Patents by Inventor Anthony J. Coyle

Anthony J. Coyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • B7-H2 molecules, novel members of the B7 family and uses thereof
    Publication number: 20090269783
    Abstract: Novel B7-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins, antigenic peptides, and anti-B7-like antibodies. The invention also provides B7-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: August 20, 2008
    Publication date: October 29, 2009
    Inventors: Anthony J. Coyle, Christopher C. Fraser, Stephen Manning
  • Screening methods using B7-H2 molecules, members of the B7 family
    Patent number: 7432062
    Abstract: Novel B7-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins, antigenic peptides, and anti-B7-like antibodies. The invention also provides B7-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: October 7, 2008
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Anthony J. Coyle, Christopher C. Fraser, Stephen Manning
  • B7-H2 molecules, novel members of the B7 family and uses thereof
    Publication number: 20040137577
    Abstract: Novel B7-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins, antigenic peptides, and anti-B7-like antibodies. The invention also provides B7-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: August 20, 2003
    Publication date: July 15, 2004
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Anthony J. Coyle, Christopher C. Fraser, Stephen Manning
  • B7-H2 nucleic acids, members of the B7 family
    Patent number: 6635750
    Abstract: B7-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins, antigenic peptides, and anti-B7-like antibodies. The invention also provides B7-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: October 21, 2003
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Anthony J. Coyle, Christopher C. Fraser, Stephen Manning
  • B7-H2 Polypeptides
    Patent number: 6630575
    Abstract: B7-Like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins, antigenic peptides, and anti-B7-like antibodies. The invention also provides B7-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: October 7, 2003
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Anthony J. Coyle, Christopher C. Fraser, Stephen Manning
  • Novel Th2-specific molecules and uses thereof
    Publication number: 20020164697
    Abstract: Novel Th2-specific polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length Th2-specific proteins, the invention further provides isolated Th2-specific fusion proteins, antigenic peptides, and anti-Th2-specific antibodies. The invention also provides Th2-specific nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a Th2-specific gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: November 20, 2001
    Publication date: November 7, 2002
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Anthony J. Coyle, Stephen Manning, Sophie Lehar, Jose-Carlos Gutierrez-Ramos
  • B7-H2 molecules, novel members of the B7 family and uses thereof
    Publication number: 20020106730
    Abstract: Novel B7-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins, antigenic peptides, and anti-B7-like antibodies. The invention also provides B7-like nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a B7-like gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: July 20, 2001
    Publication date: August 8, 2002
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Anthony J. Coyle, Christopher C. Fraser, Stephen Manning