Abstract: A connection system for providing a consumer-friendly connection between an expansion card and a host device. The host device includes a male connection while the expansion card includes a female connection. The male and female connections are arranged in a pattern that allows a combination of keyed voltage connections between the host device and expansion card when the supply voltage of the host and operating voltage of the card are compatible. The male connection includes six different supply voltage combinations that include a first voltage only, a second voltage only, a third voltage only, a first and second voltage only, a second and third voltage only, and a first, second and third voltage combination. In addition, the female connection includes six different expansion card operating voltage combinations that include a first voltage only, a second voltage only, a third voltage only, a first and second voltage only, a second and third voltage only, and a first, second and third voltage combination.