Patents by Inventor Antimo Migliaccio

Antimo Migliaccio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-androgen peptides and uses thereof in cancer therapy
    Patent number: 11560406
    Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: January 24, 2023
    Assignee: CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Ferdinando Auricchio, Antimo Migliaccio
  • Modulators of the SRC-kinase activity for preventing or treating metastatic cancer
    Patent number: 10400008
    Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: September 3, 2019
    Assignee: Cancer Research Technology Limited
    Inventors: Satu Vainikka, George Steven Morris, Samuel Ogunsalu, Gabriella Castoria, Antimo Migliaccio, Ferdinando Auricchio
  • ANTI-ANDROGEN PEPTIDES AND USES THEREOF IN CANCER THERAPY
    Publication number: 20180271933
    Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.
    Type: Application
    Filed: March 12, 2018
    Publication date: September 27, 2018
    Inventors: Ferdinando AURICCHIO, Antimo Migliaccio
  • Anti-androgen peptides and uses thereof in cancer therapy
    Patent number: 9919023
    Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: March 20, 2018
    Assignee: Cancer Research Technology Limited
    Inventors: Ferdinando Auricchio, Antimo Migliaccio
  • MODULATORS OF THE SRC-KINASE ACTIVITY FOR PREVENTING OR TREATING METASTATIC CANCER
    Publication number: 20160068568
    Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].
    Type: Application
    Filed: April 30, 2014
    Publication date: March 10, 2016
    Inventors: Satu Vainikka, George Steven Morris, Samuel Ogunsalu, Gabriella Castoria, Antimo Migliaccio, Fernando Auricchio
  • ANTI-ANDROGEN PEPTIDES AND USES THEREOF IN CANCER THERAPY
    Publication number: 20150202249
    Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.
    Type: Application
    Filed: December 18, 2014
    Publication date: July 23, 2015
    Inventors: Ferdinando Auricchio, Antimo Migliaccio
  • ANTI-ANDROGEN PEPTIDES AND USES THEREOF IN CANCER THERAPY
    Publication number: 20100189776
    Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.
    Type: Application
    Filed: March 11, 2008
    Publication date: July 29, 2010
    Applicant: CANCER RESEARCH TECHNOLOGY LTD
    Inventors: Ferdinando Auricchio, Antimo Migliaccio