Patents by Inventor Anthony J. DeGraffenreid

Anthony J. DeGraffenreid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Arsenic complexes for potential diagnostic applications
    Patent number: 9593052
    Abstract: The present invention provides radioactive arsenic complexes useful in diagnostic and therapeutic applications and methods for forming those arsenic complexes.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: March 14, 2017
    Assignee: The Curators of the University of Missouri
    Inventors: Silvia S. Jurisson, Cathy S. Cutler, Donald E. Wycoff, Anthony J. DeGraffenreid
  • Radioisotope trithiol complexes
    Patent number: 9427483
    Abstract: The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of radioisotopes present in low concentrations. In certain embodiments, the complex contains a linking domain configured to conjugate the radioisotope trithiol complex to a targeting vector. The invention is also directed to a novel method of linking the radioisotope to a trithiol compound to form the radioisotope trithiol complex. The inventive radioisotope trithiol complexes may be utilized for a variety of applications, including diagnostics and/or treatment in nuclear medicine.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: August 30, 2016
    Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: Silvia S. Jurisson, Cathy S. Cutler, Anthony J. Degraffenreid
  • ARSENIC COMPLEXES FOR POTENTIAL DIAGNOSTIC APPLICATIONS
    Publication number: 20160083408
    Abstract: The present invention provides radioactive arsenic complexes useful in diagnostic and therapeutic applications and methods for forming those arsenic complexes.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 24, 2016
    Applicant: The Curators of the University of Missouri
    Inventors: Silvia S. Jurisson, Cathy S. Cutler, Donald E. Wycoff, Anthony J. DeGraffenreid
  • RADIOISOTOPE TRITHIOL COMPLEXES
    Publication number: 20150283274
    Abstract: The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of radioisotopes present in low concentrations. In certain embodiments, the complex contains a linking domain configured to conjugate the radioisotope trithiol complex to a targeting vector. The invention is also directed to a novel method of linking the radioisotope to a trithiol compound to form the radioisotope trithiol complex. The inventive radioisotope trithiol complexes may be utilized for a variety of applications, including diagnostics and/or treatment in nuclear medicine.
    Type: Application
    Filed: April 6, 2015
    Publication date: October 8, 2015
    Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: SILVIA S. JURISSON, Cathy S. Cutler, Anthony J. Degraffenreid
  • ARSENIC COMPLEXES FOR POTENTIAL DIAGNOSTIC APPLICATIONS
    Publication number: 20140051840
    Abstract: The present invention provides radioactive arsenic complex useful in diagnostic and therapeutic applications and methods for forming those arsenic complexes.
    Type: Application
    Filed: August 16, 2013
    Publication date: February 20, 2014
    Inventors: Silvia S. Jurisson, Cathy S. Cutler, Donald E. Wycoff, Anthony J. DeGraffenreid