Abstract: Disclosed are methods to aid in a calibration of a vertical orientation of a nozzle tip to a sample container in a processing or testing system. The method includes positioning the nozzle over a calibration target at a home height location (HM), moving the nozzle downward a distance (D) until contact with the calibration target is sensed, positioning the nozzle over the sample rack and moving the nozzle downward until contact with a registration location is sensed, imaging the sample rack and calibration target to determine a height (H) between the registration location and calibration target, and calculating a translation ratio (TR) between the height (H) measured in pixel space and the distance (D) measured in machine space. The translation ratio (TR) may be used to drive the nozzle tip to a predetermined depth. A robot calibration system is disclosed, as are other aspects.

Abstract: Disclosed are methods to aid in a calibration of a vertical orientation of a nozzle tip to a sample container in a processing or testing system. The method includes positioning the nozzle over a calibration target at a home height location (HM), moving the nozzle downward a distance (D) until contact with the calibration target is sensed, positioning the nozzle over the sample rack and moving the nozzle downward until contact with a registration location is sensed, imaging the sample rack and calibration target to determine a height (H) between the registration location and calibration target, and calculating a translation ratio (TR) between the height (H) measured in pixel space and the distance (D) measured in machine space. The translation ratio (TR) may be used to drive the nozzle tip to a predetermined depth. A robot calibration system is disclosed, as are other aspects.

Abstract: A system for ultrasonic energy coupling includes an ultrasonic transducer, a horn member defining a passageway, and a pump for moving fluid through the passageway and outwardly of the horn. The method used to accomplish the energy coupling or transfer includes vibrating the horn member with an ultrasonic transducer and pumping fluid through the passageway in the horn member and onto an object.

Abstract: The present invention provides a waste removal assembly used in conjunction with a sampling system which provides access to a sealed container. The assembly includes a lifting mechanism which moves a sample container against a hollow cleaning needle. The needle penetrates the stopper of the container, and its penetrating end moves into the container proximate the inside surface of the stopper. The assembly also includes a pump and tube arrangement in communication with the needle for removing or displacing entrapped serum or other debris from the bottom surface of the stopper and placing it in a waste container. After removing the debris from the container, the cleaning assembly vents the cleaned container to atmospheric pressure, and the sampling system performs sampling operations through a puncture tube which defines a temporary opening in the stopper of the container.