Patents by Inventor Antonette C. P. Allen

Antonette C. P. Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coding sequence haplotype of the human BRCA1 gene
    Patent number: 6686163
    Abstract: The invention is directed to isolated coding sequences and to the protein sequences they code for. The coding sequence for BRCA1(omi4) gene is provided together with the protein sequence it codes for. The BRCA1(omi4) sequence is used for identifying an individual having an increased genetic susceptibility to breast or ovarian cancer because the patient has an inherited causative mutation in their BRCA1 gene. This invention is also related to a method of performing gene therapy with the isolated BRCA1(omi4) coding sequence and protein replacement therapy with the BRCA1(omi4) protein.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: February 3, 2004
    Assignee: Gene Logic Inc.
    Inventors: Antonette C. P. Allen, Tracy S. Angelly, Tammy Lawrence, Sheri J. Olson, Mark B. Rabin
  • Coding sequences of the human BRCA1 gene
    Patent number: 6130322
    Abstract: This invention is directed to the isolated coding sequences and to the protein sequences they code for. This invention is directed to three coding sequence of the BRCA1 gene. The three coding sequences, BRCA1.sup.(omi1), BRCA1.sup.(omi2), and BRCA1.sup.(omi3) and their frequencies of occurrence are provided together with the protein sequences they code for. Another aspect of this invention is a method of determining the consensus sequence for any gene. Another aspect of the invention is a method of identifying an individual having an increased genetic susceptibility to breast or ovarian cancer because they have inherited a causative mutation in their BRCA1 gene. This invention is also related to a method of performing gene therapy with any of the isolated BRCA1 coding sequences. This invention is further related to protein therapy with BRCA.sup.(omi) proteins or their functional equivalent.
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: October 10, 2000
    Assignee: Gene Logic, Inc.
    Inventors: Patricia D. Murphy, Antonette C. P. Allen, Christopher P. Alvares, Brenda S. Critz, Sheri J. Olson, Denise Thurber, Bin Zeng