Patents by Inventor Anthony Hollingsworth
Anthony Hollingsworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220258937Abstract: A packaging includes a composite material. The composite material includes a barrier layer and a backing layer. The backing layer includes a spunbonded nonwoven, arranged on at least one side of the barrier layer and bonded to the barrier layer by heat and pressure. The barrier layer includes a nonwoven containing 1 to 70 wt % melt-blown fibers and 30 to 99 wt % staple fibers, relative to a total weight of the nonwoven in each case.Type: ApplicationFiled: February 3, 2022Publication date: August 18, 2022Inventors: Johanna Spoerl, Arun Prasad Venugopal, Klaus-Dietmar Wagner, Anthony Hollingsworth, Michaela Rau, Alexander Kolew, Naotaka Kimura
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Patent number: 10023652Abstract: The present disclosure relates to a method of inhibiting tumor growth. More specifically, the present disclosure relates to the use of monoclonal antibodies for targeting truncated O-glycans on glycoproteins to inhibit activation of pro-survival ceil signaling pathways, to inhibit tumor growth. For example, monoclonal antibody AR9.6 may be used to target truncated O-glycans on the MUC16 glycoprotein, thereby inhibiting the phosphatidyiinositol 3-kinase/Akt (Pi3K/Akt) signaling pathway.Type: GrantFiled: June 24, 2014Date of Patent: July 17, 2018Assignee: Board of Regents of the University of NebraskaInventors: Michael Anthony Hollingsworth, Prakash Radhakrishnan
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Publication number: 20160376376Abstract: The present disclosure relates to a method of inhibiting tumor growth. More specifically, the present disclosure relates to the use of monoclonal antibodies for targeting truncated O-glycans on glycoproteins to inhibit activation of pro-survival ceil signaling pathways, to inhibit tumor growth. For example, monoclonal antibody AR9.6 may be used to target truncated O-glycans on the MUC16 glycoprotein, thereby inhibiting the phosphatidyiinositol 3-kinase/Akt (Pi3K/Akt) signaling pathway.Type: ApplicationFiled: June 24, 2014Publication date: December 29, 2016Inventors: Michael Anthony Hollingsworth, Prakash Radhakrishnan
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Patent number: 9180394Abstract: The invention relates to a multi-layer composite for use in an air filter, comprising at least one upstream ply and a support ply that is connected to the upstream ply. The upstream ply is made of a non-woven fabric and has a finer porosity than the support ply. The aim of the invention is to form and further develop a multi-layer composite for use in an air filter, in particular in a filter bag in such a manner that the upstream ply can be connected in a stable and economical manner to the support ply. The invention is characterised in that the upstream ply is embodied as a spun bonded non-woven, the continuous filaments of which are at least partially twisted or interwoven with the support ply.Type: GrantFiled: March 13, 2008Date of Patent: November 10, 2015Assignee: CARL FREUDENBERG KGInventors: Heiko Manstein, Robert Groten, Anthony Hollingsworth, Ingrid Ewald, Joachim Hendler, Klaus Veeser
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Patent number: 8653233Abstract: The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer.Type: GrantFiled: June 1, 2012Date of Patent: February 18, 2014Assignee: University of Nebraska Medical CenterInventors: Michael Anthony Hollingsworth, Karl Kohlgraf, Tom Caffrey
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Publication number: 20120270798Abstract: The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer.Type: ApplicationFiled: June 1, 2012Publication date: October 25, 2012Inventors: Michael Anthony Hollingsworth, Karl Kohlgraf, Tom Caffrey
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Patent number: 8193309Abstract: The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer.Type: GrantFiled: January 29, 2010Date of Patent: June 5, 2012Assignee: Board of Regents of the University of NebraskaInventors: Michael Anthony Hollingsworth, Karl Kohlgraf, Tom Caffrey
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Publication number: 20100190720Abstract: The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer.Type: ApplicationFiled: January 29, 2010Publication date: July 29, 2010Inventors: Michael Anthony Hollingsworth, Karl Kohlgraf, Tom Caffrey
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Publication number: 20100119794Abstract: The invention relates to a multi-layer composite for use in an air filter, comprising at least one upstream ply (1) and a support ply (2) that is connected to the upstream ply. The upstream ply (1) is made of a non-woven fabric and has a finer porosity than the support ply (2). The aim of the invention is to form and further develop a multi-layer composite for use in an air filter, in particular in a filter bag in such a manner that the upstream ply can be connected in a stable and economical manner to the support ply. Said invention is characterised in that the upstream ply (1) is embodied as a spun bonded non-woven, the continuous filaments (3) of which are at least partially twisted or interwoven with the support ply (2).Type: ApplicationFiled: March 13, 2008Publication date: May 13, 2010Applicant: CARL FREUDENBERG KGInventors: Heiko Manstein, Robert Groton, Anthony Hollingsworth, Ingrid Ewald
