Patents by Inventor Anton Blencowe
Anton Blencowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10758626Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.Type: GrantFiled: September 9, 2016Date of Patent: September 1, 2020Assignee: POLYACTIVA PTY LTDInventors: Stephen Lonsdale Birkett, Andrew Craig Donohue, Asha Marina D'Souza, Sarah Man Yee Ng, Adrian Sulistio, Russell John Tait, David Valade, Alan Naylor, Anton Blencowe
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Publication number: 20200024403Abstract: The present disclosure relates to injectable compositions and methods of making injectable compositions of moisture curing siloxane polymers for forming accommodating intraocular lenses. In certain embodiments, the moisture curing siloxane polymers are comprised of an organosilicon compound and a hydrolytically sensitive siloxane moiety and have a specific gravity of greater than about 0.95, a number average molecular weight (Mn) greater than about 5,000 or about 20,000 and a weight average molecular weight (Mw) greater than about 20,000 or about 40,000. The disclosure includes accommodating intraocular lenses formed from moisture curing siloxane polymers and having a modulus of elasticity of less than about 6 kPa, less than 20% post-cure extractables, refractive index ranging from 1.4 to 1.5 and dioptric range of accommodation of 0D to 10D.Type: ApplicationFiled: June 4, 2019Publication date: January 23, 2020Inventors: Jason Watling, Stephen Clarke, Kim-Anh Thi Nguyen, Tony Aitchison, Elda Markovic, Anton Blencowe, Chun Kit Lo
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Patent number: 10351675Abstract: The present disclosure relates to injectable compositions and methods of making injectable compositions of moisture curing siloxane polymers for forming accommodating intraocular lenses. In certain embodiments, the moisture curing siloxane polymers are comprised of an organosilicon compound and a hydrolytically sensitive siloxane moiety and have a specific gravity of greater than about 0.95, a number average molecular weight (Mn) greater than about 5,000 or about 20,000 and a weight average molecular weight (Mw) greater than about 20,000 or about 40,000. The disclosure includes accommodating intraocular lenses formed from moisture curing siloxane polymers and having a modulus of elasticity of less than about 6 kPa, less than 20% post-cure extractables, refractive index ranging from 1.4 to 1.5 and dioptric range of accommodation of 0D to 10D.Type: GrantFiled: December 21, 2015Date of Patent: July 16, 2019Assignee: Adventus Technology, Inc.Inventors: Jason Watling, Stephen Clarke, Kim-Anh Thi Nguyen, Tony Aitchison, Elda Markovic, Anton Blencowe, Chun Kit Lo
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Publication number: 20190194389Abstract: Biodegradable polyether network polymers crosslinked via ester linkages, to substrates, implants and scaffolds including the biodegradable polyether network polymers; methods for preparing such network polymers, implants and scaffolds; and methods of using substrates, implants and scaffolds including the network polymers, particularly for culturing cells and regenerating tissue.Type: ApplicationFiled: November 29, 2018Publication date: June 27, 2019Inventors: Anton Blencowe, Berkay Ozcelik, Greg Guanghua Qiao
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Patent number: 10179834Abstract: The disclosure relates to biodegradable polyether network polymers crosslinked via ester linkages, to substrates, implants and scaffolds comprising the biodegradable polyether network polymers, to methods for preparing such network polymers, implants and scaffolds, and to methods of using substrates, implants and scaffolds comprising the network polymers, particularly for culturing cells and regenerating tissue.Type: GrantFiled: April 10, 2014Date of Patent: January 15, 2019Assignee: The University of MelbourneInventors: Anton Blencowe, Berkay Ozcelik, Greg Guanghua Qiao
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Patent number: 10111886Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, .beta.-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.Type: GrantFiled: February 17, 2017Date of Patent: October 30, 2018Assignee: POLYACTIVA PTY LTDInventors: Sarah Man Yee Ng, Andrew Craig Donohue, Russell John Tait, Stephen Lonsdale Birkett, Adrian Sulistio, Anton Blencowe
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Patent number: 10113033Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety comprising prostaglandin analogues. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.Type: GrantFiled: March 14, 2017Date of Patent: October 30, 2018Assignee: POLYACTIVA PTY LTDInventors: Sarah Man Yee Ng, Andrew Craig Donohue, Russell John Tait, Stephen Lonsdale Birkett, Adrian Sulistio, Anton Blencowe, Alan Naylor
