Abstract: A novel gene PGC-3, and its role in regulating the transcriptional activity of PPAR? in adipose tissue. PGC-3 is highly expressed in human white adipose tissue and has utility in the development of new therapeutic agents for use in the treatment of obesity and other related disorders such as non-insulin dependent diabetes mellitus, insulin resistance syndrome, dyslipidemia, and atherosclerosis.

Abstract: A safety razor has a handle and a cartridge selectively detachable from the handle. The cartridge has at least one blade with a sharp cutting edge and a beginning shaving utility. A connecting is coupled to the handle for attaching or detaching the cartridge from the handle in response to an action. The safety razor includes a sensor that generates a signal in response to the action.

Abstract: A powered wet razor has a handle and a cartridge selectively detachable from the handle. The cartridge has at least one blade with a sharp cutting edge and is characterized by an expected shaving utility. An electrical arrangement that detects and tracks utility of the razor and determines a remaining shaving utility based on the expected utility and the tracked utility. The razor includes an indicator for providing a remaining shaving utility signal to a user.

Abstract: A safety razor has a handle and a cartridge selectively detachable from the handle. The cartridge has at least one blade with a sharp cutting edge and an expected shaving utility. A connecting structure is coupled to the handle and attaches or detaches the cartridge from the handle in response to a detachment action performed by a user. A detector within the handle has an actuator coupled to the connecting structure and a sensor for generating a signal, wherein the actuator applies an action on the sensor during the action and the sensor generates the signal in response to the action.

Abstract: A safety razor has a blade unit having at least one blade with a sharp cutting edge. A dielectric handle is configured to carry the blade unit and a conductive ground member is disposed within the handle. The safety razor has an electrically operated device. An electrical arrangement having a sensor electrically coupled to the blade unit and the ground member senses skin contact with the blade unit and actuates the device based on the sensing.

Abstract: A novel gene PGC-3, and its role in regulating the transcriptional activity of PPAR? in adipose tissue. PGC-3 is highly expressed in human white adipose tissue and has utility in the development of new therapeutic agents for use in the treatment of obesity and other related disorders such as non-insulin dependent diabetes mellitus, insulin resistance syndrome, dyslipidemia, and atherosclerosis.

Abstract: The present invention provides a composition for treating a bacterial biofilm, comprising a first bacteriophage that is capable of infecting a bacterium within said biofilm, and a first polysaccharide lyase enzyme that is capable of degrading a polysaccharide within said biofilm. The composition preferably further comprises a pharmaceutically-acceptable antimicrobial agent, and may also include a DNase. Also provided are modified bacteriophages, methods of creating modified bacteriophages, use of said compositions and bacteriophage for treating biofilms, and methods for treating biofilms using the bacteriophages and compositions of the invention.

Abstract: The use of the G protein coupled receptor GPR56 to identify appetite control agents and diagnostic agents.

Abstract: The use of the G protein coupled receptor GPR3 to identify appetite control agents and diagnostic agents.

Abstract: A gene PGC-3 PPAR gamma coactivator-3, and it's role in regulating the transcriptional activity of peroxisome proliferator activated receptor-Y PPAR-Y in adipose tissue. PGC-3 is highly expressed in human white adipose tissue and has utility in the development of new therapeutic agents for use in the treatement of obesity and other related disorders such as non-insulin dependent diabetes mellitus, insulin resistance syndrome, dyslipidemia, and atherosclerosis.

Abstract: The use of the G protein coupled receptor GPR22 to identify appetite control agents and diagnostic agents.

Abstract: The use of the G protein coupled receptor GPR3 to identify appetite control agents and diagnostic agents.

Abstract: The use of the G protein coupled receptor GPR56 to identify appetite control agents and diagnostic agents.

Abstract: Methods for preserving micro-organisms including viruses, such that infectivity is retained, are provided, as well as the use of such methods in preparing e.g. vaccines.