Abstract: A flow cell incorporates a first substrate with a metal layer on one surface. A tape layer having flow channels is adhered to the first substrate. A second substrate having a second metal layer on one surface is adhered to the tape layer opposite the first substrate. At least one of the first and second metal layers includes mating cutouts to at least partially expose the flow channels.

Abstract: A flow cell incorporates a first substrate with a metal layer on one surface. A tape layer having flow channels is adhered to the first substrate. A second substrate having a second metal layer on one surface is adhered to the tape layer opposite the first substrate. At least one of the first and second metal layers includes mating cutouts to at least partially expose the flow channels.

Abstract: A flow cell incorporates a first substrate with a metal layer on one surface. A tape layer having flow channels is adhered to the first substrate. A second substrate having a second metal layer on one surface is adhered to the tape layer opposite the first substrate. At least one of the first and second metal layers includes mating cutouts to at least partially expose the flow channels.

Abstract: A flow cell incorporates a first substrate with a metal layer on one surface. A tape layer having flow channels is adhered to the first substrate. A second substrate having a second metal layer on one surface is adhered to the tape layer opposite the first substrate. At least one of the first and second metal layers includes mating cutouts to at least partially expose the flow channels.

Abstract: A device for analyzing a maternal blood sample for quantification of the percentage of fetal red blood cells present with respect to the number of maternal red blood cells includes reagents for mixing with the biological sample, a microfluidic chip, 5 fluid reservoirs, a pumping system, an image acquisition system, an image analysis system, and an electronic control board. The microfluidic channel can confine the objects of interest to a monolayer, and may trap them in an organized array for analysis. The device uses a reduced sample volume and microfluidic pumping and imaging techniques throughout. The disclosed invention holds distinct advantages over the current state of the art in fetal red blood cell quantification in a maternal blood sample by producing faster results, removing operator error, reducing 10 costs, and providing overall simplification of the testing and analysis procedure.

Abstract: A method for fabrication of a locomotive diesel engine turbocharger turbine stage so as to avoid harmonic vibration in the turbine blades when the engine is operated at pre-selected throttle settings. Upon determining throttle settings for the engine and modeling of the turbocharger therefor, at least one natural vibration frequency of the turbine blades and a turbine nozzle vane excitation frequency as a function of turbocharger rotation speed are determined. Then the data obtained is analyzed to ascertain whether at least one data coincidence, that is whether a rotation speed correlative of a throttle setting has a coincidence over a predetermined range of both a natural frequency and said turbine vane nozzle excitation. If not, the model is suitable for fabrication of the turbocharger; if so, the model is modified by changing blade stiffness and/or vane numbering until no data coincidences are present.