Patents by Inventor Anthony J. Martinez

Anthony J. Martinez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10328012
    Abstract: Provided are methods of treating skin with at least two alternating treatment modalities to improve the health and/or diminish signs of aging. Some methods according to the present invention may comprise topically applying at least two separate compositions, in a sequential, rotating, or alternating fashion to overcome adaptation, tolerance, or sensitization phenomena.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 25, 2019
    Assignee: Avon Products, Inc.
    Inventors: Simon Dutton, Daniel Thorn Leeson, Jeanine Schoen, Dana Von Bargen, Uma Santhanam, Jolanta Idkowiak-Baldys, Anthony David Gonzalez, Pradeep H. Yadav, Olga Maria Martinez-Avila, Lauren Policelli, Glen Thomas Anderson, Russell J. Wyborski
  • Publication number: 20180211317
    Abstract: The methods and systems described herein can be used for proactively monitoring regulatory compliance within an order management system, and for providing a real-time or near real-time recommendation relating to a subgroup of information containing suspicious attributes of a trade before the trade is executed. As such, market abuse monitoring is integrated with the order management system to provide historical trade data, identify a subgroup of information containing the suspicious attributes, and provide an actionable and contextualized real-time or near real-time recommendation to a compliance officer or other appropriate individual, officer, or office. As such, potential market abuse can be prevented by, for example, a rejection of the trade. By providing proactive surveillance rather than reactive surveillance relating to potential market abuse, fines or other consequences are also prevented. As such, compliance is improved.
    Type: Application
    Filed: January 25, 2018
    Publication date: July 26, 2018
    Applicant: FIDESSA PLC
    Inventors: Freddie Chiong, Kurt Erich Huhner, Adam Levy, Anthony J. Martinez, James J. Biancamano, Juan Carlos Mauras
  • Patent number: 7989554
    Abstract: A new method of preparing a tertiary alkyl ester of a polyalkylene oxide is provided. The new method employs milder conditions that avoid the back reaction to the starting polyalkylene oxide. The tertiary alkyl ester of a polyalkylene oxide is then reacted with a suitable acid to produce a polyalkylene oxide acid.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: August 2, 2011
    Assignee: Enzon Pharmaceuticals, Inc.
    Inventors: Hong Zhao, Anthony J. Martinez
  • Publication number: 20040053976
    Abstract: The present invention is directed to polymeric-prodrug transport forms of the formula: 1
    Type: Application
    Filed: August 8, 2003
    Publication date: March 18, 2004
    Inventors: Anthony J. Martinez, Annapurna Pendri, Richard B. Greenwald, Yun H. Choe
  • Patent number: 6638499
    Abstract: The present invention is directed to polymeric-prodrug transport forms of the formula: wherein: E1-4 are independently selected from the group consisting of hydrogen, C1-6 alkyls, C3-12 branched alkyls, C3-8 cycloalkyls, C1-6 substituted alkyls, C3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C1-6 heteroalkyls, substituted C1-6 heteroalkyls, C1-6 alkoxy, phenoxy, C1-6 heteroalkoxy, and at least one of E1-4 includes a B moiety, wherein B is a leaving group, OH, a residue of a hydroxyl-or amino-containing moiety or wherein J1 is the same as J, or another member of the group defining J and E5 is the same as E1-4, or another member of the group defining E1-4, Y1-2 are independently O, S or NR9; M is a heteroatom selected from either X or Q; wherein X is an electron withdrawing group and Q is a moiety containing a free electron pair positioned three to six atoms from C(═Y2); R2-5 and R7-9 are independently selected fro
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: October 28, 2003
    Assignee: Enzon, Inc.
    Inventors: Anthony J. Martinez, Annapurna Pendri, Richard B. Greenwald, Yun H. Choe
  • Patent number: 6566506
    Abstract: Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: May 20, 2003
    Assignee: Enzon, Inc.
