Patents by Inventor Antoine Tesniere

Antoine Tesniere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF P2X7 PATHWAY FOR ASSESSING THE SENSITIVITY OF A SUBJECT TO A CANCER TREATMENT
    Publication number: 20110229411
    Abstract: The present invention concerns methods for assessing the sensibility of a subject to an anticancer treatment, for screening compounds which are useful for treating a cancer and for determining the likelihood of a metastatic relapse in a subject. The methods are based on the finding that a non-functional P2X7-elicited NALP3 inflammasome pathway in a subject is indicative of a resistance to treatment. The invention further concerns methods for treating a cancer and for restoring the sensitivity of the subject to a cancer treatment.
    Type: Application
    Filed: November 27, 2008
    Publication date: September 22, 2011
    Applicants: INSTITUT GUSTAVE ROUSSY, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), UNIVERSITE PARIS-SUD XI
    Inventors: Lionel Apetoh, Antoine Tesniere, François Ghiringhelli, Laurence Zitvogel, Guido Kroemer