Abstract: Automated software code validation and deployment can include obtaining software code. The software code can be created via interactions with a computing device. In response to obtaining the software code and prior to receiving a request to deploy the software code, a security scan can be performed on the software code. After performing the security scan on the software code, a request to deploy the software code can be detected and in response to detecting the request, it can be determined if the software code includes a vulnerability that was detected during the security scan. If a determination is made that the software code does not include the vulnerability, the software code can be deployed. If a determination is made that the software code includes the vulnerability, deployment of the software code can be terminated, a security scan report can be generated, and the security scan report can be output.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Disclosed herein are methods for preparing tertiary alcohols from an optionally substituted phenyl ketone or an optionally substituted pyridinyl ketone that includes the use of a chiral ligand and boron trifluoride diethyl etherate. Tertiary alcohols can be used to prepare synthetic versions of natural products and/or pharmaceuticals.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: The present invention discloses cured composites having improved surfaces and processes of making and methods of using same. Such processes use ultra-short pulse lasers, for example, a femto-second laser to ablate material without the detrimental heat affected zones of other laser processes. Such process can not only increases surface roughness and clean contaminates, but can also selectively remove the matrix material and expose the surface fibers of cured composites. The treated cured composites have improved thermal and electrical pathways that can dissipate unwanted heat and electricity when two or more prepregs and/or cured composites are bonded or cured to form a single article.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their preparation.

Abstract: A method of tracking a plurality of signals from a single satellite comprises receiving a first signal transmitted by a satellite; receiving at least a second signal transmitted by the same satellite; applying a pre-filtering process to determine the cumulative in-phase and quadrature components of the first, second signals, and optionally any further signals; and applying a filtering process to the cumulated in-phase and quadrature components of the first and at least second signals to determine a range and range rate of the satellite; wherein the filtering process comprises applying a Kalman filter. The method results in a determination of the range and range rate from a single satellite with improved signal to noise ratio. The range and range rate so determined may be used, with data from other satellites, to produce a navigational position. The method may be used with each such satellite used in producing the navigational position.

Abstract: Described herein are methods of treating a metabolic disorder in an individual in need thereof, comprising co-administering to the individual a therapeutically effective amount of an FXR modulator, and at least one second agent that is an CCR2/CCR5 antagonist, ASK1 inhibitor, DPP-IV inhibitor, caspase protease inhibitor, SGLT2 inhibitor, acetyl-CoA carboxylase (ACC) inhibitor, diacylglycerol acyltransferase-1 inhibitor, sodium-bile acid cotransporter-inhibitor, TLR-4 antagonist, PPAR alpha/delta agonist, or GLP-1 agonist, or a combination thereof.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

Abstract: A method of tracking a plurality of signals from a single satellite comprises receiving a first signal transmitted by a satellite; receiving at least a second signal transmitted by the same satellite; applying a pre-filtering process to determine the cumulative in-phase and quadrature components of the first, second signals, and optionally any further signals; and applying a filtering process to the cumulated in-phase and quadrature components of the first and at least second signals to determine a range and range rate of the satellite; wherein the filtering process comprises applying a Kalman filter. The method results in a determination of the range and range rate from a single satellite with improved signal to noise ratio. The range and range rate so determined may be used, with data from other satellites, to produce a navigational position. The method may be used with each such satellite used in producing the navigational position.

Abstract: A compound having the Formula (I), or a pharmaceutically acceptable salt or solvate thereof: