Patents by Inventor Anthony J. Capobianco

Anthony J. Capobianco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of the notch transcriptional activation complex kinase (“NACK”) and methods for use of the same
    Patent number: 11649214
    Abstract: Disclosed herein are Notch transcriptional activation complex kinase (“NACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (la) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: May 16, 2023
    Assignee: UNIVERSITY OF MIAMI
    Inventors: Anthony J. Capobianco, Stephan C. Schürer, Xiaoxia Zhu, Tanya T. Kelley
  • INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX KINASE ("NACK") AND METHODS FOR USE OF THE SAME
    Publication number: 20230113546
    Abstract: Disclosed herein are Notch transcriptional activation complex kinase (“MACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (Ia) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.
    Type: Application
    Filed: September 6, 2022
    Publication date: April 13, 2023
    Inventors: Anthony J. Capobianco, Stephan C Schúrer, Xiaoxia Zhu, Tanya T.. Kelley
  • IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME
    Publication number: 20220194932
    Abstract: Disclosed herein are inhibitors of the Notch transcriptional activation complex, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: Formula (I), wherein the substituents are as described.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 23, 2022
    Inventors: Anthony J. Capobianco, Mark Spyvee, Luisana Astudillo, Darren Orton
  • INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX KINASE ("NACK") AND METHODS FOR USE OF THE SAME
    Publication number: 20210171469
    Abstract: Disclosed herein are Notch transcriptional activation complex kinase (“NACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (la) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.
    Type: Application
    Filed: February 6, 2019
    Publication date: June 10, 2021
    Inventors: Anthony J. Capobianco, Stephan C. Schürer, Xiaoxia Zhu, Tanya T. Kelley
  • Inhibitors of the Notch transcriptional activation complex and methods for use of the same
    Patent number: 10501413
    Abstract: Disclosed herein are inhibitors of the Notch transcriptional activation complex, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: Formula (I), wherein the substituents are as described.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: December 10, 2019
    Assignees: UNIVERSITY OF MIAMI, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Anthony J. Capobianco, Alex Mackerell, Jr., Mark Spyvee
  • INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME
    Publication number: 20180086700
    Abstract: Disclosed herein are inhibitors of the Notch transcriptional activation complex, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: Formula (I), wherein the substituents are as described.
    Type: Application
    Filed: March 23, 2016
    Publication date: March 29, 2018
    Inventors: Anthony J. Capobianco, Alex Mackerell, JR., Mark Spyvee