Patents by Inventor Anthony Monaco

Anthony Monaco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Probes for and nucleic acid encoding the muscular dystrophy protein, dystrophin
    Patent number: 5621091
    Abstract: The invention relates to a muscular dystrophy (MD) probe comprising a substantially purified single-stranded nucleic acid sequence capable of hybridizing to a region of DNA on a human X chromosome between the deletion break point at Xp21.3 and the translocation break point at X;11. The invention also relates to a 14 kb cDNA corresponding to the complete MD gene and probes produced therefrom useful in genetic methods of diagnosis of MD. Furthermore, the invention relates to the polypeptide, dystrophin, which corresponds to the MD gene product, and antibodies thereto that are useful in a variety of methods for immunodiagnosis of MD.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: April 15, 1997
    Assignee: The Children's Medical Center Corporation
    Inventors: Louis M. Kunkel, Anthony Monaco, Eric P. Hoffman, Michel Koenig
  • Antibodies to dystrophin and uses therefor
    Patent number: 5541074
    Abstract: The invention relates to a muscular dystrophy (MD) probe comprising a substantially purified single-stranded nucleic acid sequence capable of hybridizing to a region of DNA on a human X chromosome between the deletion break point at Xp21.3 and the translocation break point at X;11. The invention also relates to a 14 kb cDNA corresponding to the complete MD gene and probes produced therefrom useful in genetic methods of diagnosis of MD. Furthermore, the invention relates to the polypeptide, dystrophin, which corresponds to the MD gene product, and antibodies thereto that are useful in a variety of methods for immunodiagnosis of MD.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: July 30, 1996
    Assignee: The Children's Medical Center Corporation
    Inventors: Louis M. Kunkel, Anthony Monaco, Eric P. Hoffman, Michel Koenig
  • Muscular dystrophy protein, dystrophin
    Patent number: 5239060
    Abstract: The invention relates to a muscular dystrophy (MD) probe comprising a substantially purified single-stranded nucleic acid sequence capable of hybridizing to a region of DNA on a human X chromosome between the deletion break point at Xp21.3 and the translocation break point at X;11. The invention also relates to a 14 kb cDNA corresponding to the complete MD gene and probes produced therefrom useful in genetic methods of diagnosis of MD. Furthermore, the invention relates to the polypeptide, dystrophin, which corresponds to the MD gene product, and antibodies thereto that are useful in a variety of methods for immunodiagnosis of MD.
    Type: Grant
    Filed: December 22, 1987
    Date of Patent: August 24, 1993
    Assignee: The Children's Medical Center Corporation
    Inventors: Louis M. Kunkel, Anthony Monaco, Eric P. Hoffman, Michel Koenig
  • Labor saving lawn implement
    Patent number: 4888942
    Abstract: A yard implement is provided for working piles of fallen leaves. The implement is a device for pushing leaves under conditions which normally would require raking and/or blowing. A pusher blade is attached to a handle, and the blade is configured to maximize the mass of leaves that can be moved and to minimize the pushing effort required to move a given mass of leaves.
    Type: Grant
    Filed: May 18, 1988
    Date of Patent: December 26, 1989
    Inventor: Anthony Monaco