Abstract: The invention provides anti-IFNAR1 antibodies with reduced affinity for Fc receptors and/or ligands and methods of making and using such antibodies.

Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Nav1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Nav1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.

Abstract: A method is provided for remotely assuring the quality and transportation of offsite construction components. The method involves placing a code on the module, where the code contains identity information about the module. Then the code is scanned to obtain the identity information and to upload it to a blockchain data storage facility. Access is allowed to the identity information in the blockchain data storage facility to relevant parties for the purpose of remotely inspecting the module to verify its quality. Based on this verification the module may be delivered to a transportation facility for transport. During transport location information about the module is collected and uploading it to blockchain data storage facility. Second access is allowed to the location information stored in the blockchain data storage facility to allow relevant parties to remotely understand the transportation situation of the module.

Abstract: A base comprising a clamp opening on its top surface; channels on its bottom surface; and a through hole from the bottom surface to the top surface; in a safety system, the clamp receiving an end of a post secured to the clamp using a fastener inserted from one of the side walls of the base, into abutment with the post in the clamp; and/or the channels guiding posts on the bottom surface; and/or the channels guiding posts to a connector on the bottom surface; or a first channel guiding a first post to a connector on the bottom surface and a channel guiding a second post to the connector; and/or the through hole receives the post inserted therethrough thus extending on each side of the base.

Abstract: An electronic device may have a cover layer and an antenna. A dielectric adapter may have a first surface coupled to the antenna and a second surface pressed against the cover layer. The cover layer may have a three-dimensional curvature. The second surface may have a curvature that matches the curvature of the cover layer. Biasing structures may exert a biasing force that presses the antenna against the dielectric adapter and that presses the dielectric adapter against the cover layer. The biasing force may be oriented in a direction normal to the cover layer at each point across dielectric adapter. This may serve to ensure that a uniform and reliable impedance transition is provided between the antenna and free space through the cover layer over time, thereby maximizing the efficiency of the antenna.

Abstract: MF (Magnet Football) board game is a simulation of the real game of football. Decorated magnets are used to simulate football players for offense and defense players playing under the pressure of a digital game clock timer. Defense player is timed by digital clock timer to strategically create barriers using decorated defense magnets creating barriers within time allowed under the digital clock timer, once the timer is exhausted unused defense magnets may not be used for play result in weaker defense barrier. Timed by the digital clock timer offense player is to maneuver with finger(s) on top of offense magnet and direct the offense magnet avoiding being tackled by defense magnets (tackled is when defense magnets attracts to offense magnets) result in a down. MF has three methods to score points, touchdown, field goal kick, and two point conversion.

Abstract: A framework for integrating applications using the Workflow Toolkit provides a graphical development environment for developing an Extensible Workflow. The Workflow Toolkit may include a user interface displaying a first list of application programming interface (API) services provided by a first application and a second list of API services provided by a second application. The Workflow Toolkit may then generate an integration component in response to a user selecting both a first API service from the first list and a second API service from the second list. The integration component can then be called from the first API service, and the integration component in turn calls the second API service. In response to the second API service being called, the second API service may return a result. When this result is received by the integration component, the integration component may return an integration result based on the result received from the second API.

Abstract: A framework for integrating applications using the Workflow Toolkit provides a graphical development environment for developing an Extensible Workflow. The Workflow Toolkit may include a user interface displaying a first list of application programming interface (API) services provided by a first application and a second list of API services provided by a second application. The Workflow Toolkit may then generate an integration component in response to a user selecting both a first API service from the first list and a second API service from the second list. The integration component can then be called from the first API service, and the integration component in turn calls the second API service. In response to the second API service being called, the second API service may return a result. When this result is received by the integration component, the integration component may return an integration result based on the result received from the second API.

Abstract: A router in a network comprises an interface system for receiving packets and has a plurality of channels and a plurality of framing service engines. The router is configured to assign the channels to individual framing service engines for framing services. The router has a channel manager for performing the assignments, and the channel manager is configured to receive and use data about the framing service engines. The router further comprises a framing memory for buffering communication between the interface system and the plurality of framing service engines. At least one framing service engine is configured to frame packets and at least one framing service engine is configured to deframe packets, and the framing service engines may be configured to operate on AHDLC packets. The router can be used with an interface system that comprises a plurality of network interfaces terminating a plurality of point to point links.

Abstract: An ultrasound information processing system is disclosed in which ultrasound image data is packetized into ultrasound information packets and routed to one or more of a plurality of processors for performing image processing operations on the ultrasound image data, the ultrasound information packets being routed according to entries in a host-programmable routing table. A common distribution bus is coupled between packetizing circuitry and dedicated input buffers corresponding to each processor for distributing the ultrasound information packets, and a common output bus to is used to transfer processed image data from the processors to an output device. The disclosed ultrasound information processing system architecture allows for a high throughput rate for accommodating real-time image processing operations, while also allowing for ready programmability and upgradability.

Abstract: A magnetic recording disk with a glass substrate is textured by a process which creates an array of bumps in a magnetic head contact start and stop (CSS) region of the disk. The texturing process uses a laser to provide pulses of predetermined energy fluence on the glass substrate to produce a plurality of raised bumps in the substrate surface, each bump having a surface elevation controllable to within a few nanometers. The bumps are created without unwanted micro-cracking or ejection of surface material by exploiting a narrow operating region below the abrupt thermal shock fluence threshold of the glass substrate. This textured glass substrate provides the magnetic recording disk with improved stiction, wear, coatability and sensor flying height properties.

Abstract: A process for creating an array of bumps to texture a brittle nonmetallic surface, such as a glass substrate for data recording disks. The texturing process uses a laser to provide pulses of proper energy fluence to the brittle glass surface to produce a plurality of raised bumps in the surface. The bump creation is accomplished without unwanted micro-cracking or ejection of surface material by limiting the laser pulse fluence to a value in a narrow operating region discovered below the abrupt thermal shock fluence threshold for the brittle nonmetallic surface material. The process is also applicable to other brittle surface textures, such as those intended for use as "stamping surfaces" for the contact reproduction of the negative of a surface pattern, such as an optical disk.

Abstract: A process for creating an array of bumps to texture a brittle nonmetallic surface, such as a glass substrate for data recording disks. The texturing process uses a laser to provide pulses of proper energy fluence to the brittle glass surface to produce a plurality of raised bumps in the surface. The bump creation is accomplished without unwanted micro-cracking or ejection of surface material by limiting the laser pulse fluence to a value in a narrow operating region discovered below the abrupt thermal shock fluence threshold for the brittle nonmetallic surface material. The process is also applicable to other brittle surface textures, such as those intended for use as "stamping surfaces" for the contact reproduction of the negative of a surface pattern, such as an optical disk.