Abstract: The present disclosure relates to designs and applications of Variable Heavy Only (VHO) domain regions. The present disclosure provides a VHO library of polynucleotides encoding VHO domains, wherein the VHO domains are designed based on the Vh domain of a human Vh family, and a method of generating the VHO library. The present disclosure also provides a phage library displaying the VHO domains encoded by the VHO library through the use of M13 bacteriophage minor coat proteins such as pIX and pVII and a method of generating the phage library. The present disclosure also provides a method of screening the phage library to identify VHO candidates that are capable of binding a target of interest.

Abstract: The present invention generally relates to covering for a window sill, a fireplace mantel or ledge. The covering can be used for the purpose of decoration. The covering can be used for the purpose of protection. The covering can be used for the purpose of energy savings. The present invention relates to a covering comprising a core material, enclosed by a cover having a first portion which encloses the core and a second portion which extends downward from first portion.

Abstract: A routing module applies a plurality of routing rules simultaneously to determine routing for a Fibre Channel frame. Each rule independently determines whether the rule applies to the frame as well as a routing result for the frame. The routing result includes a port address, a zoning indicator, and a priority designation that can be used to route the frame over a virtual channel in an interswitch link. A selector chooses between the results returned by the rules. A component receives routing results specifying an ISL group and selects a physical ISL for the frame. An in-band priority determined by the content of the frame header can also be used in place of the priority designation in the routing result.

Abstract: A method and apparatus is disclosed for temporarily deferring transmission of frames to a destination in a data switch. When a request for transmission of a frame to the destination port is received, the congestion status of that destination is determined. If the destination is congested, the frame is stored in a deferred queue. When the status of a destination changes from congested to non-congested, the deferred queue is examined to see if any deferred frames can now be forwarded to their destination. While examining the deferred queue, incoming frames are placed on a backup queue. When the deferred queue is fully analyzed, the backup queue is emptied by either sending those frames to their destination or storing the frames in the deferred queue. While examining the deferred queue, the congested states of the destinations are not allowed to change from congested to non-congested.

Abstract: A congestion notification mechanism provides a congestion status for all destinations in a switch at each ingress port. Data is stored in a memory subsystem queue associated with the destination port at the ingress side of the crossbar. A cell credit manager tracks the amount of data in this memory subsystem for each destination. If the count for any destination exceeds a threshold, the credit manager sends an XOFF signal to the XOFF masks. A lookup table in the XOFF masks maintains the status for every switch destination based on the XOFF signals. An XON history register receives the XOFF signals to allow queuing procedures that do not allow a status change to XON during certain states. Flow control signals directly from the memory subsystem are allowed to flow to each XOFF mask, where they are combined with the lookup table status to provide a congestion status for every destination.

Abstract: A Fibre Channel switch is presented that tracks the congestion status of destination ports in an XOFF mask at each input. A mapping is maintained between virtual channels on an ISL and the destination ports to allow changes in the XOFF mask to trigger a primitive to an upstream port that provides virtual channel flow control. The XOFF mask is also used to avoid sending frames to a congested port. Instead, these frames are stored on a single deferred queue and later processed in a manner designed to maintain frame ordering. A routing system is provided that applies multiple routing rules in parallel to perform line speed routing. The preferred switch fabric is cell based, with techniques used to manage path maintenance for variable length frames and to adapt to varying transmission rates in the system. Finally, the switch allows data and microprocessor communication to share the same crossbar network.