Patents by Inventor Anthony TUTINO

Anthony TUTINO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulations of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
    Patent number: 9468605
    Abstract: Pharmaceutical compositions and single unit dosage forms of apremilast, i.e., (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as diseases or disorders ameliorated by the inhibition of TNF-? production in mammals.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: October 18, 2016
    Assignee: Celgene Corporation
    Inventors: Darshan K. Parikh, Anil Menon, Anthony Tutino
  • Pharmaceutical compositions of cytidine analogs and methods of use thereof
    Patent number: 9393255
    Abstract: The present disclosure provides pharmaceutical compositions comprising cytidine analogs for parenteral administration. Also provided are methods of preparing the compositions and methods of treating diseases and disorders using the compositions provided herein.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: July 19, 2016
    Assignee: Celgene Corporation
    Inventors: Anthony Tutino, Mei Lai, Jeffrey B. Etter
  • Pharmaceutical formulations of a substituted diaminopurine
    Patent number: 9198866
    Abstract: Provided herein are pharmaceutical formulations, comprising 4-((9-((3S)-tetrahydro-3-furanyl)-8-((2,4,6-trifluorophenyl)amino)-9H-purin-2-yl)amino)-trans-cyclohexanol, including pharmaceutically acceptable salts, solvates, isomers, isotopologues, tautomers and racemic mixtures thereof, and a pharmaceutically acceptable excipient; and their use for treating or preventing disease.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: December 1, 2015
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Sreenivas S. Bhat, Xiaozhong Liang, Anthony Tutino, Anthony Joseph Frank
  • FORMULATIONS OF (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOISOINDOLINE-1,3-DIONE
    Publication number: 20140370092
    Abstract: Pharmaceutical compositions and single unit dosage forms of apremilast, i.e., (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as diseases or disorders ameliorated by the inhibition of TNF-? production in mammals.
    Type: Application
    Filed: June 16, 2014
    Publication date: December 18, 2014
    Inventors: Darshan K. Parikh, Anil Menon, Anthony Tutino
  • Formulations of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione
    Patent number: 8828427
    Abstract: Pharmaceutical compositions and single unit dosage forms of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as cancer or an inflammatory disease.
    Type: Grant
    Filed: May 19, 2010
    Date of Patent: September 9, 2014
    Assignee: Celgene Corporation
    Inventors: Anthony Tutino, Michael T. Kelly
  • PHARMACEUTICAL FORMULATIONS OF A SUBSTITUTED DIAMINOPURINE
    Publication number: 20140093566
    Abstract: Provided herein are pharmaceutical formulations, comprising 4-((9-((3S)-tetrahydro-3-furanyl)-8-((2,4,6-trifluorophenyl)amino)-9H-purin-2-yl)amino)-trans-cyclohexanol, including pharmaceutically acceptable salts, solvates, isomers, isotopologues, tautomers and racemic mixtures thereof, and a pharmaceutically acceptable excipient; and their use for treating or preventing disease.
    Type: Application
    Filed: November 8, 2013
    Publication date: April 3, 2014
    Applicant: Signal Pharmaceuticals, LLC
    Inventors: Sreenivas S. Bhat, Xiaozhong Liang, Anthony Tutino, Anthony Joseph Frank
  • Pharmaceutical formulations of a substituted diaminopurine
    Patent number: 8603527
    Abstract: Provided herein are pharmaceutical formulations, comprising 4-((9-((3S)-tetrahydro-3-furanyl)-8-((2,4,6-trifluorophenyl)amino)-9H-purin-2-yl)amino)-trans-cyclohexanol, including pharmaceutically acceptable salts, solvates, isomers, isotopologues, tautomers and racemic mixtures thereof, and a pharmaceutically acceptable excipient; and their use for treating or preventing disease.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: December 10, 2013
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Sreenivas S. Bhat, Xiaozhong Liang, Anthony Tutino, Anthony Joseph Frank
  • PHARMACEUTICAL COMPOSITIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF
    Publication number: 20120196823
    Abstract: The present disclosure provides pharmaceutical compositions comprising cytidine analogs for parenteral administration. Also provided are methods of preparing the compositions and methods of treating diseases and disorders using the compositions provided herein.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 2, 2012
    Applicant: Celgene Corporation
    Inventors: Anthony TUTINO, Mei LAI, Jeffrey B. ETTER
  • PHARMACEUTICAL FORMULATIONS OF A SUBSTITUTED DIAMINOPURINE
    Publication number: 20120100213
    Abstract: Provided herein are pharmaceutical formulations, comprising 4-((9-((3S)-tetrahydro-3-furanyl)-8-((2,4,6-trifluorophenyl)amino)-9H-purin-2-yl)amino)-trans-cyclohexanol, including pharmaceutically acceptable salts, solvates, isomers, isotopologues, tautomers and racemic mixtures thereof, and a pharmaceutically acceptable excipient; and their use for treating or preventing disease.
    Type: Application
    Filed: October 20, 2011
    Publication date: April 26, 2012
    Inventors: Sreenivas S. Bhat, Xiaozhong Liang, Anthony Tutino, Anthony Joseph Frank
  • FORMULATIONS OF 4-AMINO-2-(2,6-DIOXOPIPERIDINE-3-YL)ISOINDOLINE-1,3-DIONE
    Publication number: 20110045064
    Abstract: Pharmaceutical compositions and single unit dosage forms of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as cancer or an inflammatory disease.
    Type: Application
    Filed: May 19, 2010
    Publication date: February 24, 2011
    Inventors: Anthony TUTINO, Michael T. Kelly