Patents by Inventor Antoni Niekraszewicz
Antoni Niekraszewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7482019Abstract: Disclosed are methods of producing modified microcrystalline chitosan. Chitosan in aqueous solution is degraded enzymatically, hydrolytically or oxidatively. The chitosan solution is then alkalized with agitation using aqueous hydroxides and/or their salts to attain a pH not lower than 7.0. The precipitated modified microcrystalline chitosan is highly pure and may be concentrated and dried according to known methods. Methods according to the invention also include methods by which an aqueous solution of chitosan is first alkalized using hydroxides and/or their salts to a pH not lower than 7.0. Then the precipitated microcrystalline chitosan is subjected to enzymatic or oxidative degradation to achieve a desired average molecular weight and polydispersity. The product is highly pure and may be concentrated and dried according to known methods.Type: GrantFiled: January 8, 2003Date of Patent: January 27, 2009Assignee: Abbott LaboratoriesInventors: Henryk Struszczyk, Antoni Niekraszewicz, Magdelena Kucharska, Alojzy Urbanowski, Maria Wisniewska-Wrona, Ewa Wesolowska, Danuta Ciechanska
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Publication number: 20070129326Abstract: Disclosed are methods of producing modified microcrystalline chitosan. Chitosan in aqueous solution is degraded enzymatically, hydrolytically or oxidatively. The chitosan solution is then alkalized with agitation using aqueous hydroxides and/or their salts to attain a pH not lower than 7.0. The precipitated modified microcrystalline chitosan is highly pure and may be concentrated and dried according to known methods. Methods according to the invention also include methods by which an aqueous solution of chitosan is first alkalized using hydroxides and/or their salts to a pH not lower than 7.0. Then the precipitated microcrystalline chitosan is subjected to enzymatic or oxidative degradation to achieve a desired average molecular weight and polydispersity. The product is highly pure and may be concentrated and dried according to known methods.Type: ApplicationFiled: November 27, 2006Publication date: June 7, 2007Applicant: ABBOTT LABORATORIESInventors: Henry Struszczyk, Antoni Niekraszewicz, Magdelena Kucharska, Alojzy Urbanowski, Maria Wisniewska-Wrona, Ewa Wesolowska, Danuta Ciechanska
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Publication number: 20070087997Abstract: Disclosed are methods of producing modified microcrystalline chitosan. Chitosan in aqueous solution is degraded enzymatically, hydrolytically or oxidatively. The chitosan solution is then alkalized with agitation using aqueous hydroxides and/or their salts to attain a pH not lower than 7.0. The precipitated modified microcrystalline chitosan is highly pure and may be concentrated and dried according to known methods. Methods according to the invention also include methods by which an aqueous solution of chitosan is first alkalized using hydroxides and/or their salts to a pH not lower than 7.0. Then the precipitated microcrystalline chitosan is subjected to enzymatic or oxidative degradation to achieve a desired average molecular weight and polydispersity. The product is highly pure and may be concentrated and dried according to known methods.Type: ApplicationFiled: November 27, 2006Publication date: April 19, 2007Applicant: ABBOTT LABORATORIESInventors: Henry Struszczyk, Antoni Niekraszewicz, Magdelena Kucharska, Alojzy Urbanowski, Maria Wisniewska-Wrona, Ewa Wesolowska, Danuta Ciechanska
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Publication number: 20070087415Abstract: Disclosed are methods of producing modified microcrystalline chitosan. Chitosan in aqueous solution is degraded enzymatically, hydrolytically or oxidatively. The chitosan solution is then alkalized with agitation using aqueous hydroxides and/or their salts to attain a pH not lower than 7.0. The precipitated modified microcrystalline chitosan is highly pure and may be concentrated and dried according to known methods. Methods according to the invention also include methods by which an aqueous solution of chitosan is first alkalized using hydroxides and/or their salts to a pH not lower than 7.0. Then the precipitated microcrystalline chitosan is subjected to enzymatic or oxidative degradation to achieve a desired average molecular weight and polydispersity. The product is highly pure and may be concentrated and dried according to known methods.Type: ApplicationFiled: November 27, 2006Publication date: April 19, 2007Applicant: ABBOTT LABORATORIESInventors: Henryk Struszczyk, Antoni Niekraszewicz, Magdelena Kucharska, Alojzy Urbanowski, Maria Wisniewska-Wrona, Ewa Wesolowska, Danuta Ciechanska
