Abstract: The disclosure provides TNF-like ligand 1a (TL1a)-binding proteins comprising an antigen binding domain of an antibody which binds specifically to TL1a and inhibits interaction of TL1a and Death Receptor 3 (DR3) and which does not inhibit the interaction of TL1a and Decoy Receptor 3 (DcR3). The disclosure also provides uses of the TL1a-binding proteins.

Abstract: In one or more embodiments, one or more systems, one or more methods, and/or one or more processes may receive a scaling factor and a retention time power law coefficient associated with a solid state drive (SSD); determine a first raw bit error rate (RBER) value for the SSD at a first time; extrapolate a second time at which a second RBER value for the SSD would reach a maximum RBER value if left unpowered, based at least on the first raw bit error rate value, the scaling factor, and the retention time power law coefficient; and provide the second time at which the second RBER value for the SSD would reach the maximum raw bit error rate value if left unpowered to at least one of an information handling system (IHS), IHS firmware, a baseboard management controller of the IHS, and an application executing on the IHS.

Abstract: A storage device write-read error reduction system includes a computing device that includes a storage device. The storage device determines, at a temperature that is within a predefined temperature range, that a storage device background operation should be performed and, in response, identifies data that is stored in the storage device and that was written to the storage device outside the predefined temperature range. The storage device then prioritizes the data that was written to the storage device outside the predefined temperature range over data that was written to the storage device within the predefined temperature range and, based on that prioritization, performs the storage device background operation to rewrite the data to the storage device.

Abstract: A storage device self-heating system includes a storage device having a processing system, a storage subsystem, and at least one heat transfer subsystem coupled between the processing system and the storage subsystem. The storage device determines that a temperature of the storage subsystem is below a temperature threshold and, in response, uses the processing system to perform a plurality of computations that are configured to generate an amount of heat that, when transferred via the heat transfer subsystem(s), raises the temperature of the storage subsystem. The heat transfer subsystem(s) transfer heat generated via the performance of the plurality of computations to the storage subsystem, and when the storage device determines that the temperature of the storage subsystem is above the temperature threshold, it performs at least one storage operation.

Abstract: A method and a system for noise discrimination, the method comprising measuring noise levels of a noise source, measuring noise levels at a target location positioned at a distance from the noise source, measuring wind speed and direction in an area comprising the noise source and the target location, filtering transient short-duration events from the noise levels measured at the noise source, yielding filtered noise levels of the noise source, filtering transient short-duration events from the noise levels measured at the target location, yielding filtered noise levels of the target location, measuring a sound transfer function between the noise source and the target location using the filtered noise levels, comparing the measured sound transfer function with a reference transfer function; and when the difference between the measured transfer function and the reference transfer function is above a predetermined threshold, determining a probability that noise at the location originates from the noise source.

Abstract: Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein-1 (hPD-1), and immunoconjugates comprising the same.

Abstract: A storage device projected temperature environment configuration system includes storage devices with the same physical hardware configuration, and a computing device manufacturing system that manufactures computing devices.

Abstract: A storage device projected temperature environment configuration system includes storage devices with the same physical hardware configuration, and a computing device manufacturing system that manufactures computing devices.

Abstract: A screen retraction mechanism for a retractable screen assembly, the screen retraction mechanism comprising: a roller housing; a roller spinably mounted within the roller housing and for rolling a screen material sheet thereon; a torsion spring coupled to the roller for rotationally biasing the roller; and a tension adjuster coupled to an end of the torsion spring and configured to move in and out of engagement with the roller housing, wherein the tension adjuster is spinnable to selectably tension the torsion spring when out of engagement with the roller housing.

Abstract: A dewar includes two coaxial openings of different sizes (e.g., to allow for interfacing with a Stirling cryocooler and a Stirling generator), a polytetrafluoroethylene or glass inner chamber (e.g., to reduce conductive heat transfer, particularly through the dewar neck), and an integrated, annular desiccant ring (e.g., for drying low-pressure, ambient air).

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human PAR-2 and compositions comprising such antibodies or antigen-binding fragments thereof. In a particular aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human PAR-2 block the interaction between a PAR-2 activating ligand and an extracellular domain of PAR-2, and/or blocks PAR-2 activation by a PAR-2 activating ligand, In further aspects, the antibodies or antigen-binding fragments can be used to treat diseases or conditions associated with increased expression of PAR-2 and/or diseases or conditions that can be alleviated by antagonizing activation of PAR-2 by a PAR-2 activating ligand (e.g., airway diseases, skin diseases, cancer, orofacial granulomatosis, inflammatory conditions, and pain associated with various diseases or conditions).

Abstract: An electronic protection system includes an electronic protection IC, mains power lines including a line rail and a neutral rail, a power switch, and a current sense device. A load is coupled with the mains power lines via the power switch and the current sense device. The electronic protection circuit turns off the power switch within eighty (80) milliseconds from a zero crossing in power delivered by the mains power lines when a load current is too high. A dummy DAC supplies a dummy current to prevent instability resulting from positive feedback during a change between a first state and a second state. The system may include an overcurrent detection circuit with a sense input, a comparator, a latch, and a pulse generator, configured to output a train of pulses with a low duty cycle when a current amplitude exceeds a reference value.

