Patents by Inventor Antonin Fougerolles

Antonin Fougerolles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNAI INHIBITION OF INFLUENZA VIRUS REPLICATION
    Publication number: 20070197460
    Abstract: The invention relates to compositions and methods for modulating the expression of influenza viral genes, and more particularly to the downregulation of influenza viral genes by chemically modified oligonucleotides.
    Type: Application
    Filed: November 1, 2006
    Publication date: August 23, 2007
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: Antonin Fougerolles, Tatiana Novobrantseva, Pamela Tan, Anke Geick, Rachel Meyers
  • RNAi modulation of HIF-1 and therapeutic uses thereof
    Publication number: 20070155686
    Abstract: The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of HIF-1?, such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
    Type: Application
    Filed: June 27, 2006
    Publication date: July 5, 2007
    Inventors: Akin Akinc, Antonin Fougerolles, Hans-Peter Vornlocher, Philipp Hadwiger
  • IRNA agents targeting VEGF
    Publication number: 20060223770
    Abstract: The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of vascular endothelial growth factor (VEGF), such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
    Type: Application
    Filed: January 25, 2006
    Publication date: October 5, 2006
    Inventors: Antonin Fougerolles, Maria Frank-Kamenetsky, Muthiah Manoharan, Kallanthottathil Rajeev, Philipp Hadwiger
  • Compositions and methods for inducing an immune response in a mammal and methods of avoiding an immune response to oligonucleotide agents such as short interfering RNAs
    Publication number: 20060217330
    Abstract: This invention provides oligonucleotide agents that modulate an immune response by stimulating IFN production and methods of using such agents for therapeutic treatments of mammals.
    Type: Application
    Filed: December 9, 2005
    Publication date: September 28, 2006
    Inventors: Gunther Hartmann, Antonin Fougerolles, Veit Hornung, Stefan Endres
  • iRNA agents targeting VEGF
    Publication number: 20060094032
    Abstract: The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of vascular endothelial growth factor (VEGF), such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
    Type: Application
    Filed: March 11, 2005
    Publication date: May 4, 2006
    Inventors: Antonin Fougerolles, Maria Frank-Kamenetsky, Muthiah Manoharan, Kallanthottathil Rajeev, Philipp Hadwiger