Abstract: There is described a self-sealing injection button adapted to be punctured by a hypodermic needle and a method for making such device. The button is preferably a unitary composite comprising at least one sheet of cloth or metal fabric impregnated with cured silicone rubber which has been swollen by absorption of a nonvolatile swelling agent such as dimethylpolysiloxane fluid. An alternate embodiment restrains the rubber in a rigid ring shaped retainer. The preferred method of making the device comprises interleaving the fabric sheets with uncured silicone rubber sheets, compressing the composite to embed the fabric in the uncured rubber, curing the rubber, and then immersing the cured composite in the swelling agent.