Abstract: The present disclosure generally relates to anti-PACAP antibodies, pharmaceutical compositions comprising such antibodies, and methods of producing and using such antibodies.

Abstract: The invention relates to a liquid air energy storage system. The storage system includes a cryocooler, a dewar, and a Sterling engine. The cryocooler cools a tip of a cold head to cryogenic temperatures, the cryocooler further includes a heat sink to reject heat from the cryocooler and a cold head that protrudes into a dewar through a cryocooler cavity, the cold head to condense ambient air to create liquified air in the dewar. The dewar holds the liquified air at low temperatures, the dewar having the cryocooler cavity and a Stirling cavity. The Stirling engine drives an electric generator, the Stirling engine further including a cold finger protruding into the dewar through the Stirling cavity, the cold finger to move the liquified air from the dewar to a Stirling heat sink; the Stirling heat sink to expand the liquified air; and the electric generator to generate output electricity.

Abstract: A system, a method and an autonomous network for vibration monitoring, the system comprising a master station preset for recording vibrations at a master trigger threshold; a secondary station, the secondary station and the master station being time synchronized, a server in communication with the master and secondary stations; wherein, the master station is configured to transmit a master trig time to the server and to start recording vibrations when the master trigger threshold is exceeded; the server is configured to store the master trig time; the secondary station is configured to detect the master trig time stored by the server, and upon detecting the master trig time, to record vibrations; and wherein the master and secondary stations are configured to transmit respective recorded vibrations to the server and the server is configured to classify the recorded vibrations in relation to a preset seismic threshold.

Abstract: A protection IC protects an external load connected to mains supply lines from dangerous or undesired conditions such as overvoltage, undervoltage, and overcurrent, by disconnecting the external load for at least the duration of such a condition. The IC has a range detector, a zero-crossing detector, a control unit, a switch driver, and a dummy DAC. The range detector senses the presence of an unwanted condition. The control unit then waits for a zero crossing, upon which it disconnects the load. A lockout timer may introduce a minimum wait time before reconnecting the load. To prevent instabilities around the switching points, hysteresis in the window thresholds prevents impact from noise. The dummy DAC regulates a dummy current that linearizes the IC's current consumption around the switching points to prevent instabilities caused by positive feedback in non-linear transitions.

Abstract: A brake arrangement, for a retractable screen arrangement in which the a screen roller applies a retraction force to the screen and brake arrangement, includes a brake arrangement, for providing a braking force between the brake arrangement and a track which guides the brake arrangement, to resist retraction. The brake arrangement provides a brake member with a friction surface for contacting the bearing surface; a brake member support for supporting the brake member; and a forcing arrangement for forcing the friction surface against the bearing surface. The forcing arrangement includes a biasing arrangement for biasing the friction surface onto the bearing surface, and a force-increasing arrangement for increasing the force with which the friction surface engages the bearing surface. The force increasing arrangement converts a frictional force between the friction surface and the track into additional contact pressure force of the friction surface onto the guide track.

Abstract: In one or more embodiments, one or more systems, one or more methods, and/or one or more processes may receive a scaling factor and a retention time power law coefficient associated with a solid state drive (SSD); determine a first raw bit error rate (RBER) value for the SSD at a first time; extrapolate a second time at which a second RBER value for the SSD would reach a maximum RBER value if left unpowered, based at least on the first raw bit error rate value, the scaling factor, and the retention time power law coefficient; and provide the second time at which the second RBER value for the SSD would reach the maximum raw bit error rate value if left unpowered to at least one of an information handling system (IHS), IHS firmware, a baseboard management controller of the IHS, and an application executing on the IHS.

Abstract: A protection IC protects an external load connected to mains supply lines from dangerous or undesired conditions such as overvoltage, undervoltage, and overcurrent, by disconnecting the external load for at least the duration of such a condition. The IC has a range detector, a zero-crossing detector, a control unit, a switch driver, and a dummy DAC. The range detector senses the presence of an unwanted condition. The control unit then waits for a zero crossing, upon which it disconnects the load. A lockout timer may introduce a minimum wait time before reconnecting the load. To prevent instabilities around the switching points, hysteresis in the window thresholds prevents impact from noise. The dummy DAC regulates a dummy current that linearizes the IC's current consumption around the switching points to prevent instabilities caused by positive feedback in non-linear transitions.

Abstract: Recombinant antibodies that specifically bind to IL-15 as well as a complex of IL-15 and the IL-15 Receptor-alpha are provided. The antibodies inhibit immune cell proliferation, and are capable of use in the treatment of any autoimmune or inflammatory disease or condition where IL-15 is dysregulated, including Celiac disease.