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Publication number: 20050159593Abstract: Methods for deproteinizing chitosan are provided. Proteins are dissolved in aqueous solution under intensive agitation. Precipitated agglomerated microcrystalline product Is subject to aqueous acidic or basic salt solution, from which dissolved proteins can be removed. Residual product is deproteinized chitosan.Type: ApplicationFiled: January 9, 2003Publication date: July 21, 2005Inventors: Henryk Struszczyk, Magdalena Kucharska, Antoni Niekraszewicz, Alojzy Urbanowski, Ewa Wesolowska, Danuta Ciechanska
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Publication number: 20050053663Abstract: Chitosan-calcium complexes of calcium (II) ions with a gel of a chitosan salt, containing not less than 0.5 wt % of the polymer with an average molecular weight not less than 10 kD, a polydispersity degree not lower than 2.0 and a deacetylation degree at least 65%. The complex is characterized by pH not higher than 6.9 and a calcium Ca (II) ions content not less than 0.1 wt % on chitosan. Methods to prepare chitosan-calcium complexes use a gel of a chitosan salt, containing not less than 0.5 wt % of the polymer. Calcium salts are introduced in the amount of at least 0.1 wt % Ca (II) on chitosan weight. The mixture is next homogenized and reacted at 10° C. during a time not shorter than 1 minute. Methods of producing a gel of chitosan salts involves subjecting a chitosan with the concentration of at least 0.5 wt % in an aqueous acidic solution to a controlled enzymatic, hydrolytic or oxidative degradation.Type: ApplicationFiled: January 8, 2003Publication date: March 10, 2005Inventors: Henryk Struszczyk, Antoni Niekraszewicz, Magdelena Kucharska, Alojzy Urbanowski, Kinga Brzoza, Danuta Ciechanska, Maria Wisniewska-Wrona
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Publication number: 20050019873Abstract: Disclosed are methods of producing modified microcrystalline chitosan. Chitosan in aqueous solution is degraded enzymatically, hydrolytically or oxidatively. The chitosan solution is then alkalized with agitation using aqueous hydroxides and/or their salts to attain a pH not lower than 7.0. The precipitated modified microcrystalline chitosan is highly pure and may be concentrated and dried according to known methods. Methods according to the invention also include methods by which an aqueous solution of chitosan is first alkalized using hydroxides and/or their salts to a pH not lower than 7.0. Then the precipitated microcrystalline chitosan is subjected to enzymatic or oxidative degradation to achieve a desired average molecular weight and polydispersity. The product is highly pure and may be concentrated and dried according to known methods.Type: ApplicationFiled: January 8, 2003Publication date: January 27, 2005Inventors: Henryk Struszczyk, Antoni Niekraszewicz, Magdelena Kucharska, Alojzy Urbanowski, Maria Wisniewska-Wrona, Ewa Wesolowska, Danuta Ciechanska
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Patent number: 6740752Abstract: Disclosed is a process for producing particles of the modified carbohydrate polymer chitosan. Such chitosan particles are “activated” as a consequence of the specific steps used in the process. The process involves precipitation of dissolved chitosan from an acid solution thereof by the step-wise addition of neutralizing agent to the solution. A partial neutralization is carried out under shear agitation to form a continuous gel phase having a pH within the range of 5.0 to 6.9. This partially neutralized chitosan gel phase is then further subjected to shear agitation for at least 10 seconds to homogenize the gel phase. The homogenized gel phase is then further neutralized under shear agitation to a pH of above 6.9 to form a gel-like suspension of discrete chitosan particles. Chitosan particles in this form are useful in a number of contexts including, in particular, in the area of plant care.Type: GrantFiled: October 23, 2002Date of Patent: May 25, 2004Assignee: The Procter & Gamble CompanyInventors: Henryk Struszcyk, Antoni Niekraszewicz, Magdalena Kucharska, Alojzy Urbanowski, Maria Wisniewska-Wrona
