Patents by Inventor Antonella GUZZONATO
Antonella GUZZONATO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250069876Abstract: A method of operating a sample introduction system of an inductively coupled plasma analytical instrument, the method comprising applying a trained classifier to instrument data, obtained from the analytical instrument, during operation of the analytical instrument, to detect whether the sample introduction system is operating in a normal state or in a failure state. The method further comprises activating an error procedure in the event that the sample introduction system is operating in a failure state. The instrument data comprises signal data obtained from an analytical measurement made by the analytical instrument. The trained classifier is trained using a training data set comprising instrument data corresponding to the normal state of the sample introduction system.Type: ApplicationFiled: December 20, 2022Publication date: February 27, 2025Applicant: Thermo Fisher Scientific (Bremen) GmbHInventors: Antonella Guzzonato, Mischa Jahn
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Publication number: 20250052615Abstract: A peak position measurement offset is determined in a two-dimensional optical spectrum. A plurality of peaks are identified that appear in both a spectrum obtained from a reference material at known conditions and a spectrum obtained from a sample of interest. The peak position measurement offset is determined by a comparison of a pattern formed by peak positions of the plurality of identified peaks in the spectrum obtained from the sample of interest against the plurality of identified peaks in the spectrum obtained from the reference material.Type: ApplicationFiled: December 12, 2022Publication date: February 13, 2025Applicants: Thermo Fisher Scientific (Shanghai) Instruments Co., Ltd., Thermo Fisher Scientific (Bremen) GmbHInventors: Shenghai Wu, Antonella Guzzonato, Cheng Wang
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Publication number: 20250044153Abstract: A method of operating a spectrometer controller is provided. The method comprises obtaining an interfered peak using a detector of a spectrometer, wherein the interfered peak is produced by a plurality of spectral emissions of different wavelengths, each of the plurality of spectral emissions in the interfered peak incident on the detector at an associated detector location. For one or more of the spectral emissions of the interfered peak, an associated curve is generated using a neural network, wherein the neural network is trained to output data indicative of a shape of the associated curve based on data representative of the associated detector location. For one or more of the spectral emissions of the interfered peak, the associated curve is output.Type: ApplicationFiled: December 14, 2022Publication date: February 6, 2025Applicant: Thermo Fisher Scientific (Bremen) GmbHInventors: Antonella Guzzonato, Ningning Pan, Mischa Jahn
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Publication number: 20250035486Abstract: Disclosed herein are spectrometer support systems, as well as related methods, computing devices, and computer-readable media. For example, in some embodiments, a spectrometer support apparatus may: receive, for each of a plurality of calibration samples of an analyte at different known concentrations, an array of spectrometer output intensities of the calibration sample, wherein different ones of the spectrometer output intensities in the array are associated with data representative of different deflection amounts; train a machine-learning computational model, using the plurality of known concentrations of the analyte in the calibration samples and the associated plurality of arrays of spectrometer output intensities, to output a concentration of the analyte in a target sample based on an input array of spectrometer output intensities of the target sample; and use the trained machine-learning computational model as a calibration model for the analyte for subsequent spectrometer operation.Type: ApplicationFiled: December 9, 2022Publication date: January 30, 2025Inventors: Antonella Guzzonato, Isabel Fernanda Huebener
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Patent number: 12163837Abstract: A method of determining a peak intensity in an optical spectrum is described. The method includes producing a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array. An offset using an actual location and an expected location of a peak of an interpolated subarray is used to adjust an expected location of another peak that is within another two-dimensional subarray. Interpolated spectrum values are then used to produce a peak intensity value of the second peak.Type: GrantFiled: July 30, 2020Date of Patent: December 10, 2024Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Hans-Juergen Schlueter, Antonella Guzzonato, Norbert Quaas, Peter Huelstede
