Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.

Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.

Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.

Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.

Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tan protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Abstract: The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.

Abstract: The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Abstract: An implantable medical device includes a bioerodible portion adapted to erode when exposed to a physiological environment. The bioerodible portion includes an alloy comprising at least 10 weight percent chromium and has an outer surface having a ratio of chromium oxide to chromium metal of less than 5. The bioerodible implantable medical device can be created by implanting metallic ions into an alloy including at least 10 weight percent chromium to define an outer surface of a medical implant, or precursor thereof.

Abstract: A plastic lawn-edging strip (1) for separating different areas of lawns and gardens comprises an elongate strip of plastic material formed from a) a first elongate portion (2), comprising bottom edge (5), inner and outer faces (6), adapted to allow forced insertion thereof into the ground between a lawn and a garden and to form a wall to the lawn edge; and, connected to the first portion, b) a second elongate portion (3), comprising top edge (7), inner and outer faces (8, 9), and a plurality of apertures (10) adapted such that in use said apertures receive grass and grass roots that anchor said second elongate portion to the lawn.

Abstract: A diary product contains dairy proteins, the product being at least semi-solid and containing greater than 0.15% by weight of casein macropeptide (CMP). The mass ratio of CMP to whey protein is 1:4.9 or greater. The product may be a natural cheese or a processed cheese. To obtain the desired product, a natural casein isolate protein (NCI) source is combined with a moisture and a fat source and coagulated.

Abstract: A diary product contains dairy proteins, the product being at least semi-solid and containing greater than 0.15% by weight of casein macropeptide (CMP). The mass ratio of CMP to whey protein is 1:4.9 or greater. The product may be a natural cheese or a processed cheese. To obtain the desired product, a natural casein isolate protein (NCI) source is combined with a moisture and a fat source and coagulated.

Abstract: The present invention provides a generic interface which enables asynchronous data processing elements to be interconnected using an interconnection protocol that controls flow of data between the processing elements. The flow control allows the processing elements to be data independent from, i.e., the processing elements need not be designed for a fixed sample rate or resolution, sample format and other data dependent factors. When used with digital motion video data, the processing elements may process motion video data at various temporal and spatial resolutions and color formats. Flow of data between processing elements may be controlled by handshake signals indicating whether the sender has valid data and the receiver can receive data. When valid data is available at the sender and is requested by the receiver, a transfer of data occurs. The characteristics of the data, and functions to be performed on the data may be specified using control inputs to the processing elements.