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Publication number: 20030119672Abstract: Disclosed are bioagent compositions for plant care which can be used for treatment of plants and seeds. Such treatment serves to inhibit the activity of plant pathogens against the treated plants, stimulate natural plant immunity against such pathogens and provides plant growth biostimulation. The compositions comprise a chitosan polymer which can either be in the form of particles of microcrystalline chitosan which are in a composition of pH greater than 6.9, or in the form of a chitosan salt gel which are in a composition of pH of from 5.0 to 6.9. In either form, the chitosan polymer has specified molecular weight, polydispersity degree and degree of deacetylation characteristics. Preferably the chitosan polymer has a bimodal molecular weight distribution and contains a fraction of water-soluble oligoaminocarbohydrates.Type: ApplicationFiled: November 12, 2002Publication date: June 26, 2003Applicant: The Procter & Gamble CompanyInventors: Henryk Struszczyk, Antoni Niekraszewicz, Henryk Pospieszny, Alojzy Urbanowski, Maria Wisniewska-Wrona, Magdalena Kucharska
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Publication number: 20030057159Abstract: Disclosed is a process for producing particles of the modified carbohydrate polymer chitosan. Such chitosan particles are “activated” as a consequence of the specific steps used in the process. The process involves precipitation of dissolved chitosan from an acid solution thereof by the step-wise addition of neutralizing agent to the solution. A partial neutralization is carried out under shear agitation to form a continuous gel phase having a pH within the range of 5.0 to 6.9. This partially neutralized chitosan gel phase is then further subjected to shear agitation for at least 10 seconds to homogenize the gel phase. The homogenized gel phase is then further neutralized under shear agitation to a pH of above 6.9 to form a gel-like suspension of discrete chitosan particles. Chitosan particles in this form are useful in a number of contexts including, in particular, in the area of plant care.Type: ApplicationFiled: October 23, 2002Publication date: March 27, 2003Applicant: The Procter & Gamble CompanyInventors: Henryk Struszczyk, Antoni Niekraszewicz, Magdalena Kucharska, Alojzy Urbanowski, Maria Wisniewska-Wrona
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Patent number: 5622666Abstract: Modified viscose fibres comprise regenerated cellulose and contain in their structure microcrystalline chitosan bound mainly by hydrogen bonds with the regenerated cellulose of viscose fibres. To improve the properties of the fibres the modified fibres contain as a third component a water-soluble and/or alkali-soluble natural polymer or a derivative thereof of polysaccharide origin containing groups bound by hydrogen and/or ionic bonds with the microcrystalline chitosan. Examples of such polymers are alginic acid, sodium and potassium alginate and sodium carboxymethycellulose.Type: GrantFiled: June 7, 1995Date of Patent: April 22, 1997Assignee: Novasso OyInventors: Henryk Struszczyk, Pertti Nousiainen, Olli Kivekas, Antoni Niekraszewicz
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Patent number: 5543494Abstract: Poly(lactic acid) with a high molecular weight is produced by the polycondensation reaction of the free monomer carried out in the presence of a catalytically effective quantity of iron ions. High molecular weight poly(lactic acid) and lactide are obtained as the principal products.Type: GrantFiled: January 27, 1995Date of Patent: August 6, 1996Assignee: Ministero Dell'Univerita' E Della Ricerca Scientifica E TecnologicaInventors: Gabriele Perego, Catia Bastioli, Karolina Grzebieniak, Antoni Niekraszewicz