Patents by Inventor Antonella Bartoloni

Antonella Bartoloni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
    Patent number: 7410646
    Abstract: Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: August 12, 2008
    Assignee: Novartis Vaccines and Diagnostics S.R.L.
    Inventors: Mariagrazia Pizza, Antonella Bartoloni, Rino Rappuoli
  • Immunologically active peptides with altered toxicity useful for the preparation of antipertussis vaccine
    Publication number: 20050281837
    Abstract: Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganisms transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.
    Type: Application
    Filed: January 29, 2004
    Publication date: December 22, 2005
    Applicant: Chiron S.r.l.
    Inventors: Mariagrazia Pizza, Antonella Bartoloni, Rino Rappuoli
  • Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
    Patent number: 6713072
    Abstract: Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating, a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: March 30, 2004
    Assignee: Chiron S.r.l.
    Inventors: Mariagrazia Pizza, Antonella Bartoloni, Rino Rappuoli
  • Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
    Patent number: 5925546
    Abstract: Immunological active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 20, 1999
    Assignee: Chiron S.p.A.
    Inventors: Mariagrazia Pizza, Antonella Bartoloni, Rino Rappuoli
  • DNA sequences for immunologically active peptides of pertussis toxin
    Patent number: 5889172
    Abstract: Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 30, 1999
    Assignee: Chiron S.p.A.
    Inventors: Mariagrazia Pizza, Antonella Bartoloni, Rino Rappuoli