Patents by Inventor Anthony Huxley

Anthony Huxley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-17A MODULATORS
    Publication number: 20230286943
    Abstract: The present invention relates to compounds that are IL-17A modulators. The compounds have the structural Formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with modulation of IL-17A activity.
    Type: Application
    Filed: May 25, 2021
    Publication date: September 14, 2023
    Inventors: Barrie Phillip MARTIN, Jan-Christoph WESTERMANN, Oliver Thomas KERN, Arthur Jonathan HOLMES, Angus MORRISON, Michael KICZUN, Mounir AL MASRI, Alasdair SMITH, Anthony HUXLEY
  • IL-17A MODULATORS
    Publication number: 20230227427
    Abstract: The present invention relates to compounds that are IL-17A modulators. The compounds have the structural Formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with modulation of IL-17A activity.
    Type: Application
    Filed: May 25, 2021
    Publication date: July 20, 2023
    Inventors: Barrie Phillip MARTIN, Jan-Christoph WESTERMANN, Oliver Thomas KERN, Arthur Jonathan HOLMES, Bohdan WASZKOWYCZ, Angus MORRISON, Michael KICZUN, Mounir AL MASRI, Alasdair SMITH, Anthony HUXLEY
  • Antibacterial compounds
    Patent number: 10385065
    Abstract: The invention relates to antibacterial and anti-mycobacterial drug compounds of formula I. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the derivatives in treating bacterial infections, and methods of treating bacterial infections. The invention is also directed to antibacterial drug compounds capable of treating bacterial infections that are currently hard to treat with existing drug compounds, e.g., those caused by resistant bacterial or mycobacterial strains.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: August 20, 2019
    Assignee: Redx Pharma PLC
    Inventors: Andrew Ratcliffe, Anthony Huxley, David Lyth, Gary Noonan, Ralph Kirk, Mario Uosis-Martin, Neil Stokes
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20170158708
    Abstract: The invention relates to antibacterial and anti-mycobacterial drug compounds of formula I. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the derivatives in treating bacterial infections, and methods of treating bacterial infections. The invention is also directed to antibacterial drug compounds capable of treating bacterial infections that are currently hard to treat with existing drug compounds, e.g., those caused by resistant bacterial or mycobacterial strains.
    Type: Application
    Filed: April 10, 2015
    Publication date: June 8, 2017
    Applicant: Redx Pharma PLC
    Inventors: Andrew Ratcliffe, Anthony Huxley, David Lyth, Gary Noonan, Ralph Kirk, Mario Uosis-Martin, Neil Stokes
  • 1-benzoyl substituted diazepine derivatives as selective histamine H3 receptor agonists
    Patent number: 8492375
    Abstract: The present invention relates to novel diazepanyl derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: July 23, 2013
    Assignee: Glaxo Group Limited
    Inventors: Gordon Bruton, Anthony Huxley, Barry Sidney Orlek, Kishore Kalidas Rana
  • 1-BENZOYL SUBSTITUTED DIAZEPINE DERIVATIVES AS SELECTIVE HISTAMINE H3 RECEPTOR AGONISTS
    Publication number: 20110039833
    Abstract: The present invention relates to novel diazepanyl derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: October 26, 2010
    Publication date: February 17, 2011
    Inventors: GORDON BRUTON, Anthony Huxley, Barry Sidney Orlek, Kishore Kalidas Rana
  • 1-benzoyl substituted diazepine derivatives as selective histamine H3 receptor agonists
    Patent number: 7846922
    Abstract: The present invention relates to novel diazepanyl derivatives of formula (I) having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: December 7, 2010
    Assignee: Glaxo Group Limited
    Inventors: Gordon Bruton, Anthony Huxley, Barry Sidney Orlek, Kishore Kalidas Rana
  • 1-Benzoyl Substituted Diazepine Derivatives As Selective Histamine H3 Receptor Agonists
    Publication number: 20080045505
    Abstract: The present invention relates to novel diazepanyl derivatives of formula (I) having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: October 14, 2004
    Publication date: February 21, 2008
    Inventors: Gordon Bruton, Anthony Huxley, Barry Sidney Orlek, Kishore Kalidas Rana
  • Substituted piperidines as histamine h3 receptor ligands
    Publication number: 20060247227
    Abstract: The present invention relates to novel piperidine ether derivatives having affinity for the histamine H3 receptor processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
    Type: Application
    Filed: July 16, 2004
    Publication date: November 2, 2006
    Inventors: James Bailey, Gordon Bruton, Anthony Huxley, Peter Milner, Barry Orlek