Patents by Inventor Antoine MATHIEU
Antoine MATHIEU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970701Abstract: The invention relates to C. acnes carrying DNA vectors with a C. acnes phage packaging signal and a gene of interest. The invention encompasses a C. acnes producer cell carrying DNA vectors, with a C. acnes phage packaging signal and a gene of interest, for the production of phage-derived particles that can robustly transduce C. acnes receiver cell allowing transgene expression. The invention encompasses C. acnes phage-derived particles carrying these vectors, C. acnes containing these vectors or modified by transduction of these phage-derived particles, and methods of using these phage-derived particles.Type: GrantFiled: September 28, 2023Date of Patent: April 30, 2024Assignee: Eligo BioscienceInventors: Aymeric Leveau, Inès Canadas Blasco, Aurélie Mathieu, Antoine Decrulle
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Patent number: 11952595Abstract: The present invention concerns a production bacterial cell for producing lytic phage particles or lytic phage-derived delivery vehicles, said production bacterial cell stably comprising at least one phage structural genes and at least one phage DNA packaging genes, said phage structural gene(s) and phage DNA packaging gene(s) being derived from a lytic bacteriophage, wherein the expression of at least one of said phage structural genes and/or at least one of said phage DNA packaging gene(s) in said production bacterial cell is controlled by an induction mechanism.Type: GrantFiled: July 7, 2023Date of Patent: April 9, 2024Assignee: Eligo BioscienceInventors: Jesus Fernandez Rodriguez, Antoine Decrulle, Aymeric Leveau, Ines Canadas Blasco, Aurelie Mathieu, Thibault Carlier
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Patent number: 11939598Abstract: The present invention concerns a production bacterial cell for producing phage particles or phage-derived delivery vehicles, said production bacterial cell stably comprising at least one phage structural gene(s) and at least one phage DNA packaging gene(s), said phage structural gene(s) and phage DNA packaging gene(s) being derived from a first type of bacteriophage, wherein the expression of at least one of said phage structural gene(s) and/or at least one of said phage DNA packaging gene(s) in said production bacterial cell is controlled by at least one induction mechanism, and wherein said production bacterial cell is from a bacterial species or strain different from the bacterial species or strain from which said first type of bacteriophage comes and/or that said first type of bacteriophage targets.Type: GrantFiled: May 18, 2023Date of Patent: March 26, 2024Assignee: Eligo BioscienceInventors: Jesus Fernandez Rodriguez, Antoine Decrulle, Aymeric Leveau, Ines Canadas Blasco, Aurélie Mathieu, Thibault Carlier
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Patent number: 10816060Abstract: A reduction gear including an input shaft including an input gear, an output shaft including an output gear, and two intermediate transmission lines, each intermediate transmission line including an intermediate shaft including a first stage of teeth and a second stage of teeth, the stages rotating as one, and an additional gear for meshing respectively with the first stage of teeth and the input gear, or with the second stage of teeth and the output gear, and the reduction gear wherein the input gear or the output gear meshing with the additional gears is axially offset with respect to the stage of teeth of the intermediate shafts meshing with the additional gears.Type: GrantFiled: February 15, 2017Date of Patent: October 27, 2020Assignee: SAFRAN TRANSMISSION SYSTEMSInventors: Benjamin Feraud, Aldric Renaud Gabriel Marie Moreau De Lizoreux, Boris Morelli, Maxime Amiet, Antoine Mathieu
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Patent number: 10731748Abstract: A speed reducer includes two intermediate lines for a turboprop engine, the reducer including: an input line including an input shaft bearing an input gear wheel, a first intermediate line including a first intermediate shaft bearing a first intermediate gear wheel, a second intermediate line including a second intermediate shaft bearing a second intermediate gear wheel, a spring held by a frame, the spring surrounding a longitudinal portion of the input shaft in order to allow a movement of the input gear wheel towards an equilibrium position corresponding to an equal distribution of the transmission of the power coming from the input shaft to the first intermediate shaft of the first intermediate line and the second intermediate shaft of the second intermediate line.Type: GrantFiled: November 30, 2016Date of Patent: August 4, 2020Assignee: SAFRAN TRANSMISSION SYSTEMSInventors: Antoine Mathieu, Benjamin Feraud, Boris Pierre Marcel Morelli
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Patent number: 10443697Abstract: Speed reduction gear comprising two intermediate transmission lines, in particular for a turbine engine, comprising an input line (12) and an output line that is driven by the input line via said intermediate transmission lines, said intermediate transmission lines being substantially parallel, characterized in that said reduction gear comprises means for distributing loads between said intermediate lines, said load distribution means comprising swiveling coupling means (30) for rotatably coupling one end of the input line, and oil-damping means (40, 50) for damping radial movements of an opposite end of the input line.Type: GrantFiled: September 18, 2015Date of Patent: October 15, 2019Assignee: SAFRAN TRANSMISSION SYSTEMSInventors: Benjamin Feraud, Maxime Amiet, Guillaume Beck, Samuel Raymond Germain Becquerelle, Antoine Mathieu, Boris Morelli
