Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.

Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.

Abstract: A motorized personal skin care implement capable of use with a disposable, single-use, skin care pad is disclosed with a molded hook arrangement for releasably but firmly holding the pad while cleansing or treating the skin but allowing for quick removal and replacement with a fresh cleansing or treatment pad. A method of using the skin care implement and a kit containing at least one pad and the implement is also described.

Abstract: A colored article suitable for cleansing skin having the general form of a fibrous bar is described. The article includes a solid or semi-solid lathering composition that at least partially incorporates a continuous fabricated polymeric network. The articles have a substantially red color defined by L*,a*,b* chromaticity values falling within a specific region of the CIE color space and exhibit a low tendency for discoloration in storage and use.

Abstract: A process and equipment for manufacture of a swab article is provided wherein a stick is placed onto a conveyor, adhesive is applied to one or both ends of the stick, a portion of cotton coil is attached to the adhesive bearing end, and a shaper bar or similar means forces the cotton to assume a teardrop profile by applying force parallel to the stick, wherein the shaper bar or similar means moves in a direction perpendicular to the stick at a different rate of speed than that of the stick. Differences in the rate of speed reduce tailing of cotton normally associated with drag.

Abstract: Agents and methods for qualitative and quantitative analysis a protein complex or protein complexes using isotope-labeled symmetrical bifunctional crosslinkers and mass spectrometry are provided. Targeting moieties, cell permeability moieties, or affinity moieties, may be appended to the bifunctional crosslinkers. The isotope-labeled symmetrical bifunctional crosslinkers may be used in a kit or as a library.

Abstract: A combined toroid/shunt device for detecting residual current in an electrical installation comprising a plurality of conductors such as a live conductor (2) and a neutral conductor (3) is described. The device comprises a toroid means (1, 4) for detecting an AC residual current within a first range and a plurality of resistive shunts (6a) to (6d) for connection in respective ones of the plurality of conductors. A current detection means (5, 7, 13) responsive to current flowing in each of said shunts for detecting a DC residual current and/or an AC residual current within a second range is described. The first range of AC residual current is an AC residual current resulting from earth leakage or cross-leakage between conductors up to a saturation level at which the toroid or electronic means associated means therewith becomes saturated. The second range includes an AC residual current of said saturation level.

Abstract: This invention relates to compounds of formula (I) which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.

Abstract: This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. The compounds are of the general formula (I) wherin A and B are further defined in the application.

Abstract: A method and an apparatus raise samples of liquid such as water from a low level to a higher level, for example for obtaining a sample of groundwater from a borehole. The apparatus comprises a pair of tubes (14 and 16) extending alongside each other, which are introduced into the borehole, linked by a connector (20) at their lower end, a valve (22) communicating between the inside and outside of one of the tubes (16) near its lower end, and a pig (46) insertable into the tube (16). By adjusting the pressure in each tube at their upper end, the pig (46) can be moved from one end to the other of the apparatus (10) and used to transfer samples of water.

Abstract: This invention relates to aryl carbonyl derivativeswhich are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.

Abstract: Disclosed are novel compounds of formula (I) wherein A1, A2, Ar, R5, R6, R8, M, Q, Y, Z, k, m and n are as defined in the specification. These compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR). Such conditions include diabetes and obesity.

Abstract: A cosmetic product system is provided which includes a cosmetic composition for combating signs of aging, and a test device packaged with the composition. The device includes a mechanism for evaluating progress of the combat against the signs of aging occurring over a period of time within which the composition is applied to an area of skin being monitored.

Abstract: A process and equipment for manufacture of a swab article is provided wherein a stick is placed onto a conveyor, adhesive is applied to one or both ends of the stick, a portion of cotton coil is attached to the adhesive bearing end, and a shaper bar or similar means forces the cotton to assume a teardrop profile by applying force parallel to the stick, wherein the shaper bar or similar means moves in a direction perpendicular to the stick at a different rate of speed than that of the stick. Differences in the rate of speed reduce tailing of cotton normally associated with drag.

Abstract: Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.

Abstract: Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.

Abstract: A test kit and method for visualizing fine lines and wrinkles is provided, the kit including a transparent strip with an adhesive on one surface thereof and an imaging substrate with at least one darkened glossy area for receiving the transparent strip. Written instructions are provided in the kit. These advise a consumer to place the adhesive surface of the strip against a skin area requiring measurement. Thereafter the strip is removed and placed against the darkened area of the substrate. Topographical features of the skin can be viewed through the transparent strip with the transferred skin image onto the blackened background. A cosmetic anti-aging product can be applied to the skin over a period of time. Beneficial changes caused by the product are visualized through the test strip as periodic measurements are taken.

Abstract: Certain compounds, structurally related to natural compounds which can be extracted i.a. from bull testes and from human follicular fluid, can be used for regulating the meiosis in oocytes and in male germ cells. Some of these compounds are useful in the treatment of infertility, whereas other compounds are useful as contraceptives. These compounds have the structural formula wherein the substituents are as defined in the specification.

Abstract: A process and equipment for manufacture of a swab article is provided wherein a stick is placed onto a conveyor, adhesive is applied to one or both ends of the stick, a portion of cotton coil is attached to the adhesive bearing end, and a shaper bar or similar means forces the cotton to assume a teardrop profile by applying force parallel to the stick, wherein the shaper bar or similar means moves in a direction perpendicular to the stick at a different rate of speed than that of the stick. Differences in the rate of speed reduce tailing of cotton normally associated with drag.

Abstract: Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.