring 4D BOLD fMRI data from the live tissue of the subject during the cyclic oxygenation period, and analyzing the acquired 4D BOLD fMRI data to determine a measure of mitochondrial function for each of a number of regions of the live tissue. Also, a system for non-invasively assessing mitochondrial function includes an fMRI system including a magnet, an RF system and a controller, wherein the controller is structured and configured to acquire 4D BOLD fMRI data from the live tissue of the subject during a cyclic oxygenation period wherein periodic hypoxia challenges are experienced by the subject, and analyze the acquired 4D BOLD fMRI data to determine a measure of mitochondrial function for each of a number of regions of the live tissue.
    Type: Application
    Filed: April 16, 2024
    Publication date: October 24, 2024
    Applicants: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, CEDARS-SINAI MEDICAL CENTER
    Inventors: Yijen Wu, Anthony G. Christodoulou, Devin Raine Everaldo Cortes
  • Patent number: 10436871
    Abstract: A new low rank tensor (LRT) imaging strategy/methodology, specifically for quantitative cardiovascular magnetic resonance (CMR) multitasking, includes performing a low-rank tensor image model exploiting image correlation along multiple physiological and physical time dimensions, a non-ECG data acquisition strategy featuring minimal gaps in acquisition and frequent collection of auxiliary subspace training data, and a factored tensor reconstruction approach which enforces the LRT model.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: October 8, 2019
    Assignee: CEDARS-SINAI MEDICAL CENTER
    Inventors: Debiao Li, Anthony G. Christodoulou, Jaime Shaw, Yibin Xie, Christopher Nguyen
  • Publication number: 20180306882
    Abstract: A new low rank tensor (LRT) imaging strategy/methodology, specifically for quantitative cardiovascular magnetic resonance (CMR) multitasking, includes performing a low-rank tensor image model exploiting image correlation along multiple physiological and physical time dimensions, a non-ECG data acquisition strategy featuring minimal gaps in acquisition and frequent collection of auxiliary subspace training data, and a factored tensor reconstruction approach which enforces the LRT model.
    Type: Application
    Filed: April 24, 2017
    Publication date: October 25, 2018
    Inventors: Debiao LI, Anthony G. CHRISTODOULOU, Jaime SHAW, Yibin XIE, Christopher NGUYEN