Abstract: Disclosed herein are biocompatible materials useful for tissue regeneration and repair, wherein the bioactive polymer may be in the form of a hydrogel, for example a thermoresponsive hydrogel. This bioactive polymer and a resulting hydrogel, may be used for the regeneration of bone tissue. Accordingly, also disclosed herein are methods of treating a bone defect in a mammal, the methods comprising administering a therapeutically effective amount of a hydrogel formed by the bioactive polymer to the mammal to treat the bone defect.

Abstract: Disclosed herein are biocompatible materials useful for tissue regeneration and repair, wherein the bioactive polymer may be in the form of a hydrogel, for example a thermoresponsive hydrogel. This bioactive polymer and a resulting hydrogel, may be used for the regeneration of bone tissue. Accordingly, also disclosed herein are methods of treating a bone defect in a mammal, the methods comprising administering a therapeutically effective amount of a hydrogel formed by the bioactive polymer to the mammal to treat the bone defect.

Abstract: Disclosed herein are biocompatible materials useful for tissue regeneration and repair, wherein the bioactive polymer may be in the form of a hydrogel, for example a thermoresponsive hydrogel. This bioactive polymer and a resulting hydrogel, may be used for the regeneration of bone tissue. Accordingly, also disclosed herein are methods of treating a bone defect in a mammal, the methods comprising administering a therapeutically effective amount of a hydrogel formed by the bioactive polymer to the mammal to treat the bone defect.

Abstract: Methods for fumigating soil include applying over fumigant-treated soil a multilayer polymeric film to form a vapor barrier between the fumigant-treated soil and the atmosphere to at least partially contain the fumigant. The multilayer film includes at least one barrier layer comprising at least one vinylidene chloride polymer and protecting layers on each side of the barrier layer. The multilayer film preferably has at least one UV protecting layer and optionally at least one reflective layer.

Abstract: Methods for fumigating soil include applying over fumigant-treated soil a multilayer polymeric film to form a vapor barrier between the fumigant-treated soil and the atmosphere to at least partially contain the fumigant. The multilayer film includes at least one barrier layer comprising at least one vinylidene chloride polymer and protecting layers on each side of the barrier layer. The multilayer film preferably has at least one UV protecting layer and optionally at least one reflective layer.

Abstract: Equipment for the placement or positioning of one or more items in or on the ground is provided. In one form, an apparatus includes a toolbar, a container, a metering unit configured to selectively control release of one or more items from the container and an application member configured to deliver the one or more items released from the container to the ground. In one aspect of this form, the metering unit is configured to selectively control release of one or more spherical items having a diameter in the range of about 0.25 inches to about 1.0 inches, and more particularly, but not exclusively, in the range of about 0.5 inches to about 0.75 inches, from the container to the application member. In another more particular aspect, the spherical items are capsules that include a shell wall encapsulating a pesticide composition and including a gelatin material.

Abstract: Methods for fumigating soil include providing a fumigant including at least one volatile substance into or onto soil and applying over the soil a multilayer polymeric film to form a vapor barrier between the fumigant-treated soil and the atmosphere to at least partially contain the fumigant. The multilayer film includes at least one barrier layer comprising at least one vinylidene chloride polymer and protecting layers on each side of the barrier layer. The multilayer film preferably has at least one UV protecting layer and optionally at least one reflective layer.

Abstract: Methods for fumigating soil include providing a fumigant including at least one volatile substance into or onto soil and applying over the soil a multilayer polymeric film to form a vapor barrier between the fumigant-treated soil and the atmosphere to at least partially contain the fumigant. The multilayer film includes at least one barrier layer comprising at least one vinylidene chloride polymer and protecting layers on each side of the barrier layer. The multilayer film preferably has at least one UV protecting layer and optionally at least one reflective layer.

Abstract: Equipment for the placement or positioning of one or more items in or on the ground is provided. In one form, an apparatus includes a toolbar, a container, a metering unit configured to selectively control release of one or more items from the container and an application member configured to deliver the one or more items released from the container to the ground. In one aspect of this form, the metering unit is configured to selectively control release of one or more spherical items having a diameter in the range of about 0.25 inches to about 1.0 inches, and more particularly, but not exclusively, in the range of about 0.5 inches to about 0.75 inches, from the container to the application member. In another more particular aspect, the spherical items are capsules that include a shell wall encapsulating a pesticide composition and including a gelatin material.

