Abstract: The present invention provides a phosphoramidate compound having the structure (I) wherein X comprises a monosaccharide group comprising the structure (II) or (III) or a pharmaceutically acceptable salt, ester or salt of such ester. The present invention also provides processes for the production of (I) and uses thereof.

Abstract: The present invention provides a phosphoramidate compound comprising the structure (I) Formula (I) wherein: X comprises a monosaccharide group comprising the structure (II) or (III), 8 Formula (II), (III) B and B are independently selected from the group consisting of —O—, —CH2— and a bond, preferably —O—; R1 is selected from the group consisting of —H, protecting groups and monovalent hydrocarbon radicals; R2 and R3 are independently selected from the group consisting of —H and monovalent hydrocarbon radicals, or R2 and R3 together form an alkylene or heteroalkylene chain so as to provide, together with the C atom to which they are attached, a cyclic system; R4 is selected from the group consisting of —H and monovalent hydrocarbon radicals; R5-R12 are independently selected from the group consisting of —H, —OH, N3, halogen, —SH, —OR13, —SR13?, NHR14, —NR142 and group Formula (I) wherein B? is selected from the group consisting of —O—, —CH2— and a bond, preferably —O—; R1-R4 are independently selected and are