Abstract: The present disclosure provides nanoparticles comprising a polymer and a plurality of TLR agonist moieties conjugated to the polymer and present on the surface of the nanoparticles. Methods of producing the nanoparticles, hydrogels comprising the nanoparticles, and vaccines comprising the nanoparticles and/or hydrogels are also provided. Methods for inducing an antigen-specific humoral immune response or enhancing cancer immunotherapy in a subject are also provided.

Abstract: Provided herein are compositions including lipids and copolymers in the form of a nanodisc assembly. The subject copolymers include monomer units of styrene and monomer units selected from acrylic acid and an acrylic acid derivative. In certain cases, the copolymer is a copolymer of styrene and acrylic acid. Also provided herein, is an aqueous solution comprising the subject composition. Also provided herein, are methods for producing a nanodisc assembly, including incubation of a lipid and a subject copolymer. Further provided herein, are methods for solubilizing a membrane protein in an aqueous solution, wherein the method includes forming a nanodisc assembly of a lipid bilayer having one or more membrane proteins embedded therein, and a subject copolymer. Also provided are methods of solubilizing a hydrophobic constituent in an aqueous solution, including forming a nanodisc assembly of a lipid, a hydrophobic constituent, and a subject copolymer.

Abstract: A method and apparatus is described in which a series of short-circuiting pulses is applied to a motor. A current in the motor is determined after one or more of the series of short circuit pulses has completed. The duration of the short-circuit pulses is adjusted depending on the determined current. The method and apparatus may be used within an arrangement for catching a spinning motor.

Abstract: A method (100) is disclosed, the method being performed in a network controller of a Mobile Transport Network. The Mobile Transport Network comprises communication links interconnecting network entities of a cellular Radio Access Network (RAN) and a core network. The method comprises receiving, from a network entity in the core network, an indication of traffic load within the RAN or between the RAN and the core network (102). Also disclosed is a method (200), performed in a network entity of a core network, the core network being connected to a cellular RAN by a Mobile Transport Network. The Mobile Transport Network comprises communication links interconnecting network entities of the core network and the RAN. The method (200) comprises sending to a network controller of the Mobile Transport Network an indication of traffic load within the RAN or between the RAN and the core network (202).

Abstract: A method and apparatus for catching a rotating motor is described. Switches (typically the lower switches) of an inverter of a motor drive circuit are short-circuited for a brief period of time. The pulses generated by this process are analyzed to determine the speed and direction of rotation of the motor. The pulses are checked to determine whether they are orthogonal. If they are, the motor velocity determination is deemed to be reliable and then motor is magnetized and normal motor control can be resumed. If not, the motor velocity determination is deemed to be unreliable and a magnetization pulse before the velocity determination step is repeated.

Abstract: A method and apparatus is described in which a series of short-circuiting pulses is applied to a motor. A current in the motor is determined after one or more of the series of short circuit pulses has completed. The duration of the short-circuit pulses is adjusted depending on the determined current. The method and apparatus may be used within an arrangement for catching a spinning motor.

Abstract: A compound is provided, which comprise an anionic polymer carrier conjugated to an antiviral drug via a biodegradable linker. This compound is particularly useful as a broad-spectrum antiviral agent.

Abstract: A method and apparatus for catching a rotating motor is described. Switches (typically the lower switches) of an inverter of a motor drive circuit are short-circuited for a brief period of time. The pulses generated by this process are analysed to determine the speed and direction of rotation of the motor. The pulses are checked to determine whether they are orthogonal. If they are, the motor velocity determination is deemed to be reliable and then motor is magnetised and normal motor control can be resumed. If not, the motor velocity determination is deemed to be unreliable and a magnetization pulse before the velocity determination step is repeated.

Abstract: A method (100) is disclosed, the method being performed in a network controller of a Mobile Transport Network. The Mobile Transport Network comprises communication links interconnecting network entities of a cellular Radio Access Network (RAN) and a core network. The method comprises receiving, from a network entity in the core network, an indication of traffic load within the RAN or between the RAN and the core network (102). Also disclosed is a method (200), performed in a network entity of a core network, the core network being connected to a cellular RAN by a Mobile Transport Network. The Mobile Transport Network comprises communication links interconnecting network entities of the core network and the RAN. The method (200) comprises sending to a network controller of the Mobile Transport Network an indication of traffic load within the RAN or between the RAN and the core network (202).

Abstract: This invention relates to a composition of a unique combination of three novel dietary supplements for use in a weight loss program. The composition includes a mood enhancer, an insulin sparing agent, and a peripheral energy blocker. Also provided is a method of treatment in a weight loss program.

Abstract: This invention relates to a dietary supplement for use in a weight loss program, which alleviates insulin resistance in the presence of the metabolic syndrome. The dietary supplement includes, in combination, berberine, banaba leaf extract, and inositol. Also provided is a method of treatment in a weight loss program.

Abstract: This invention relates to a composition of a unique combination of three novel dietary supplements for use in a weight loss program. The composition includes a mood enhancer, an insulin sparing agent, and a peripheral energy blocker. Also provided is a method of treatment in a weight loss program.

Abstract: This invention relates to a dietary supplement for use in a weight loss program, which alleviates insulin resistance in the presence of the metabolic syndrome. The dietary supplement includes, in combination, berberine, banaba leaf extract, and inositol. Also provided is a method of treatment in a weight loss program.

Abstract: According to the present invention a building element comprises a generally planar panel defining at least one substantially straight side end and a first connecting lug extending co-planarly to the panel from the substantially straight side end. The first connecting lug extends along only a portion of said straight side end, and a slot is provided in the form of an elongate aperture extending partly into the first connecting lug or partly into the panel adjacent to the first connecting lug. The slot extends adjacent to the straight side end and parallel thereto, and the slot is open at one end thereof. The arrangement is such that two building elements with slots being open at opposite ends can be attached to each other by positioning the panels at right angles to each other and sliding the slots over each other in a direction along the straight side ends in order that the slots engage the elements. The invention also relates to structures formed by using the above elements.