Abstract: A method of producing blood plasma useful in the treatment of a virus causing a viral infection characterized by an uncontrolled release of proinflammatory cytokines in a human affected by the viral infection comprises the following steps: adding a quantity of sodium citrate to a tube; delivering a blood collected from a human donor having antibodies to the virus to the tube; incubating the blood at a temperature of about 37° C. for about 6 hours to about 24 hours; centrifuging the blood to separate the blood into a plasma component and a cellular fraction; and collecting the plasma component. The plasma component can be administered to patient infected with a virus causing a viral infection characterized by an uncontrolled release of proinflammatory cytokines.

Abstract: Described are methods of producing an autologous composition useful for treatment of damaged and/or injured connective tissues, chronic tendinosis, chronic muscle tears and/or chronic degenerative joint conditions and skin inflammatory disorders in a mammal. The method comprises preparing an anti-inflammatory/anti-catabolic component of the autologous composition comprising IL-1ra and TIMPs. An anti-inflammatory/anti-catabolic component is prepared comprising: collecting blood from the mammal; delivering the blood to a tube; incubating the blood at a temperature of from about 37° C. to about 39° C. for about 24 hours, preferably in the presence of sodium citrate; centrifuging the blood to separate the blood into a supernatant component and a cellular fraction; and collecting the supernatant component.

Abstract: Described are methods of producing an autologous composition useful for treatment of damaged and/or injured connective tissues, chronic tendinosis, chronic muscle tears and/or chronic degenerative joint conditions and skin inflammatory disorders in a mammal. The method comprises preparing an anti-inflammatory/anti-catabolic component of the autologous composition comprising IL-1ra and TIMPs. An anti-inflammatory/anti-catabolic component is prepared comprising: collecting blood from the mammal; delivering the blood to a tube; incubating the blood at a temperature of from about 37° C. to about 39° C. for about 24 hours, preferably in the presence of sodium citrate; centrifuging the blood to separate the blood into a supernatant component and a cellular fraction; and collecting the supernatant component.

Abstract: A method of producing an autologous anti-inflammatory/anti-catabolic autologous composition useful in the treatment of a mammal suffering from damaged and/or injured connective tissues, chronic tendinosis, chronic muscle tears, chronic degenerative joint conditions, and/or skin inflammatory disorders is provided. The method comprising the following steps: delivering a blood collected from the mammal to a tube; storing the blood in presence of sodium citrate at a temperature of from about 20° C. to about 40° C. for at least about 3.5 hours; centrifuging the blood to separate the blood into a supernatant component and a cellular fraction; and collecting the supernatant component.

Abstract: Described are methods of producing an autologous composition useful for treatment of damaged and/or injured connective tissues, chronic tendinosis, chronic muscle tears and/or chronic degenerative joint conditions and skin inflammatory disorders in a mammal. The method comprises preparing an anti-inflammatory/anti-catabolic component of the autologous composition comprising IL-1ra and TIMPs. An anti-inflammatory/anti-catabolic component is prepared comprising: collecting blood from the mammal; delivering the blood to a tube; incubating the blood at a temperature of from about 37° C. to about 39° C. for about 24 hours, preferably in the presence of sodium citrate; centrifuging the blood to separate the blood into a supernatant component and a cellular fraction; and collecting the supernatant component.

Abstract: Described are methods of producing an autologous composition useful for treatment of damaged and/or injured connective tissues, chronic tendinosis, chronic muscle tears and/or chronic degenerative joint conditions and skin inflammatory disorders in a mammal. The method comprises preparing an anti-inflammatory/anti-catabolic component of the autologous composition comprising IL-1ra and TIMPs. An anti-inflammatory/anti-catabolic component is prepared comprising: collecting blood from the mammal; delivering the blood to a tube; incubating the blood at a temperature of from about 37° C. to about 39° C. for about 24 hours, preferably in the presence of sodium citrate; centrifuging the blood to separate the blood into a supernatant component and a cellular fraction; and collecting the supernatant component.

