Patents by Inventor Antoine Piccirilli

Antoine Piccirilli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8859617
    Abstract: The invention relates to using one or several synthetic or natural furan alkyls for preparing a drug for preventing and/or treating diabetes and insulin resistance, thereby preventing the risks of cardiovascular, nervous, cutaneous, renal, ocular and infectious diseases. The use of one or several synthetic or natural furan alkyls for cosmetically treating diabetes related skin disorders is also disclosed.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: October 14, 2014
    Assignee: Laboratoires Expanscience
    Inventors: Antoine Piccirilli, Philippe Msika, Nathalie Piccardi
  • Publication number: 20140242252
    Abstract: A method for extraction from Lesquerella seeds having an acid value of less than 6 mg KOH/g, said method including the following steps: a seed-processing step i) that includes a single operation of flattening the seeds and at least one operation of drying the seeds; and a step ii) of placing the processed seeds into contact with a mixture of light anhydrous alcohol and co-solvent under temperature and time conditions that are sufficient for extracting a raw oil including phospholipids and gums, as well as obtaining a de-oiled cake.
    Type: Application
    Filed: September 24, 2012
    Publication date: August 28, 2014
    Inventors: Jean-Luc Dubois, Antoine Piccirilli, Julien Magne
  • Patent number: 8816108
    Abstract: The present invention relates to a process for the selective extraction of monoglycerides present in a fraction of fatty acid alkyl esters (FAAEs), comprising at least one stage of liquid-liquid extraction by means of a polar solvent (PS) comprising a light alcohol and optionally of a nonpolar solvent (NS) comprising a solvent which is immiscible with the light alcohol. The present invention relates in particular to a fraction of fatty acid alkyl esters (FAAEs) of vegetable or animal origin, used in particular in biodiesels, capable of being obtained according to the process of the invention, so that its content of monoglycerides is less than 0.6%.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: August 26, 2014
    Assignee: Arkema France
    Inventors: Jean Luc Dubois, Antoine Piccirilli, Julien Magne
  • Patent number: 8759556
    Abstract: The invention relates to a method for the selective extraction of functionalised fatty acid esters from seeds of oleaginous plants, wherein said method includes: a) at least one step of extracting fatty acid esters that comprises simultaneously feeding into a reactor containing said seeds a light anhydrous alcohol, a basic catalyst and an extraction solvent non-miscible with said light alcohol and in which said functionalised fatty ester is not soluble in order to obtain a mixture of esters and glycerol; b) and at least one step of selectively extracting hydroxylated fatty acid esters by feeding into the reactor said extraction solvent in a backflush direction relative to the light alcohol in order to obtain an alcohol phase enriched with fatty acid esters, a glycerol phase and a cake.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: June 24, 2014
    Assignee: Arkema France
    Inventors: Antoine Piccirilli, Jacques Barbier, Julien Magne, Jean-Luc Dubois
  • Patent number: 8747815
    Abstract: The present invention relates to the use of a lupeol-rich extract for the production of a cosmetic or pharmaceutical composition for treating and/or preventing a connective tissue degeneration. Said invention also relates to the use of a lupeol-rich extract for the production of a pharmaceutical composition for preventing and/or treating non-inflammatory articular pathologies, periodontal diseases and stretch marks. The invention also relates to the use of a lupeol-rich extract for the production of a cosmetic composition as a cicatrizing agent, a restructuring agent and an anti-sagging agent for skin and/or mucosae.
    Type: Grant
    Filed: July 19, 2004
    Date of Patent: June 10, 2014
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Antoine Piccirilli, Nathalie Piccardi
  • Patent number: 8734865
    Abstract: The invention relates to a composition comprising a lupin total extract consisting of a lupin sugar extract, comprising at least 50% galactooligosaccharides by weight, in relation to the weight of dry matter, and a lupin peptide extract. The composition can also contain a chromane derivative or a chromene derivative. The invention also relates to a pharmaceutical and/or cosmetic composition comprising said lupin total extract, used advantageously as an anti-inflammatory agent, which repairs the cutaneous barrier and heals, used particularly in the prevention and/or treatment of erythemas.