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Publication number: 20190234490Abstract: A reduction gear including an input shaft including an input gear, an output shaft including an output gear, and two intermediate transmission lines, each intermediate transmission line including an intermediate shaft including a first stage of teeth and a second stage of teeth, the stages rotating as one, and an additional gear for meshing respectively with the first stage of teeth and the input gear, or with the second stage of teeth and the output gear, and the reduction gear wherein the input gear or the output gear meshing with the additional gears is axially offset with respect to the stage of teeth of the intermediate shafts meshing with the additional gears.Type: ApplicationFiled: February 15, 2017Publication date: August 1, 2019Applicant: SAFRAN TRANSMISSION SYSTEMSInventors: Benjamin FERAUD, Aldric Renaud Gabriel Marie MOREAU DE LIZOREUX, Boris MORELLI, Maxime AMIET, Antoine MATHIEU
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Publication number: 20180372197Abstract: The invention relates to a speed reducer (10) with two intermediate transmission lines (16), in particular for a turbine engine, including an input line (12) and an output line (14) driven by the input line via said intermediate lines, said intermediate lines being substantially parallel, characterised in that it includes load-distribution means between said intermediate lines, said load-distribution means comprising ball-and-socket means (30) for rotatably coupling a first end of the input line, first means (34) for damping the radial movements of said end of the input line, and second means (34) for damping the radial movements of a second opposite end of the input line.Type: ApplicationFiled: September 20, 2016Publication date: December 27, 2018Inventors: Antoine MATHIEU, Benjamin FERAUD, Boris MORELLI, Maxime AMIET
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Publication number: 20180347689Abstract: A speed reducer includes two intermediate lines for a turboprop engine, the reducer including: an input line including an input shaft bearing an input gear wheel, a first intermediate line including a first intermediate shaft bearing a first intermediate gear wheel, a second intermediate line including a second intermediate shaft bearing a second intermediate gear wheel, a spring held by a frame, the spring surrounding a longitudinal portion of the input shaft in order to allow a movement of the input gear wheel towards an equilibrium position corresponding to an equal distribution of the transmission of the power coming from the input shaft to the first intermediate shaft of the first intermediate line and the second intermediate shaft of the second intermediate line.Type: ApplicationFiled: November 30, 2016Publication date: December 6, 2018Inventors: Antoine MATHIEU, Benjamin FERAUD, Boris Pierre Marcel MORELLI
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Patent number: 10047849Abstract: A method for manufacturing a propeller reduction gear, which includes measuring manufacturing defects of the casing; calculating a first angular play induced at each intermediate gear by the measured manufacturing defects; estimating a second angular play induced at each intermediate gear by deformations of the casing when the reduction gear transmits a threshold torque; calculating a total angular play from the first angular play and the second angular play; and selecting two intermediate gears with a phase difference that compensates for the total angular play.Type: GrantFiled: January 12, 2016Date of Patent: August 14, 2018Assignee: SAFRAN TRANSMISSION SYSTEMSInventors: Antoine Mathieu, Benjamin Feraud
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Publication number: 20170363198Abstract: A method for manufacturing a propeller reduction gear, which includes measuring manufacturing defects of the casing; calculating a first angular play induced at each intermediate gear by the measured manufacturing defects; estimating a second angular play induced at each intermediate gear by deformations of the casing when the reduction gear transmits a threshold torque; calculating a total angular play from the first angular play and the second angular play; and selecting two intermediate gears with a phase difference that compensates for the total angular play.Type: ApplicationFiled: January 12, 2016Publication date: December 21, 2017Inventors: Antoine MATHIEU, Benjamin FERAUD
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Publication number: 20170321787Abstract: Speed reduction gear comprising two intermediate transmission lines, in particular for a turbine engine, comprising an input line (12) and an output line that is driven by the input line via said intermediate transmission lines, said intermediate transmission lines being substantially parallel, characterised in that said reduction gear comprises means for distributing loads between said intermediate lines, said load distribution means comprising swiveling coupling means (30) for rotatably coupling one end of the input line, and oil-damping means (40, 50) for damping radial movements of an opposite end of the input line.Type: ApplicationFiled: September 18, 2015Publication date: November 9, 2017Inventors: Benjamin FERAUD, Maxime AMIET, Guillaume BECK, Samuel Raymond Germain BECQUERELLE, Antoine MATHIEU, Boris MORELLI
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Patent number: D953201Type: GrantFiled: June 18, 2020Date of Patent: May 31, 2022Inventors: Olivier Costier, Thierry Sanlaville, Dhylane Nguyen, Maxime Ducloux, Thomas Barse, Antoine Mathieu