Abstract: A stretch film roll comprises a wound stretch film web section having longitudinal edges that are non-linear, where the stretch film roll comprises a cylindrical central portion and tapered end portions.

Abstract: Described is a method of producing a storage stable autologous composition comprising regenerative growth factors and cytokines obtained from platelets. The method comprises the steps of collecting or providing blood from a mammal; delivering the blood to a receptacle; centrifuging the blood to separate a platelet rich plasma component from the blood; collecting the platelet rich plasma component; passing the platelet rich plasma component through a small pore filter to produce the storage stable autologous composition comprising regenerative growth factors and cytokines derived from platelets; and collecting the storage stable autologous composition. The storage stable autologous composition retains regenerative biological activity for up to at least nine months when stored in a frozen state. Also described is a storage stable autologous composition comprising regenerative growth factors and cytokines obtained from platelets produced by the method as described.

Abstract: A stretch film roll comprises a wound stretch film web section having longitudinal edges that are non-linear, where the stretch film roll comprises a cylindrical central portion and tapered end portions.

Abstract: A method for producing a roll of stretch film comprises the steps of passing a stretch film web over a first roller, and winding the stretch film web around a second roller against the first roller, where the first roller has a surface for enabling the introduction of air into the wound stretch film web.

Abstract: An apparatus for fabricating a stretch film roll includes a device configured to fold a stretch film web to yield a folded stretch film web comprising at least one longitudinal band of increased thickness, with each band of increased thickness being spaced from the longitudinal edges of the folded stretch film web, and a driven winding shaft for winding the folded stretch film web.

Abstract: Described are methods of producing an autologous composition useful for treatment of damaged and/or injured connective tissues, chronic tendinosis, chronic muscle tears and/or chronic degenerative joint conditions and skin inflammatory disorders in a mammal. The method comprises preparing an anti-inflammatory/anti-catabolic component of the autologous composition comprising IL-1ra and TIMPs. An anti-inflammatory/anti-catabolic component is prepared comprising: collecting blood from the mammal; delivering the blood to a tube; incubating the blood at a temperature of from about 37° C. to about 39° C. for about 24 hours, preferably in the presence of sodium citrate; centrifuging the blood to separate the blood into a supernatant component and a cellular fraction; and collecting the supernatant component.

Abstract: An apparatus for fabricating a stretch film roll includes a device configured to fold a stretch film web to yield a folded stretch film web comprising at least one longitudinal band of increased thickness, with each band of increased thickness being spaced from the longitudinal edges of the folded stretch film web, and a driven winding shaft for winding the folded stretch film web.

Abstract: An apparatus for fabricating a stretch film roll comprises a device configured to fold a stretch film web to yield a folded stretch film web comprising at least one longitudinal band of increased thickness, with each band of increased thickness being spaced from the longitudinal edges of the folded stretch film web, and a driven winding shaft for winding the folded stretch film web.

Abstract: An apparatus for fabricating a stretch film roll comprises a device configured to fold a stretch film web to yield a folded stretch film web comprising at least one longitudinal band of increased thickness, with each band of increased thickness being spaced from the longitudinal edges of the folded stretch film web, and a driven winding shaft for winding the folded stretch film web.

Abstract: An apparatus for fabricating stretch film rolls comprises a first plurality of cutting blades configured to be oscillated, and a second plurality of cutting blades configured to be oscillated independently of the first plurality of cutting blades. The first and second pluralities of cutting blades are configured for cutting a stretch film web into one or more stretch film web sections each having at least one non-linear longitudinal edge. The apparatus also comprises a driven winding shaft for winding the one or more stretch film web sections.

Abstract: An apparatus for fabricating stretch film rolls comprises a plurality of cutting blades for cutting a stretch film web into one or more stretch film web sections, the plurality of cutting blades being configured to be oscillated. The apparatus also comprises a driven winding shaft for winding the one or more stretch film web sections.

Abstract: A method for producing a roll of stretch film comprises the steps of passing a stretch film web over a first roller, and winding the stretch film web around a second roller against the first roller, where the first roller has a surface for enabling the introduction of air into the wound stretch film web.