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Publication number: 20180273687Abstract: The present disclosure relates to injectable compositions and methods of making injectable compositions of moisture curing siloxane polymers for forming accommodating intraocular lenses. In certain embodiments, the moisture curing siloxane polymers are comprised of an organosilicon compound and a hydrolytically sensitive siloxane moiety and have a specific gravity of greater than about 0.95, a number average molecular weight (Mn) greater than about 5,000 or about 20,000 and a weight average molecular weight (Mw) greater than about 20,000 or about 40,000. The disclosure includes accommodating intraocular lenses formed from moisture curing siloxane polymers and having a modulus of elasticity of less than about 6 kPa, less than 20% post-cure extractables, refractive index ranging from 1.4 to 1.5 and dioptric range of accommodation of OD to 10D.Type: ApplicationFiled: December 21, 2015Publication date: September 27, 2018Inventors: Jason Watling, Stephen Clarke, Kim-Anh Thi Nguyen, Tony Aitchison, Elda Markovic, Anton Blencowe, Chun Kit Lo
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Publication number: 20170216308Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, .beta.-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.Type: ApplicationFiled: February 17, 2017Publication date: August 3, 2017Applicant: POLYACTIVA PTY LTDInventors: Sarah Man Yee Ng, Andrew Craig DONOHUE, Russell John TAIT, Stephen Lonsdale BIRKETT, Adrian SULISTIO, Anton BLENCOWE
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Publication number: 20170182173Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety comprising prostaglandin analogues. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.Type: ApplicationFiled: March 14, 2017Publication date: June 29, 2017Applicant: POLYACTIVA PTY LTDInventors: Sarah Man Yee Ng, Andrew Craig DONOHUE, Russell John TAIT, Stephen Lonsdale BIRKETT, Adrian SULISTIO, Anton BLENCOWE, Alan Naylor
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Patent number: 9572892Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogs, ?-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.Type: GrantFiled: March 7, 2014Date of Patent: February 21, 2017Assignee: POLYACTIVA PTY LTDInventors: Sarah Man Yee Ng, Andrew Craig Donohue, Russell John Tait, Stephen Lonsdale Birkett, Adrian Sulistio, Anton Blencowe
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Publication number: 20160060392Abstract: The disclosure relates to biodegradable polyether network polymers crosslinked via ester linkages, to substrates, implants and scaffolds comprising the biodegradable polyether network polymers, to methods for preparing such network polymers, implants and scaffolds, and to methods of using substrates, implants and scaffolds comprising the network polymers, particularly for culturing cells and regenerating tissue.Type: ApplicationFiled: April 10, 2014Publication date: March 3, 2016Inventors: Anton BLENCOWE, Berkay OZCELIK, Greg Guanghua QIAO
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Publication number: 20160000929Abstract: The presentinvention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, ?-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.Type: ApplicationFiled: March 7, 2014Publication date: January 7, 2016Applicant: POLYACTIVA PTY LTDInventors: Sarah Man Yee NG, Andrew Craig DONOHUE, Russell John TAIT, Stephen Lonsdale BIRKETT, Adrian SULISTIO, Anton BLENCOWE
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Patent number: 8696987Abstract: The present invention relates to a method for controlling evaporation from a body of water. The method of the invention uses a water insoluble compound and a water soluble polymer, which interact with each other by non-covalent bonding interactions.Type: GrantFiled: December 22, 2009Date of Patent: April 15, 2014Assignee: Polymers CRC LtdInventors: David Henry Solomon, Emma Louise Prime, Devi Sunartio, Greg Guanghua Qiao, Ian Dagley, Anton Blencowe
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Publication number: 20120018387Abstract: The present invention relates to a method for controlling evaporation from a body of water. The method of the invention uses a water insoluble compound and a water soluble polymer, which interact with each other by non-covalent bonding interactions.Type: ApplicationFiled: December 22, 2009Publication date: January 26, 2012Applicant: POLYMERS CRC LTDInventors: David Henry Solomon, Emma Louise Prime, Devi Sunartio, Greg Guanghua Qiao, Ian Dagley, Anton Blencowe