Patents by Inventor Antonella Torosantucci

Antonella Torosantucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protective anti-glucan antibodies with preference for ?-1,3-glucans
    Patent number: 8414889
    Abstract: Anti-?-1,3-glucan antibodies have been found to be protective against systemic fungal infection with Candida albicans. The present invention provides monoclonal antibodies that bind to ?-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly against Candida albicans and Aspergillus fumigatis infections. The antibodies of the present invention are not specific for ?-1,6-glucan.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: April 9, 2013
    Inventors: Antonio Cassone, Antonella Torosantucci
  • PROTECTIVE ANTI-GLUCAN ANTIBODIES WITH PREFERENCE FOR BETA-1,3-GLUCANS
    Publication number: 20120107316
    Abstract: Anti-?-1,3-glucan antibodies have been found to be protective against systemic fungal infection with Candida albicans. The present invention provides monoclonal antibodies that bind to ?-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly against Candida albicans and Aspergillus fumigatis infections. The antibodies of the present invention are not specific for ?-1,6-glucan.
    Type: Application
    Filed: December 20, 2011
    Publication date: May 3, 2012
    Inventors: Antonio CASSONE, Antonella Torosantucci
  • Protective anti-glucan antibodies with preference for ?-1,3-glucans
    Patent number: 8101406
    Abstract: Anti-?-1,3-glucan antibodies have been found to be protective against systemic fungal infection with Candida albicans. The present invention provides monoclonal antibodies that bind to ?-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly against Candida albicans and Aspergillus fumigatis infections. The antibodies of the present invention are not specific for (?-1,6-glucan.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: January 24, 2012
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Antonio Cassone, Antonella Torosantucci
  • Protective anti-glucan antibodies with preference for ?-1,3- glucans
    Patent number: 7893219
    Abstract: Anti-?-1,3-glucan antibodies have been found to be protective against systemic fungal infection with Candida albicans. The present invention provides monoclonal antibodies that bind to ?-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly against Candida albicans and Aspergillus fumigatis infections. The antibodies of the present invention are not specific for ?-1,6-glucan.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: February 22, 2011
    Assignee: Novartis Vaccines & Diagnostics, Inc.
    Inventors: Antonio Cassone, Antonella Torosantucci
  • PROTECTIVE ANTI-GLUCAN ANTIBODIES WITH PREFERENCE FOR BETA-1,3-GLUCANS
    Publication number: 20100297130
    Abstract: Anti-?-1,3-glucan antibodies have been found to be protective against systemic fungal infection with Candida albicans. The present invention provides monoclonal antibodies that bind to ?-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly against Candida albicans and Aspergillus fumigatis infections. The antibodies of the present invention are not specific for (?-1,6-glucan.
    Type: Application
    Filed: August 6, 2010
    Publication date: November 25, 2010
    Inventors: Antonio Cassone, Antonella Torosantucci
  • Protective anti-glucan antibodies with preference for beta-1,3- glucans
    Publication number: 20090214566
    Abstract: Anti-?-1,3-glucan antibodies have been found to be protective against systemic fungal infection with Candida albicans. The present invention provides monoclonal antibodies that bind to ?-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly against Candida albicans and Aspergillus fumigatis infections. The antibodies of the present invention are not specific for ?-1,6-glucan.
    Type: Application
    Filed: September 14, 2005
    Publication date: August 27, 2009
    Inventors: Antonio Cassone, Antonella Torosantucci