    Type: Grant
    Filed: April 4, 2005
    Date of Patent: May 27, 2014
    Assignee: Laboratoires Expanscience
    Inventors: Jean-Christophe Choulot, Antoine Piccirilli, Nathalie Piccardi, Philippe Msika, François Paul
  • Patent number: 8735615
    Abstract: A method for extracting an unsaponifiable fraction from a renewable raw material selected among oilfruits, oleaginous seeds, oleoproteaginous seeds, seed husks, oil-yielding almonds, sprouts, stones and cuticles of fruits, high-fat raw materials from animals, algae, fungus or yeast, includes the following steps: a) dehydrating and packaging the renewable raw material, not resulting in any extraction of the fat; b) reactive crushing of the fatty packaged raw material in the presence of a light alcohol and a catalyst; c) evaporating the light alcohol; d) concentrating the liquid phase such as to obtain a concentrate including the unsaponifiable fraction diluted in fatty acid alkyl esters; e) saponifying the unsaponifiable concentrate; f) extracting the unsaponifiable fraction from the saponified mixture. The use of an unsaponifiable fraction or co-products obtained by implementing the method for preparing a composition such as a cosmetic, drug, food, or food additive or supplement is also described.
    Type: Grant
    Filed: October 21, 2010
    Date of Patent: May 27, 2014
    Assignee: Valagro Carbone Renouvelable Poitou-Charentes
    Inventor: Antoine Piccirilli
  • Publication number: 20140096577
    Abstract: A process including at least one reactive trituration step which includes putting an oil cake including from 3% to 30% oil in contact with an anhydrous light alcohol and an alkaline catalyst under temperature and time conditions that are sufficient to allow for the extraction and transesterification of the vegetable oil and lead to the production of a mixture including fatty acid esters and glycerol, and a de-oiled cake including less than 3% oil. Also, a detoxified de-oiled cake as well as to a mixture of fatty acid esters with improved stability and resistance to oxidation.
    Type: Application
    Filed: May 23, 2012
    Publication date: April 10, 2014
    Applicant: ARKEMA FRANCE
    Inventors: Jean-Luc Dubois, Antoine Piccirilli
  • Patent number: 8653117
    Abstract: The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: February 18, 2014
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Nathalie Piccardi, Antoine Piccirilli
  • Publication number: 20130211115
    Abstract: The present invention relates to a process for the selective extraction of monoglycerides present in a fraction of fatty acid alkyl esters (FAAEs), comprising at least one stage of liquid-liquid extraction by means of a polar solvent (PS) comprising a light alcohol and optionally of a nonpolar solvent (NS) comprising a solvent which is immiscible with the light alcohol. The present invention relates in particular to a fraction of fatty acid alkyl esters (FAAEs) of vegetable or animal origin, used in particular in biodiesels, capable of being obtained according to the process of the invention, so that its content of monoglycerides is less than 0.6%.
    Type: Application
    Filed: June 24, 2011
    Publication date: August 15, 2013
    Applicant: ARKEMA FRANCE
    Inventors: Jean Luc Dubois, Antoine Piccirilli, Julien Magne
  • Publication number: 20130052328
    Abstract: The present invention relates to a method for reactively crushing jatropha seeds, said method making it possible, starting with specifically conditioned jatropha seeds in the presence of light alcohol and a basic catalyst, to carry out, in a single step, the crushing as well as the reaction for transesterifying the triglycerides present in the jatropha oil, thus causing an oil cake, glycerol, and fatty acid esters to be simultaneously produced. The method for processing the jatropha seeds, according to the invention, makes it possible to inactivate, in a simple, low-cost manner, the phorbol esters in addition to the curcine, thus enabling humans to handle the seeds without risk and moreover use the castor oil cake in animal feed. Characteristically, the seeds are conditioned by a series of operations that include a step of pressing the seeds and a step of drying same.
    Type: Application
    Filed: January 26, 2011
    Publication date: February 28, 2013
    Inventors: Jean-Luc Dubois, Julien Magne, Antoine Piccirilli
  • Patent number: 8349377
    Abstract: The invention relates to a medicament which comprises a peptide extract of avocado and which can also comprise a composition containing D-mannoheptulose and/or perseitol, such as a water-soluble extract of avocado sugars, and/or a peptide extract of lupine. The inventive medicament is intended for the treatment and/or prevention of illnesses that are linked to an alteration in innate and/or acquired immunity, through an increase in the production of anti-microbial peptides, preferably hBD-2, without inducing inflammatory reactions, irritations or intolerances.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: January 8, 2013
    Assignee: Laboratoires Expanscience
    Inventors: Antoine Piccirilli, Nathalie Piccardi, Philippe Msika, François Paul, Stéphanie Bredif
  • Patent number: 8318186
    Abstract: The invention concerns the use of at least a fatty ester for preparing a composition designed to inhibit 5?-reductase activity. Said use produces a remarkable inhibiting effect of 5?-reductase thereby providing a novel response for treating dermatological pathologies and/or disorders related to congenital or acquired exaggeration of 5?-reductase activity, in particular for treating prostatic hypertrophy, prostatic adenoma, acne, hyperseborrhea, alopecia and hirsutism. The invention also concerns cosmetic treatment methods, in particular for greasy skin, and the use of said fatty esters as additives in a food product for human and/or animal consumption.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: November 27, 2012
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Antoine Piccirilli, Jacques Legrand
  • Patent number: 8304453
    Abstract: The invention concerns a composition containing at least an alkanolamide, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an oxazolin, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular its use for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such a composition on the skin and/or mucosa.
