Patents by Inventor Anthony Tomlinson

Anthony Tomlinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION AND METHODS FOR STABILIZING LIQUID PROTEIN FORMULATIONS
    Publication number: 20240123066
    Abstract: The present disclosure provides liquid formulations comprising polypeptides and surfactants. In particular, it discloses a liquid formulation comprising a polypeptide and a surfactant, wherein at least about 70% (wt %) of the surfactant are isosorbide polyoxyethylene (POE) fatty acid esters. The invention also provides methods for making such liquid formulations, articles of manufacture comprising such liquid formulations and methods of treating a patient with such liquid formulations.
    Type: Application
    Filed: December 6, 2023
    Publication date: April 18, 2024
    Applicant: Genentech, Inc.
    Inventors: Anthony TOMLINSON, Barthelemy Luc DEMEULE, Isidro Angelo Eleazar ZARRAGA
  • Polysorbate Mixtures Having Modified Fatty Acid Ester Distribution
    Publication number: 20240050572
    Abstract: The present disclosure provides polysorbate 20 compositions with particular fatty acid ester concentrations. In some embodiments, they may be used in pharmaceutical formulations, for example, to improve stability.
    Type: Application
    Filed: October 26, 2023
    Publication date: February 15, 2024
    Applicant: Genentech, Inc.
    Inventors: Sandeep Yadav, Nidhi Doshi, Tomanna Shobha, Anthony Tomlinson, Amit Srivastava
  • Composition and methods for stabilizing liquid protein formulations
    Patent number: 11865177
    Abstract: The present disclosure provides liquid formulations comprising polypeptides and surfactants. In particular, it discloses a liquid formulation comprising a polypeptide and a surfactant, wherein at least about 70% (wt %) of the surfactant are isosorbide polyoxyethylene (POE) fatty acid esters. The invention also provides methods for making such liquid formulations, articles of manufacture comprising such liquid formulations and methods of treating a patient with such liquid formulations.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: January 9, 2024
    Assignee: GENENTECH, INC.
    Inventors: Anthony Tomlinson, Barthelemy Luc Demeule, Isidro Angelo Eleazar Zarraga
  • Polysorbate mixtures having modified fatty acid ester distribution
    Patent number: 11833206
    Abstract: The present disclosure provides polysorbate 20 compositions with particular fatty acid ester concentrations. In some embodiments, they may be used in pharmaceutical formulations, for example, to improve stability.
    Type: Grant
    Filed: September 23, 2021
    Date of Patent: December 5, 2023
    Assignee: Genentech, Inc.
    Inventors: Sandeep Yadav, Nidhi Doshi, Tamanna Shobha, Anthony Tomlinson, Amit Srivastava
  • POLYSORBATE MIXTURES HAVING MODIFIED FATTY ACID ESTER DISTRIBUTION
    Publication number: 20220111054
    Abstract: The present disclosure provides polysorbate 20 compositions with particular fatty acid ester concentrations. In some embodiments, they may be used in pharmaceutical formulations, for example, to improve stability.
    Type: Application
    Filed: September 23, 2021
    Publication date: April 14, 2022
    Applicant: Genentech, Inc.
    Inventors: Sandeep Yadav, Nidhi Doshi, Tamanna Shobha, Anthony Tomlinson, Amit Srivastava
  • MODIFIED MAMMALIAN CELLS
    Publication number: 20210309989
    Abstract: The present disclosure relates to methods, cells, and compositions for producing a product of interest, e.g., a recombinant protein. In particular, the present disclosure provides improved mammalian cells expressing the product of interest, where the cells (e.g., Chinese Hamster Ovary (CHO) cells) have reduced or eliminated activity, e.g., expression, of certain host cell proteins, e.g., enzymes including, but not limited to, certain lipases, esterases, and/or hydrolases.
    Type: Application
    Filed: March 26, 2021
    Publication date: October 7, 2021
    Applicant: GENENTECH, INC.
    Inventors: Michael Wilson LAIRD, Shahram MISAGHI, Amy SHEN, Anthony TOMLINSON, Inn Huam YUK
  • COMPOSITION AND METHODS FOR STABILIZING LIQUID PROTEIN FORMULATIONS
    Publication number: 20210015920
    Abstract: The present disclosure provides liquid formulations comprising polypeptides and surfactants. In particular, it discloses a liquid formulation comprising a polypeptide and a surfactant, wherein at least about 70% (wt %) of the surfactant are isosorbide polyoxyethylene (POE) fatty acid esters. The invention also provides methods for making such liquid formulations, articles of manufacture comprising such liquid formulations and methods of treating a patient with such liquid formulations.
    Type: Application
    Filed: June 26, 2020
    Publication date: January 21, 2021
    Applicant: Genentech, Inc.
    Inventors: Anthony TOMLINSON, Barthelemy Luc DEMEULE, Isidro Angelo Eleazar ZARRAGA
  • Method for preparing polyamine compounds
    Patent number: 8692031
    Abstract: A method for preparing a compound having formula (II) wherein R1 and R2 independently are methyl or ethyl, or R1 and R2 combine to form a C5 or C6 cycloalkyl or cycloalkenyl group. The method includes a step of combining R1R2CHNO2, glutaraldehyde and an amine. The compound is useful in coating compositions and other applications for pH adjustment.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: April 8, 2014
    Assignees: Dow Global Technologies LLC, ANGUS Chemical Company
    Inventors: Ian Anthony Tomlinson, Glenn Nelson Robinson, Asghar Akber Peera
  • METHOD FOR PREPARING POLYAMINE COMPOUNDS
    Publication number: 20120202934
    Abstract: A method for preparing a compound having formula (II) wherein R1 and R2 independently are methyl or ethyl, or R1 and R2 combine to form a C5 or C6 cycloalkyl or cycloalkenyl group. The method includes a step of combining R1R2CHNO2, glutaraldehyde and an amine. The compound is useful in coating compositions and other applications for pH adjustment.
    Type: Application
    Filed: October 8, 2010
    Publication date: August 9, 2012
    Inventors: Ian Anthony Tomlinson, Glenn Nelson Robinson, Asghar Akber Peera
  • Alkylation process
    Patent number: 7030285
    Abstract: A side-chain of a substituted aromatic compound is alkylated by reacting the aromatic compound with an alkylating agent in the presence of a catalyst. The catalyst comprises a restructured smectite clay to which basic ions are incorporated by ion-exchange. The restructuring of the smectite clay is carried out by acid-treating the clay prior to ion-exchange.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: April 18, 2006
    Assignee: Optatech Corporation
    Inventors: Adriana De Stefanis, Giorgio Perez, Anthony Tomlinson, Christer Bergst{umlaut over (r)}öm
  • Alkylation process
    Publication number: 20030023124
    Abstract: This invention concerns an alkylation process. According to the process a side-chain of a substituted aromatic compound is alkylated by reacting the aromatic compound with an alkylating agent in the presence of a catalyst. According to the invention, the catalyst comprises a restructured smectite clay to which basic ions are incorporated by ion-exchange.
    Type: Application
    Filed: July 24, 2002
    Publication date: January 30, 2003
    Inventors: Adriana De Stefanis, Giorgio Perez, Anthony Tomlinson, Christer Bergstrom