Patents by Inventor Anthony Purchio

Anthony Purchio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing C3A serum-free clonal cell line
    Patent number: 8715954
    Abstract: A serum-free C3A clonal cell line and methods for generating the same are provided. The C3A cell line has a reduced doubling time in serum-free medium compared to a corresponding C3A cell line from which it is derived. Methods using the cells of the serum-free C3A clonal cell line for the production, expression and recovery of harvestable polypeptides, screening compounds for metabolic activity, studying enteric disease and for use in a bio-artificial liver device are also provided.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: May 6, 2014
    Assignee: Vital Therapies, Inc.
    Inventors: Dennis Triglia, Anthony Purchio
  • C3A Serum-Free Clonal Cell Line and Methods of Use
    Publication number: 20090035805
    Abstract: A serum-free C3A clonal cell line and methods for generating the same are provided. The C3A cell line has a reduced doubling time in serum-free medium compared to a corresponding C3A cell line from which it is derived. Methods using the cells of the serum-free C3A clonal cell line for the production, expression and recovery of harvestable polypeptides, screening compounds for metabolic activity, studying enteric disease and for use in a bio-artificial liver device are also provided.
    Type: Application
    Filed: June 20, 2008
    Publication date: February 5, 2009
    Inventors: Dennis Triglia, Anthony Purchio
  • Isolation and identification of mouse and human transcription control elements associated with cytochrome expression
    Patent number: 7449567
    Abstract: The present invention relates to transcription control elements derived from mouse and human genes associated with cytochrome expression, e.g., Cyp3A11 and CYP3A4, respectively. Isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, may comprise such transcription control elements as described herein.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: November 11, 2008
    Assignee: Xenogen Corporation
    Inventors: Weisheng Zhang, Pamela Contag, Anthony Purchio, Sandy Hashima, Shirley Ma, Kevin Nawotka
  • C3A serum-free clonal cell line and methods of use
    Patent number: 7390651
    Abstract: A serum-free C3A clonal cell line and methods for generating the same are provided. The C3A cell line has a reduced doubling time in serum-free medium compared to a corresponding C3A cell line from which it is derived. Methods using the cells of the serum-free C3A clonal cell line for the production, expression and recovery of harvestable polypeptides, screening compounds for metabolic activity, studying enteric disease and for use in a bio-artificial liver device are also provided.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: June 24, 2008
    Assignee: Vital Therapies, Inc.
    Inventors: Dennis Triglia, Anthony Purchio
  • Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
    Patent number: 7115793
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. Such transcription control elements may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, as described herein.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: October 3, 2006
    Assignee: Xenogen Corporation
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt
  • Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
    Publication number: 20050138678
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. Such transcription control elements may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, as described herein.
    Type: Application
    Filed: November 16, 2004
    Publication date: June 23, 2005
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt
  • Transgenic mice comprising transcription control elements associated with mouse eosinophil peroxidase expression
    Patent number: 6858773
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. The novel transcription control elements described in the disclosure may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: February 22, 2005
    Assignee: Xenogen Corporation
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt
  • C3A serum-free clonal cell line and methods of use
    Publication number: 20040166562
    Abstract: A serum-free C3A clonal cell line and methods for generating the same are provided. The C3A cell line has a reduced doubling time in serum-free medium compared to a corresponding C3A cell line from which it is derived. Methods using the cells of the serum-free C3A clonal cell line for the production, expression and recovery of harvestable polypeptides, screening compounds for metabolic activity, studying enteric disease and for use in a bio-artificial liver device are also provided.
    Type: Application
    Filed: November 25, 2003
    Publication date: August 26, 2004
    Inventors: Dennis Triglia, Anthony Purchio
  • Clonal cells and cell lines derived from C3A cells and methods of making and using them
    Patent number: 6653105
    Abstract: A serum-free C3A clonal cell line and methods for generating the same are provided. The C3A cell line has a reduced doubling time in serum-free medium compared to a corresponding C3A cell line from which it is derived. Methods using the cells of the serum-free C3A clonal cell line for the production, expression and recovery of harvestable polypeptides, screening compounds for metabolic activity, studying enteric disease and for use in a bio-artificial liver device are also provided.
    Type: Grant
    Filed: February 11, 1998
    Date of Patent: November 25, 2003
    Assignee: Vitagen, Inc.
    Inventors: Dennis Triglia, Anthony Purchio
  • Isolation and identification of mouse and human transcription control elements associated with cytochrome expression
    Publication number: 20030145341
    Abstract: The present invention relates to transcription control elements derived from mouse and human genes associated with cytochrome expression, e.g., Cyp3A11 and CYP3A4, respectively. Isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, may comprise such transcription control elements as described herein.
    Type: Application
    Filed: April 11, 2002
    Publication date: July 31, 2003
    Inventors: Weisheng Zhang, Pamela Contag, Anthony Purchio, Sandy Hashima, Shirley Ma, Kevin Nawotka
  • Isolation and identification of transcription control elements associated with mouse eosinophil peroxidase expression
    Publication number: 20030005472
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. Such transcription control elements may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals, as described herein.
    Type: Application
    Filed: April 19, 2002
    Publication date: January 2, 2003
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt
  • C3A SERUM-FREE CLONAL CELL LINE AND METHODS OF USE
    Publication number: 20020012654
    Abstract: A serum-free C3A clonal cell line and methods for generating the same are provided. The C3A cell line has a reduced doubling time in serum-free medium compared to a corresponding C3A cell line from which it is derived. Methods using the cells of the serum-free C3A clonal cell line for the production, expression and recovery of harvestable polypeptides, screening compounds for metabolic activity, studying enteric disease and for use in a bio-artificial liver device are also provided.
    Type: Application
    Filed: February 11, 1998
    Publication date: January 31, 2002
    Inventors: DENNIS TRIGLIA, ANTHONY PURCHIO
  • Vaccines against melanoma
    Patent number: 5141742
    Abstract: Peptides or proteins related to a melanoma associated antigen are described. These are produced in large quantities via recombinant DNA techniques and/or by chemical synthetic methods. The peptides or proteins can be used as immunogens in vaccine formulations which can induce an immune response that selectively destroys melanoma cells in a vaccinated individual. Where the peptides or proteins are expressed by a recombinant virus, inactivated or live virus vaccine formulations may be prepared.
    Type: Grant
    Filed: May 13, 1991
    Date of Patent: August 25, 1992
    Assignee: Oncogen
    Inventors: Joseph P. Brown, Charles D. Estin, Gregory D. Plowman, Timothy M. Rose, Karl E. Hellstrom, Ingegerd Hellstrom, Anthony Purchio, Shiu-Lok Hu, Sridhar Pennathur