    Inventors: Richard B. Greenwald, Anthony J. Martinez
  • Publication number: 20020103259
    Abstract: The present invention is directed to polymeric-prodrug transport forms of the formula: 1 2
    Type: Application
    Filed: February 6, 2002
    Publication date: August 1, 2002
    Inventors: Anthony J. Martinez, Annapurna Pendri, Richard B. Greenwald, Yun H. Choe
  • Patent number: 6395266
    Abstract: The present invention is directed to polymeric-prodrug transport forms of the formula: wherein: E1-4 are independently selected from the group consisting of hydrogen, C1-6 alkyls, C3-12 branched alkyls, C3-8 cycloalkyls, C1-6 substituted alkyls, C3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C1-6 heteroalkyls, substituted C1-6 heteroalkyls, C1-6 alkoxy, phenoxy, C1-6 heteroalkoxy, and at least one of E1-4 includes a B moiety, wherein B is a leaving group, OH, a residue of a hydroxyl-or amino-containing moiety or wherein J1 is the same as J, or another member of the group defining J and E5 is the same as E1-4, or another member of the group defining E1-4; Y1-2 are independently O, S or NR9; M is a heteroatom selected from either X or Q; wherein X is an electron withdrawing group and Q is a moiety containing a free electron pair positioned three to six atoms from C(=Y2); R2-5 and R7-9 are independently selected
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: May 28, 2002
    Assignee: Enzon, Inc.
    Inventors: Anthony J. Martinez, Annapurna Pendri, Richard B. Greenwald, Yun H. Choe
  • Publication number: 20020052443
    Abstract: Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.
    Type: Application
    Filed: April 7, 2000
    Publication date: May 2, 2002
    Inventors: Richard B Greenwald, Anthony J Martinez
  • Patent number: 6251382
    Abstract: Polymeric compounds of the formula: (D)n—M—(R1)m  (I) wherein (m) and (n) independently selected positive integers, preferably from about 1 to about 6 each; D is a residue of a biologically active moiety; M is a multifunctional linker/spacer moiety; and R1 is a polymer residue are disclosed. Methods of preparing the same and methods of treatment using the same are also included as part of the present invention.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: June 26, 2001
    Assignee: Enzon, Inc.
    Inventors: Richard B. Greenwald, Anthony J. Martinez, Yun H. Choe, Annapurna Pendri
  • Patent number: 6153655
    Abstract: The present invention is directed to polymeric- prodrug transport forms of the formula: ##STR1## wherein: B is a leaving group, OH, a residue of a hydroxyl-containing moiety or ##STR2## wherein B.sub.1 is a leaving group, OH or a residue of a hydroxyl-containing moiety;Y.sub.1-2 are independently O or S;M is selected from either X or Q; wherein X is an electron withdrawing group and Q is a moiety containing a free electron pair positioned three to six atoms from C(.dbd.Y.sub.2); R.sub.2-5 are independently selected from the group consisting of hydrogen, C.sub.1-6 alkyls, C.sub.3-12 branched alkyls, C.sub.3-8 cycloalkyls, C.sub.1-6 substituted alkyls, C.sub.3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C.sub.1-6 heteroalkyls and substituted C.sub.1-6 heteroalkyls;(m) is zero or one;(n) is a positive integer;(p) is zero or a positive integer;Z is an electron withdrawing group; andR.sub.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: November 28, 2000
    Assignee: Enzon, Inc.
    Inventors: Anthony J. Martinez, Annapurna Pendri, Richard B. Greenwald, Yun H. Choe
  • Patent number: 6113906
    Abstract: Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.
    Type: Grant
    Filed: December 29, 1998
    Date of Patent: September 5, 2000
    Assignee: Enzon, Inc.
    Inventors: Richard B. Greenwald, Anthony J. Martinez
  • Patent number: 5919455
    Abstract: Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: July 6, 1999
    Assignee: Enzon, Inc.
    Inventors: Richard B. Greenwald, Anthony J. Martinez
  • Patent number: 5756593
    Abstract: The present invention is directed to methods of preparing high purity polyalkylene oxide carboxylic acids. The methods include reacting a polyalkylene oxide such as polyethylene glycol with a t-butyl haloacetate in the presence of a base followed by treatment with an acid such as trifloroacetic acid. The resultant polymer carboxylic acids are of sufficient plurty so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: May 26, 1998
    Assignee: Enzon, Inc.
