Patents by Inventor Antonella GUZZONATO

Antonella GUZZONATO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250069876
    Abstract: A method of operating a sample introduction system of an inductively coupled plasma analytical instrument, the method comprising applying a trained classifier to instrument data, obtained from the analytical instrument, during operation of the analytical instrument, to detect whether the sample introduction system is operating in a normal state or in a failure state. The method further comprises activating an error procedure in the event that the sample introduction system is operating in a failure state. The instrument data comprises signal data obtained from an analytical measurement made by the analytical instrument. The trained classifier is trained using a training data set comprising instrument data corresponding to the normal state of the sample introduction system.
    Type: Application
    Filed: December 20, 2022
    Publication date: February 27, 2025
    Applicant: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Antonella Guzzonato, Mischa Jahn
  • Publication number: 20250052615
    Abstract: A peak position measurement offset is determined in a two-dimensional optical spectrum. A plurality of peaks are identified that appear in both a spectrum obtained from a reference material at known conditions and a spectrum obtained from a sample of interest. The peak position measurement offset is determined by a comparison of a pattern formed by peak positions of the plurality of identified peaks in the spectrum obtained from the sample of interest against the plurality of identified peaks in the spectrum obtained from the reference material.
    Type: Application
    Filed: December 12, 2022
    Publication date: February 13, 2025
    Applicants: Thermo Fisher Scientific (Shanghai) Instruments Co., Ltd., Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Shenghai Wu, Antonella Guzzonato, Cheng Wang
  • Publication number: 20250044153
    Abstract: A method of operating a spectrometer controller is provided. The method comprises obtaining an interfered peak using a detector of a spectrometer, wherein the interfered peak is produced by a plurality of spectral emissions of different wavelengths, each of the plurality of spectral emissions in the interfered peak incident on the detector at an associated detector location. For one or more of the spectral emissions of the interfered peak, an associated curve is generated using a neural network, wherein the neural network is trained to output data indicative of a shape of the associated curve based on data representative of the associated detector location. For one or more of the spectral emissions of the interfered peak, the associated curve is output.
    Type: Application
    Filed: December 14, 2022
    Publication date: February 6, 2025
    Applicant: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Antonella Guzzonato, Ningning Pan, Mischa Jahn
  • Publication number: 20250035486
    Abstract: Disclosed herein are spectrometer support systems, as well as related methods, computing devices, and computer-readable media. For example, in some embodiments, a spectrometer support apparatus may: receive, for each of a plurality of calibration samples of an analyte at different known concentrations, an array of spectrometer output intensities of the calibration sample, wherein different ones of the spectrometer output intensities in the array are associated with data representative of different deflection amounts; train a machine-learning computational model, using the plurality of known concentrations of the analyte in the calibration samples and the associated plurality of arrays of spectrometer output intensities, to output a concentration of the analyte in a target sample based on an input array of spectrometer output intensities of the target sample; and use the trained machine-learning computational model as a calibration model for the analyte for subsequent spectrometer operation.
    Type: Application
    Filed: December 9, 2022
    Publication date: January 30, 2025
    Inventors: Antonella Guzzonato, Isabel Fernanda Huebener
  • Patent number: 12163837
    Abstract: A method of determining a peak intensity in an optical spectrum is described. The method includes producing a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array. An offset using an actual location and an expected location of a peak of an interpolated subarray is used to adjust an expected location of another peak that is within another two-dimensional subarray. Interpolated spectrum values are then used to produce a peak intensity value of the second peak.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: December 10, 2024
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Hans-Juergen Schlueter, Antonella Guzzonato, Norbert Quaas, Peter Huelstede
  • Publication number: 20240044707
    Abstract: A method of optical spectroscopy for analysing a sample using an optical spectrometer is provided. The method comprises obtaining a sample spectrum of the sample using the optical spectrometer and obtaining a blank spectrum using the optical spectrometer. The blank spectrum comprises structured background radiation which is correlated with the sample spectrum. A cross-correlation of the sample spectrum and the blank spectrum is determined. A mapped blank spectrum is generated by mapping the blank spectrum to the sample spectrum based on the cross-correlation, and the mapped blank spectrum is subtracted from the sample spectrum to generate a background corrected sample spectrum.
    Type: Application
    Filed: December 16, 2021
    Publication date: February 8, 2024
    Applicant: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Lutz Frommberger, Hans-Jurgen Schluter, Konstantin Ayzikov, Antonella Guzzonato
  • Publication number: 20220252454
    Abstract: A method of determining a peak intensity in an optical spectrum is described. The method includes producing a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array. An offset using an actual location and an expected location of a peak of an interpolated subarray is used to adjust an expected location of another peak that is within another two-dimensional subarray. Interpolated spectrum values are then used to produce a peak intensity value of the second peak.
    Type: Application
    Filed: July 30, 2020
    Publication date: August 11, 2022
    Inventors: Hans-Juergen Schlueter, Antonella Guzzonato, Norbert Quaas, Peter Huelstede
  • Publication number: 20220178890
    Abstract: Described are techniques for performing automated maintenance evaluations on a gas chromatograph (GC) or a gas chromatograph-mass spectrometer (GC-MS). Systems and methods are described for directing an injector of a GC or GC-MS instrument system to autonomously inject a diagnostic material sample into a material analysis chamber and initiate a scientific analysis to formulate a set of results. The systems and methods further include the instrument system analyzing the set of results generating one or more output reports.
    Type: Application
    Filed: December 8, 2020
    Publication date: June 9, 2022
    Inventors: Deven L. SHINHOLT, Edward B. McCAULEY, Riccardo FACCHETTI, Antonella GUZZONATO
  • Publication number: 20200378929
    Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.
    Type: Application
    Filed: August 17, 2020
    Publication date: December 3, 2020
    Inventors: Antonella GUZZONATO, Heinz MEHLMANN, Hans-Juergen SCHLUETER
  • Patent number: 10761069
    Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: September 1, 2020
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Antonella Guzzonato, Heinz Mehlmann, Hans-Juergen Schlueter
  • Patent number: 10656130
    Abstract: An elemental analysis system includes a reactor having at least one reduction reaction zone including a metal zeolite that can reduce nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reduction. Correspondingly, a method of elemental analysis includes providing a reactor having at least one reduction reaction zone including a metal zeolite and reducing nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reaction on the metal zeolite.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: May 19, 2020
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Antonella Guzzonato, Christopher Brodie
  • Publication number: 20190346410
    Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.
    Type: Application
    Filed: July 29, 2019
    Publication date: November 14, 2019
    Inventors: Antonella GUZZONATO, Heinz MEHLMANN, Hans-Juergen SCHLUETER
  • Patent number: 10365256
    Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: July 30, 2019
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Antonella Guzzonato, Heinz Mehlmann, Hans-Juergen Schlueter
  • Publication number: 20170336374
    Abstract: An elemental analysis system includes a reactor having at least one reduction reaction zone including a metal zeolite that can reduce nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reduction. Correspondingly, a method of elemental analysis includes providing a reactor having at least one reduction reaction zone including a metal zeolite and reducing nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reaction on the metal zeolite.
    Type: Application
    Filed: May 1, 2017
    Publication date: November 23, 2017
    Inventors: Antonella GUZZONATO, Christoper BRODIE
  • Publication number: 20170184552
    Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.
    Type: Application
    Filed: December 16, 2016
    Publication date: June 29, 2017
    Inventors: Antonella GUZZONATO, Heinz MEHLMANN, Hans-Juergen SCHLUETER