Abstract: The present disclosure relates to a system (10) for measuring the mechanical properties of a skin sample (3) ex vivo or in vitro, comprising a measuring device comprising at least one mechanical stress module (20, 40) capable of applying a tensile force to the skin in a direction parallel to the surface of the skin sample (3), the at least one mechanical stress module (20, 40) comprising: —a traction means (30, 50) which is translatably movable in a direction parallel to the surface of the skin sample (3); — a translating arm (21, 41) connected, on the one hand, to the traction means (30, 50) and, on the other hand, to an axial displacement means; — one end of the traction means being provided with an attachment head (31, 51) capable of being attached to a region of the skin sample (3) so as to cause deformation of the skin sample by axially displacing the region of the skin sample— a control unit (202) configured to control the displacement means according to a stress frequency of between 0.