Patents by Inventor Anthony Marrotta

Anthony Marrotta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 14-3-3 ETA Antibodies and Uses Thereof for the Diagnosis and Treatment of Arthritis
    Publication number: 20110052573
    Abstract: The invention provides anti-14-3-3 eta antibodies that specifically bind to the human 14-3-3 eta protein isoform in its natural configuration while exhibiting selectivity over human 14-3-3 alpha, beta, delta, epsilon, gamma, tau, and zeta protein isoforms. Methods, kits and pharmaceutical compositions comprising said specific anti-14-3-3 eta antibodies are further provided for the diagnosis and treatment of arthritis.
    Type: Application
    Filed: November 26, 2008
    Publication date: March 3, 2011
    Applicant: The University of British Columbia
    Inventor: Anthony Marrotta
  • 14-3-3 Antagonists for the Prevention and Treatment of Arthritis
    Publication number: 20110027269
    Abstract: Methods for treating arthritis comprising 14-3-3 antagonists that are capable of specifically binding to extracellularly localized 14-3-3 eta and/or 14-3-3 gamma protein isoforms are provided. In preferred embodiments, the 14-3-3 antagonist is an inhibitory peptide or an anti-14-3-3 antibody. The 14-3-3 antagonists are also formulated in a pharmaceutical composition and used in a method for reducing matrix metalloprotease (MMP) expression in the synovial fluid of a patient, wherein the MMP is MMP-1 or MMP-3.
    Type: Application
    Filed: November 26, 2008
    Publication date: February 3, 2011
    Inventors: Anthony Marrotta, Aziz Ghahary, Walter Wolodmyr Peter Maksy mowych, Ruhangiz Kilani