Patents by Inventor Anthony Oro

Anthony Oro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of atypical protein kinase C and their use in treating hedgehog pathway-dependent cancers
    Patent number: 9597369
    Abstract: Methods and compositions are provided for modulating Hedgehog (Hh) pathway signaling in a cell. Aspects of the methods include methods for inhibiting Hh pathway-promoted cancer proliferation and/or metastasis that is promoted by Hh pathway signaling, methods for treating cancers promoted by Hh pathway signaling, and methods for screening candidate agents for the ability to treat a cancer promoted by Hh pathway signaling. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: March 21, 2017
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Scott X. Atwood, Anthony Oro
  • Compositions for increasing hair growth
    Patent number: 9333209
    Abstract: Cosmetic skin and hair care compositions for enhancing the growth and appearance of mammalian hair in an individual are provided, which compositions comprise a dose of an L-type calcium channel blocker effective to promote anagen phase of the hair cycle. As shown herein, anagen phase promotion can result in more rapid hair growth.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: May 10, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Anthony Oro, Ricardo Ei Dolmetsch, Gozde Yucel
  • Inhibitors of Atypical Protein Kinase C and Their Use in Treating Hedgehog Pathway-Dependent Cancers
    Publication number: 20150335702
    Abstract: Methods and compositions are provided for modulating Hedgehog (Hh) pathway signaling in a cell. Aspects of the methods include methods for inhibiting Hh pathway-promoted cancer proliferation and/or metastasis that is promoted by Hh pathway signaling, methods for treating cancers promoted by Hh pathway signaling, and methods for screening candidate agents for the ability to treat a cancer promoted by Hh pathway signaling. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.
    Type: Application
    Filed: June 2, 2015
    Publication date: November 26, 2015
    Inventors: Scott X. Atwood, Anthony Oro
  • Inhibitors of atypical protein kinase C and their use in treating hedgehog pathway-dependent cancers
    Patent number: 9073964
    Abstract: Methods and compositions are provided for modulating Hedgehog (Hh) pathway signaling in a cell. Aspects of the methods include methods for inhibiting Hh pathway-promoted cancer proliferation and/or metastasis that is promoted by Hh pathway signaling, methods for treating cancers promoted by Hh pathway signaling, and methods for screening candidate agents for the ability to treat a cancer promoted by Hh pathway signaling. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: July 7, 2015
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Scott X. Atwood, Anthony Oro
  • Compositions for Increasing Hair Growth
    Publication number: 20150005291
    Abstract: Cosmetic skin and hair care compositions for enhancing the growth and appearance of mammalian hair in an individual are provided, which compositions comprise a dose of an L-type calcium channel blocker effective to promote anagen phase of the hair cycle. As shown herein, anagen phase promotion can result in more rapid hair growth.
    Type: Application
    Filed: February 8, 2013
    Publication date: January 1, 2015
    Inventors: Anthony Oro, Ricardo Ei Dolmetsch, Gozde Yucel
  • Bone morphogenetic protein antagonist and uses thereof
    Patent number: 8383349
    Abstract: The present invention relates to the use of proteins that are differentially expressed in tumor associated stromal cells, as compared to normal stromal, as biomolecular targets for tumor treatment therapies. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: February 26, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Hanson Zhen, Julie Sneddon, Patrick O. Brown, Anthony Oro
  • Inhibitors of Atypical Protein Kinase C and Their Use in Treating Hedgehog Pathway-Dependent Cancers
    Publication number: 20120283194
    Abstract: Methods and compositions are provided for modulating Hedgehog (Hh) pathway signaling in a cell. Aspects of the methods include methods for inhibiting Hh pathway-promoted cancer proliferation and/or metastasis that is promoted by Hh pathway signaling, methods for treating cancers promoted by Hh pathway signaling, and methods for screening candidate agents for the ability to treat a cancer promoted by Hh pathway signaling. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.
    Type: Application
    Filed: March 16, 2012
    Publication date: November 8, 2012
    Inventors: Scott X. Atwood, Anthony Oro
  • Bone morphogenetic protein antagonist and uses thereof
    Publication number: 20090041757
    Abstract: The present invention relates to the use of proteins that are differentially expressed in tumor associated stromal cells, as compared to normal stromal, as biomolecular targets for tumor treatment therapies. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention.
    Type: Application
    Filed: March 13, 2008
    Publication date: February 12, 2009
    Inventors: Hanson Zhen, Julie Sneddon, Patrick O. Brown, Anthony Oro