Abstract: A rugged, ergonomic integrated telecommunications handset includes an electronic controller that interoperates and controls the universal remote control (URC), which connects to multiple radios simultaneously. The controller downloads options which are implemented by the controller. The handset has an ability to vibrate in a silent mode, and has a memory capacity, as well as GPS capacity. Ergonomically, the handset has a pair of side arrays of protruding ribs, which enhance gripping, preventing the handset from falling out of the user's hands, even if the user has gloves on in inclement weather conditions in the field. While compatible with the latest radio system software defined dual net and dual channel radio equipment, the handset is also backward compatible with single radios or with two or more separate radios, and may communicate using Bluetooth.

Abstract: Provided are peptides, and conjugates comprising targeting peptides and payloads. The peptides comprise a plurality of modules corresponding to at least one of module 1, module 2, or module 3 of the collagen binding domain of a gelatinase, or a gelatin-binding fragment or variant thereof. The gelatinase may be MMP-2. The conjugates may be therapeutic or non-therapeutic. Medical uses of the peptides or therapeutic conjugates, and pharmaceutical compositions comprising these, are also provided, as are nucleic acids encoding the peptides.