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Publication number: 20240044707Abstract: A method of optical spectroscopy for analysing a sample using an optical spectrometer is provided. The method comprises obtaining a sample spectrum of the sample using the optical spectrometer and obtaining a blank spectrum using the optical spectrometer. The blank spectrum comprises structured background radiation which is correlated with the sample spectrum. A cross-correlation of the sample spectrum and the blank spectrum is determined. A mapped blank spectrum is generated by mapping the blank spectrum to the sample spectrum based on the cross-correlation, and the mapped blank spectrum is subtracted from the sample spectrum to generate a background corrected sample spectrum.Type: ApplicationFiled: December 16, 2021Publication date: February 8, 2024Applicant: Thermo Fisher Scientific (Bremen) GmbHInventors: Lutz Frommberger, Hans-Jurgen Schluter, Konstantin Ayzikov, Antonella Guzzonato
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Publication number: 20220252454Abstract: A method of determining a peak intensity in an optical spectrum is described. The method includes producing a two-dimensional array of spectrum values by imaging the optical spectrum onto a detector array. An offset using an actual location and an expected location of a peak of an interpolated subarray is used to adjust an expected location of another peak that is within another two-dimensional subarray. Interpolated spectrum values are then used to produce a peak intensity value of the second peak.Type: ApplicationFiled: July 30, 2020Publication date: August 11, 2022Inventors: Hans-Juergen Schlueter, Antonella Guzzonato, Norbert Quaas, Peter Huelstede
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AUTOMATED TEST MIX FOR GAS CHROMATOGRAPH/GAS CHROMATOGRAPHY-MASS SPECTROMETRY HEALTH AND DIAGNOSTICS
Publication number: 20220178890Abstract: Described are techniques for performing automated maintenance evaluations on a gas chromatograph (GC) or a gas chromatograph-mass spectrometer (GC-MS). Systems and methods are described for directing an injector of a GC or GC-MS instrument system to autonomously inject a diagnostic material sample into a material analysis chamber and initiate a scientific analysis to formulate a set of results. The systems and methods further include the instrument system analyzing the set of results generating one or more output reports.Type: ApplicationFiled: December 8, 2020Publication date: June 9, 2022Inventors: Deven L. SHINHOLT, Edward B. McCAULEY, Riccardo FACCHETTI, Antonella GUZZONATO -
Publication number: 20200378929Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.Type: ApplicationFiled: August 17, 2020Publication date: December 3, 2020Inventors: Antonella GUZZONATO, Heinz MEHLMANN, Hans-Juergen SCHLUETER
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Patent number: 10761069Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.Type: GrantFiled: July 29, 2019Date of Patent: September 1, 2020Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Antonella Guzzonato, Heinz Mehlmann, Hans-Juergen Schlueter
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Patent number: 10656130Abstract: An elemental analysis system includes a reactor having at least one reduction reaction zone including a metal zeolite that can reduce nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reduction. Correspondingly, a method of elemental analysis includes providing a reactor having at least one reduction reaction zone including a metal zeolite and reducing nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reaction on the metal zeolite.Type: GrantFiled: May 1, 2017Date of Patent: May 19, 2020Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Antonella Guzzonato, Christopher Brodie
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Publication number: 20190346410Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.Type: ApplicationFiled: July 29, 2019Publication date: November 14, 2019Inventors: Antonella GUZZONATO, Heinz MEHLMANN, Hans-Juergen SCHLUETER
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Patent number: 10365256Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.Type: GrantFiled: December 16, 2016Date of Patent: July 30, 2019Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Antonella Guzzonato, Heinz Mehlmann, Hans-Juergen Schlueter
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Publication number: 20170336374Abstract: An elemental analysis system includes a reactor having at least one reduction reaction zone including a metal zeolite that can reduce nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reduction. Correspondingly, a method of elemental analysis includes providing a reactor having at least one reduction reaction zone including a metal zeolite and reducing nitrogen oxides (NOx) to molecular nitrogen (N2) by selective catalytic reaction on the metal zeolite.Type: ApplicationFiled: May 1, 2017Publication date: November 23, 2017Inventors: Antonella GUZZONATO, Christoper BRODIE
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Publication number: 20170184552Abstract: A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.Type: ApplicationFiled: December 16, 2016Publication date: June 29, 2017Inventors: Antonella GUZZONATO, Heinz MEHLMANN, Hans-Juergen SCHLUETER