    Type: Grant
    Filed: April 27, 2006
    Date of Patent: November 6, 2012
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Nathalie Piccardi, Antoine Piccirilli
  • Publication number: 20120219709
    Abstract: Disclosed is a method of using at least one functionalized hydroxycarboxylic acid oligomer as an adhesive for bonding materials. Also described is a process for manufacturing functionalized hydroxycarboxylic acid oligomers including at least one stage for polycondensation of a hydroxycarboxylic acid and a functional agent, as well as functionalized hydroxycarboxylic acid oligomers that can be obtained and the adhesive compositions that include them.
    Type: Application
    Filed: October 27, 2010
    Publication date: August 30, 2012
    Applicant: VALAGRO CARBONE RENOUVELABLE POITOU-CHARENTES
    Inventors: Antoine Piccirilli, Cedric Dever
  • Publication number: 20120209018
    Abstract: A method for extracting an unsaponifiable fraction from a renewable raw material selected among oilfruits, oleaginous seeds, oleoproteaginous seeds, seed husks, oil-yielding almonds, sprouts, stones and cuticles of fruits, high-fat raw materials from animals, algae, fungus or yeast, includes the following steps: a) dehydrating and packaging the renewable raw material, not resulting in any extraction of the fat; b) reactive crushing of the fatty packaged raw material in the presence of a light alcohol and a catalyst; c) evaporating the light alcohol; d) concentrating the liquid phase such as to obtain a concentrate including the unsaponifiable fraction diluted in fatty acid alkyl esters; e) saponifying the unsaponifiable concentrate; f) extracting the unsaponifiable fraction from the saponified mixture. The use of an unsaponifiable fraction or co-products obtained by implementing the method for preparing a composition such as a cosmetic, drug, food, or food additive or supplement is also described.
    Type: Application
    Filed: October 21, 2010
    Publication date: August 16, 2012
    Applicant: VALAGRO CARBONE RENOUVELABLE POITOU-CHARENTES
    Inventor: Antoine Piccirilli
  • Patent number: 8236836
    Abstract: The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: August 7, 2012
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Nathalie Piccardi, Antoine Piccirilli
  • Patent number: 8147883
    Abstract: The invention concerns the use of at least a vegetable oil product selected among the group consisting of vegetable oil oleic distillates, vegetable oil unsaponifiable matters, vegetable oil furan lipids and mixtures thereof, as agents for increasing skin lipid synthesis, in particular lipids of the epidermal skin barrier, in or for preparing a composition containing a pharmaceutically or dermatologically acceptable medium. The use enables to prevent and/or treat deterioration of the skin barrier (dry skin, skin subjected to actinic radiation, ichthyosis, acne, xerosis, atopic dermatitis, sensitive skin, chafing and reactive skin, itching and the like).
    Type: Grant
    Filed: September 20, 2000
    Date of Patent: April 3, 2012
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Antoine Piccirilli
  • Publication number: 20120077999
    Abstract: The invention relates to a method for the selective extraction of functionalised fatty acid esters from seeds of oleaginous plants, wherein said method includes: a) at least one step of extracting fatty acid esters that comprises simultaneously feeding into a reactor containing said seeds a light anhydrous alcohol, a basic catalyst and an extraction solvent non-miscible with said light alcohol and in which said functionalised fatty ester is not soluble in order to obtain a mixture of esters and glycerol; b) and at least one step of selectively extracting hydroxylated fatty acid esters by feeding into the reactor said extraction solvent in a backflush direction relative to the light alcohol in order to obtain an alcohol phase enriched with fatty acid esters, a glycerol phase and a cake.
    Type: Application
    Filed: January 13, 2010
    Publication date: March 29, 2012
    Applicant: Arkema France
    Inventors: Antoine Piccirilli, Jacques Barbier, Julien Magne, Jean-Luc Dubois
  • Publication number: 20110281941
    Abstract: The present invention relates to the cosmetic use, by the oral route, of a combination of lycopene, of vitamin C, of vitamin E and of at least one polyphenol compound derived from pine bark as active ingredient intended for maintaining and/or restoring the biomechanical properties of keratinous materials, and notably of the skin.
    Type: Application
    Filed: December 3, 2009
    Publication date: November 17, 2011
    Applicant: LABORATOIRES INNEOV SNC
    Inventors: Patricia Manissier, Christiane Montastier, Antoine Piccirilli