Abstract: The present disclosure relates to improved magnetic mixing assemblies and mixing system. The magnetic mixing assemblies can provide improved mixing action, ease of use, and low friction. The mixing assemblies can be adapted for use with a wide variety of containers including narrower neck containers and flexible containers.

Abstract: A configurable port fitting for a container, such as a bioprocess bag, has one or more O-ring grooves and two opposing locking arms (e.g., 604). The port fitting is mounted onto the container by (i) inserting one end of the port fitting into a port in the container such that O-ring(s) form seals between the O-ring grooves and the container and (ii) rotating the port fitting to engage the locking arms with two opposing retention clips (e.g., 506) of the container. Some port fittings are fixed port fittings that provide a fixed opening into the container. Other port fittings are port sizers that receive a valve connector that enables flow control between closed and open positions. Port fittings of different sizes enable different flow rates. Some port fittings (and other connectors) have a threaded tube barb that receives a threaded tube retainer that secures tubing in place over the barb.

Abstract: Systems and methods are disclosed that include an operation chamber, a plasma generator having at least one plasma head disposed within the operation chamber and in proximity to a profile formed by cutting a piece of tubing, and a mechanical motion module. The plasma generator generates a plasma treatment and applies the plasma treatment via the at least one plasma head to the profile to activate material on an end surface of the profile, within a lumen of the profile, or a combination thereof. Once the material of the profile is activated by the plasma treatment, the mechanical motion module manipulates the profile to close the lumen of the profile to aseptically seal the profile.

Abstract: Systems and methods are disclosed that include generating a plasma treatment and applying the plasma treatment to end contact surfaces of a first profile and a second profile in a sterile environment, manipulating at least one of the first profile and the second profile to force contact between the end contact surface of the first profile and the end contact surface of the second profile to permanently connect, join, or weld the end contact surfaces of the first profile and the second profile together, thereby forming a sterile connection between the first profile and a second profile.

Abstract: Embodiments of the present disclosure are directed to an IR tube sealing device and method of sealing a polymer tube with infrared energy. In particular embodiments, the IR tube sealing device can be a portable, hand-held device adapted to receive and compress a polymer tube, and produce and direct infrared energy toward the compressed polymer tube to quickly form a permanent aseptic seal.

Abstract: The present disclosure relates to improved magnetic mixing assemblies and mixing system. The magnetic mixing assemblies can provide improved mixing action, ease of use, and low friction. The mixing assemblies can be adapted for use with a wide variety of containers including narrower neck containers and flexible containers.

Abstract: A pump comprising a housing defining an internal volume; an impeller disposed in the internal volume of the housing, wherein the impeller comprises a magnetic element and at least a portion of the surface of the impeller conforms to a generally logarithmic spiral; and a drive element adapted to magnetically couple with the magnetic element of the impeller.

Abstract: The present disclosure relates to improved magnetic mixing assemblies and mixing system. The magnetic mixing assemblies can provide improved mixing action, ease of use, and low friction. The mixing assemblies can be adapted for use with a wide variety of containers including narrower neck containers and flexible containers.

Abstract: The present disclosure relates to improved magnetic mixing assemblies and mixing system. The magnetic mixing assemblies can provide improved mixing action, ease of use, and low friction. The mixing assemblies can be adapted for use with a wide variety of containers including narrower neck containers and flexible containers.

Abstract: Embodiments of the present disclosure are directed to an IR tube sealing device and method of sealing a polymer tube with infrared energy. In particular embodiments, the IR tube sealing device can be a portable, hand-held device adapted to receive and compress a polymer tube, and produce and direct infrared energy toward the compressed polymer tube to quickly form a permanent aseptic seal.

Abstract: The present disclosure relates to improved magnetic mixing assemblies and mixing system. The magnetic mixing assemblies can provide improved mixing action, ease of use, and low friction. The mixing assemblies can be adapted for use with a wide variety of containers including narrower neck containers and flexible containers.

Abstract: The present disclosure relates to improved magnetic mixing assemblies and mixing system. The magnetic mixing assemblies can provide improved mixing action, ease of use, and low friction. The mixing assemblies can be adapted for use with a wide variety of containers including narrower neck containers and flexible containers.

Abstract: The disclosure is directed to a tube. The tube includes a silicone elastomer and at least one reinforcement member substantially embedded within the silicone elastomer. The disclosure is also directed to a tube including a first layer and a second layer adjacent the first layer. The first layer includes a fluoropolymer liner and the second layer includes a silicone elastomer and at least one reinforcement member substantially embedded within the silicone elastomer. This disclosure is further directed to a method for making the aforementioned tubes.