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Publication number: 20080227560Abstract: A practice putting device comprises a generally L-shaped housing adapted in use to lie in a first stake position on a generally flat horizontal. Surface over which a golf ball can be putted towards the device, with the rear of one limb of the housing in contact with the flat surface and the other limb pointing in generally upward direction. The upper surface of the one limb presents a ramp (14) up which a golf ball can roll on being putted towards the device. The position of the upper end of the ramp relative to the rear corner between the two limbs is such that the ramp, a turning moment (52) will be created about the said corner, causing the device to pivot like a see saw about the corner, which becomes a fulcrum (13).Type: ApplicationFiled: March 24, 2005Publication date: September 18, 2008Inventor: Sidney Anthony Hollingsworth Whitehouse
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Patent number: 6656400Abstract: A method for producing a pleated filter material from a nonwoven fabric having spacers for the pleated folds formed from the filter material itself, a formed fabric made of stretched synthetic fibers and thermoplastic and/or thermally cross-linked binding agent being heated in an oven to a temperature lying at least in the softening temperature range and/or the cross-linking temperature range of the binding agent, and subsequently, the formed fabric being formed between profiled calender rolls and cooled simultaneously.Type: GrantFiled: March 28, 2001Date of Patent: December 2, 2003Assignee: Firma Carl FreudenbergInventors: Klaus Veeser, Anthony Hollingsworth, Dirk Dantz
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Patent number: 6387141Abstract: An air filter having a depth filter material which includes a nonwoven fabric having a upstream side and a downstream side. The nonwoven fabric is formed of adhesively and/or cohesively bonded fibers, the fibers having intertwinements which are produced by liquid-jetting from the downstream side prior to the adhesive and/or cohesive bonding, and the fibers, because of the liquid-jetting, being compacted increasingly from the upstream side toward the downstream side in such a way that differently compacted regions are formed, in which particles of different size can be separated.Type: GrantFiled: September 21, 1999Date of Patent: May 14, 2002Assignee: Firma Carl FreudenbergInventors: Anthony Hollingsworth, Oliver Staudenmayer, Ralph Berkemann
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Publication number: 20010050136Abstract: A method for producing a pleated filter material from a nonwoven fabric having spacers for the pleated folds formed from the filter material itself, a formed fabric made of stretched synthetic fibers and thermoplastic and/or thermally cross-linked binding agent being heated in an oven to a temperature lying at least in the softening temperature range and/or the cross-linking temperature range of the binding agent, and subsequently, the formed fabric being formed between profiled calender rolls and cooled simultaneously.Type: ApplicationFiled: March 28, 2001Publication date: December 13, 2001Inventors: Klaus Veeser, Anthony Hollingsworth, Dirk Dantz
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Patent number: 6146436Abstract: A cartridge filter having a cylindrical filter element, which is pleated parallel to its axis and is made of a layered non-woven unitary fabric. The fabric is permeable by air flow in the radial direction and is used in fresh air-supply filtration with initial pressure losses of less than 300 Pa at air flow rates through the filter medium of less than 250 m.sup.3 /m.sup.2 h. The non-woven fabric has a mass per unit area of 100 to 500 g/m.sup.2, and a thickness of 1.5-7.0 mm mm. It is made of layered staple fibers of a titer of 0.1 to 50 decitex, which are bonded by a thermally softened binding agent. A bottom layer bordering on the downstream side is contained in the non-woven fabric, having a thickness of 10 to 60% of the overall thickness, and is compressed two to ten times as much as a top layer bordering on the upstream flow side having a thickness of 10-60% of the overall thickness. One or more intermediate layers link the top and bottom layers to one another.Type: GrantFiled: March 30, 1998Date of Patent: November 14, 2000Assignee: Firma Carl FreudenbergInventors: Anthony Hollingsworth, Peter Pfeuffer, Jorg Sievert, Thomas Schroth, Antje Rudolph
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Patent number: 5063101Abstract: Disclosed is a textile product and a method for making that product for a shirt or blouse interlining formed of a bonded base material having bonded thereon a fleece of adhesive fibers. A plurality of adhesive dots are applied on that surface of the fleece opposite to the surface bonded to the base material. The dots are substantially in a singular planar arrangement and, at least some of the dots, are separated from the base material by the fleece. The interlining can be fused to a shirt fabric such, as a broadcloth, to provide a good and smooth surface appearance. With the product of the invention, the smooth surface appearance is retained even after washing.Type: GrantFiled: December 23, 1988Date of Patent: November 5, 1991Assignee: Freudenberg Nonwovens Limited PartnershipInventors: Peter S. Grynaeus, Anthony Hollingsworth, Chester J. Petkiewicz
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Patent number: D539374Type: GrantFiled: October 24, 2005Date of Patent: March 27, 2007Inventor: Sidney Anthony Hollingsworth Whitehouse
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Patent number: D544555Type: GrantFiled: March 30, 2006Date of Patent: June 12, 2007Inventor: Sidney Anthony Hollingsworth Whitehouse
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Patent number: D545384Type: GrantFiled: October 24, 2005Date of Patent: June 26, 2007Inventor: Sidney Anthony Hollingsworth Whitehouse