    Inventors: Anthony J. Martinez, Richard B. Greenwald
  • Patent number: 5681567
    Abstract: The present invention is directed to methods of preparing high purity polyalkylene oxide carboxylic acids. The methods include reacting a polyalkylene oxide such as polyethylene glycol with a t-butyl haloacetate in the presence of a base followed by treatment with an acid such as trifluoroacetic acid. The resultant polymer carboxylic acids are of sufficient purity so that expensive and time containing purification steps required for pharmaceutical grade polymers are avoided.
    Type: Grant
    Filed: August 13, 1996
    Date of Patent: October 28, 1997
    Assignee: Enzon, Inc.
    Inventors: Anthony J. Martinez, Richard B. Greenwald
  • Patent number: 5605976
    Abstract: The present invention is directed to methods of preparing high purity polyalkylene oxide carboxylic acids. The methods include reacting a polyalkylene oxide such as polyethylene glycol with a t-butyl haloacetate in the presence of a base followed by treatment with an acid such as trifluoroacetic acid. The resultant polymer carboxylic acids are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: February 25, 1997
    Assignee: Enzon, Inc.
    Inventors: Anthony J. Martinez, Richard B. Greenwald
  • Patent number: 5405877
    Abstract: Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.
    Type: Grant
    Filed: August 29, 1994
    Date of Patent: April 11, 1995
    Assignee: Enzon, Inc.
    Inventors: Richard B. Greenwald, Anthony J. Martinez
  • Patent number: 5349001
    Abstract: Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.
    Type: Grant
    Filed: January 19, 1993
    Date of Patent: September 20, 1994
    Assignee: Enzon, Inc.
    Inventors: Richard B. Greenwald, Anthony J. Martinez
  • Patent number: 5081287
    Abstract: The present invention discloses and exemplifies alcohol, ether and ester derivatives of difluoroalkanes and difluoroalkenylalkanes having the general formula R--(CH.sub.2).sub.m --CR.sup.2 R.sup.3 --OR.sup.1, in which R is a 1,1-difluoroalkyl or a 1,1-difluoroalkenyl group, composition thereof, and use thereof to control agricultural crop pests.
    Type: Grant
    Filed: June 30, 1989
    Date of Patent: January 14, 1992
    Assignee: FMC Corporation
    Inventors: Clinton J. Peake, Thomas G. Cullen, Anthony J. Martinez
  • Patent number: 4952580
    Abstract: Polyhaloalkene compounds of the formula: ##STR1## wherein X is sulfur, oxygen, or nitrogen, Y.sup.1 and Y.sup.2 are fluorine, Z is hydrogen or the same as Y.sup.1 and Y.sup.2, and n is 1-4; provided that:(A) when X is sulfur, Z is fluorine and R is thienyl or substituted thienyl, thianaphthyl or substituted thianaphthyl, thiazolinyl or substituted thiazolinyl, oxadiazolyl or substituted oxadiazolyl, 3,4,4-trifluoro-3-butenyloxycarbonylmethyl, thiadiazolyl substituted by halogen or R.sup.2 S, wherein R.sup.2 is 3,4,4-trifluoro-3-butenyl or R.sup.2 is phenylmethyl or phenylthiomethyl each optionally substituted by halogen or nitro; or R is thiadiazolyl substituted by R.sup.3, wherein R.sup.3 is substituted aryl, arylalkyl, aryloxyalkyl, alkylthio, haloalkylthio, haloarylthio, cyanoalkylthio, arylalkylthio, aryloxyalkylthio, arylthioalkylthio, heterocycloalkylthio, alkenylthio, haloalkenylthio, halocycloalkylalkenylthio, wherein said aryl or heterocyclic groups of R.sup.
    Type: Grant
    Filed: November 9, 1988
    Date of Patent: August 28, 1990
    Assignee: FMC Corporation
    Inventors: Anthony J. Martinez, Thomas G. Cullen