Abstract: Methods for fumigating soil include providing a fumigant including at least one volatile substance into or onto soil and applying over the soil a multilayer polymeric film to form a vapor barrier between the fumigant-treated soil and the atmosphere to at least partially contain the fumigant. The multilayer film includes at least one barrier layer comprising at least one vinylidene chloride polymer and protecting layers on each side of the barrier layer. The multilayer film preferably has at least one UV protecting layer and optionally at least one reflective layer.

Abstract: Biocompatible materials suitable for use in vascular applications have been engineered, combining human recombinant tropoelastin with other synthetic or natural biomaterials to form protoelastin. The materials can be in the form of elastin films on metal, bone, ceramic or polymer substrates, laminates of alternating polymer and elastin, blends of polymer and elastin, or elastin crosslinked with or tethered to polymer. The flexibility in engineering and design makes protoelastin biomaterials suited not only to the production of conduits but any number of other vascular applications that require blood contacting surfaces. Tropoelastin and the subsequently engineered biomaterial protoelastin provide the opportunity to satisfy a large unmet need for a biocompatible material adaptable enough to meet a range of diverse vascular uses. These are mechanically stable, elastic, strong and biocompatible (i.e., not thrombogenic and promoting adhesion of cells, especially human endothelial cells.

Abstract: The manipulation of the amino acid sequence of tropoelastin, particularly human tropoelastin, to modify its protease susceptibility is described. The modified tropoelastins include tropoelastin derivatives having modified protease susceptibility, peptidomimetic molecules which contain amino acid sequences which correspond to or incorporate the protease susceptible sequences of tropoelastin. Uses of these tropoelastin derivatives and peptidomimetic molecules are provided. Also provided are nucleic acid molecules and genetic constructs encoding the amino acid sequences of the derivatives and peptidomimetic molecules of the invention.

Abstract: The invention relates to derivatives of tropoelastin and variants of those derivatives. The invention further provides expression products and hybrid molecules of the derivatives and variants of the invention. The invention further provides methods for the production of the derivatives, variants, expression products and hybrid molecules. Further provided are formulations, cross-linked structures and implants comprising the derivatives, variants, expression products and hybrid molecules of the invention. Further provided are uses of the derivatives, variants, expression products and hybrid molecules of the invention.

Abstract: The invention relates to derivatives of tropoelastin and variants of those derivatives. The invention further provides expression products and hybrid molecules of the derivatives and variants of the invention. The invention further provides methods for the production of the derivatives, variants, expression products and hybrid molecules. Further provided are formulations, cross-linked structures and implants comprising the derivatives, variants, expression products and hybrid molecules of the invention. Further provided are uses of the derivatives, variants, expression products and hybrid molecules of the invention.

Abstract: A communication system comprises a reference base station which collects one or more signal features of a mobile station signal. The reference base station determines a first location parameter of the mobile station signal it receives. The reference base station forwards the signal features to an auxiliary base station. Using the signal features, the auxiliary base station creates a replica of the mobile station signal as transmitted by the mobile station. The auxiliary base station correlates the replica with a same mobile station signal as received at the auxiliary base station in order to determine a second set of signal features. The auxiliary base station uses the second set of signal features to determine a second location parameter. The position of the mobile station is determined using the first and second location parameters.

Abstract: A communication system comprises a reference base station which collects one or more signal features of a mobile station signal. The reference base station determines a first location parameter of the mobile station signal it receives. The reference base station forwards the signal features to an auxiliary base station. Using the signal features, the auxiliary base station creates a replica of the mobile station signal as transmitted by the mobile station. The auxiliary base station correlates the replica with a same mobile station signal as received at the auxiliary base station in order to determine a second set of signal features. The auxiliary base station uses the second set of signal features to determine a second location parameter. The position of the mobile station is determined using the first and second location parameters.